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145307-34-2 (A 77636 hydrochloride)

1

Identification

A 77636 hydrochloride A 77636 hydrochloride
Name A 77636 hydrochloride
Formula C20H28ClNO3
MW 365.89
CAS No. 145307-34-2
EINECS
Smiles OC1=C(O)C=CC2=C1C[[email protected]@H]([[email protected]]34C[[email protected]@H](C[[email protected]](C4)C5)C[[email protected]@H]5C3)O[[email protected]]2CN.Cl
Synonyms (1R,3S)-3-((1s,3R,5R,7S)-adamantan-1-yl)-1-(aminomethyl)isochroman-5,6-diol hydrochloride
InChI InChI=1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11-,12-,13-,17-,18-,20-;/m0./s1
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Introduction

Background Information

Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. ......by Tocris Bioscience Inc.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000123595

Storage condition

Store at -20°C by Tocris Bioscience Inc.

Solubility

Soluble to 100 mM in water by Tocris Bioscience Inc.
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Mechanism and Indication

Signaling Pathways
Target
Research Area
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
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Safety Data of A 77636 hydrochloride

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
Shanghai Haoyuan Chemexpress Co., Ltd. China
Tocris Bioscience Inc. USA
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Related Products

Other Forms of 145307-34-2

Name CAS No Formula MW

Recommended Compounds in

Name CAS No Formula MW

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

Protocol Reference

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More Information

A 77636 hydrochloride

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