• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

1227675-50-4 (A 943931 dihydrochloride)

1

Identification

A 943931 dihydrochloride A 943931 dihydrochloride
Name A 943931 dihydrochloride
Formula C17H23Cl2N5
MW 368.3
CAS No. 1227675-50-4
EINECS
Smiles N[[email protected]@]1(CCN(C1)C(C2=C(C3=CC=CC=C3CCC2)N4)=NC4=N)[H].Cl.Cl
Synonyms (R)-1-(2-imino-2,5,6,7-tetrahydro-1H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-4-yl)pyrrolidin-3-amine dihydrochloride
InChI InChI=1S/C17H21N5.2ClH/c18-12-8-9-22(10-12)16-14-7-3-5-11-4-1-2-6-13(11)15(14)20-17(19)21-16;;/h1-2,4,6,12H,3,5,7-10,18H2,(H2,19,20,21);2*1H/t12-;;/m1../s1
2

Introduction

Background Information

Potent and selective histamine H4 receptor antagonist (pKi values are 7.15 and 8.12 at human and rat receptors respectively). Blocks inflammation in a peritonitis mouse model and displays efficacy in inflammatory pain and neuropathic pain models. ......by Tocris Bioscience Inc.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance: EBNumber:EB000123737

Storage condition

Store at +4°C by Tocris Bioscience Inc.

Solubility

Soluble to 100 mM in water and to 100 mM in DMSO by Tocris Bioscience Inc.
5

Mechanism and Indication

Signaling Pathways
Target
Research Area
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
7

Safety Data of A 943931 dihydrochloride

8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Tocris Bioscience Inc. USA
10

Related Products

Other Forms of 1227675-50-4

Name CAS No Formula MW

Recommended Compounds in

Name CAS No Formula MW

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

Protocol Reference

13

More Information

A 943931 dihydrochloride

Tags: buy 1227675-50-4 IC50 | 1227675-50-4 price | 1227675-50-4 cost | 1227675-50-4 solubility | 1227675-50-4 purchase | 1227675-50-4 manufacturer | 1227675-50-4 research buy | 1227675-50-4 order | 1227675-50-4 MSDS | 1227675-50-4 chemical structure | 1227675-50-4 Storage condition | 1227675-50-4 molecular weight | 1227675-50-4 mw | 1227675-50-4 datasheet | 1227675-50-4 supplier | 1227675-50-4 cell line | 1227675-50-4 NMR | 1227675-50-4 MS | 1227675-50-4 IR | 1227675-50-4 solubility | 1227675-50-4 Safe information | 1227675-50-4 Qc and Spectral Information | 1227675-50-4 Clinical Information | 1227675-50-4 Clinical Trial | 1227675-50-4 Route of Synthesis | 1227675-50-4 storage condition | 1227675-50-4 diseases and conditions | 1227675-50-4 flash point | 1227675-50-4 boiling point | 1227675-50-4 melting point | 1227675-50-4 storage condition | 1227675-50-4 brand