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80418-25-3 (Notoginsenoside R2)

1

Identification

Notoginsenoside R2 Notoginsenoside R2
Name Notoginsenoside R2
Formula C41H70O13
MW 770.99
CAS No. 80418-25-3
EINECS
Smiles C[[email protected]]([[email protected]@](C[[email protected]]1O)([H])[[email protected]]2(CC[[email protected]@H]3O)C)(C[[email protected]](O[[email protected]@](O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]4O)([H])[[email protected]@H]4O[[email protected]@](OC[[email protected]@H](O)[[email protected]@H]5O)([H])[[email protected]@H]5O)[[email protected]@]2([H])C3(C)C)[[email protected]]6([[email protected]@]1([H])[[email protected]]([[email protected]@](C)(O)CC/C=C(C)/C)([H])CC6)C
Synonyms 20(S)-Notoginsenoside R2;Ginsenoside Ng-R2; (2S,3R,4S,5R)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol
InChI InChI=1S/C41H70O13/c1-20(2)10-9-13-41(8,50)21-11-15-39(6)28(21)22(43)16-26-38(5)14-12-27(45)37(3,4)34(38)24(17-40(26,39)7)52-36-33(31(48)30(47)25(18-42)53-36)54-35-32(49)29(46)23(44)19-51-35/h10,21-36,42-50H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26+,27-,28-,29-,30+,31-,32+,33+,34-,35-,36+,38+,39+,40+,41-/m0/s1
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Introduction

Notoginsenoside R2 is a newly isolated notoginsenoside from Panax notoginseng, showed neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.

Background Information

The neuroprotection elicited by Notoginsenoside R2 against 6-OHDA-induced neurotoxicity was associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways. ......by BOC Sciences
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000070820

Storage condition

Solubility

10 mM in DMSO by CHEMSCENE, LLC
10 mM in DMSO by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Others
Target Others
Research Area Neurological Disease
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Notoginsenoside R2 - Not Found
Notoginsenoside R2 - No Development Reported
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Safety Data of Notoginsenoside R2

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
BOC Sciences
CHEMSCENE, LLC 5mg/USD144();10mg/USD240() USA
MedChemexpress Co., Ltd. 5mg/USD144();10mg/USD240() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5mg/USD144();10mg/USD240() China
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Related Products

Other Forms of 80418-25-3

Name CAS No Formula MW

Recommended Compounds in Others

Name CAS No Formula MW
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 320.74
Dictamine 484-29-7 C12H9NO2 199.21
3,3',5-Triiodo-L-thyronine (sodium) 55-06-1 C15H11I3NNaO4 672.9553
Fabomotizole (hydrochloride) 173352-39-1 C15H22ClN3O2S 343.8721
FPH2 957485-64-2 C14H16ClN5O2S 353.83
╬▒-Tocopherol (phosphate) 38976-17-9 C29H51O5P 510.69
BAMB-4 891025-25-5 C15H12N2O2 252.27
LDN-27219 312946-37-5 C20H16N4O2S2 408.5
ISO-1 478336-92-4 C12H13NO4 235.24
Aurothioglucose 12192-57-3 C6H11AuO5S 392.18
Oxybenzone 131-57-7 C14H12O3 228.24
ITX3 347323-96-0 C22H17N3OS 371.45
Cardiogreen 3599-32-4 C43H47N2NaO6S2 774.96
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 465.34
INH1 313553-47-8 C18H16N2OS 308.4
PF6-AM 1268491-69-5 C33H31BO12 630.4
XEN445 1515856-92-4 C18H17F3N2O3 366.33
Disperse Blue 148 52239-04-0 C19H19N5O4S 413.45026
Solvent Blue 35 17354-14-2 C22H26N2O2 350.454
CID-797718 370586-05-3 C12H11NO3 217.2206

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Notoginsenoside R2

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