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808-26-4 (Sancycline)

1

Identification

Sancycline Sancycline
Name Sancycline
Formula C21H22N2O7
MW 414.41
CAS No. 808-26-4
EINECS
Smiles O[[email protected]]1(C(O)=C2C3=O)[[email protected]](C[[email protected]]2([H])CC4=C3C(O)=CC=C4)([H])[[email protected]](N(C)C)C(O)=C(C(N)=O)C1=O
Synonyms (4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
InChI InChI=1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24,26-27,30H,6-7H2,1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1
2

Introduction

Background Information

Sancycline is a tetracycline bacteriostatic antibiotic which can bind to the Tet repressor protein (TetR). It is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin. It acts by reversibly ......by BOC Sciences
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000013204

Storage condition

Solubility

DMSO: > 10 mg/mL by CHEMSCENE, LLC
DMSO: > 10 mg/mL by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways Anti-infection
Target Bacterial
Research Area Infection
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Sancycline - Launched
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Safety Data of Sancycline

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Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Archimica Inc. USA
BOC Sciences 25mg/USD178(In stock)
Biochempartner Co., Ltd 5mg/USD144();10mg/USD214() China
CHEMSCENE, LLC 1mg/USD72();5mg/USD114() USA
MedChemexpress Co., Ltd. 1mg/USD72();5mg/USD114() USA
Santa Cruz Biotechnology, Inc. 1mg/USD125() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 1mg/USD72();5mg/USD114() China
Sigma-Aldrich, Inc. 1mg/USD125() USA
Toronto Research Chemicals Inc. 1mg/USD95(2-3 weeks);5mg/USD150();50mg/USD1200() Canada
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Related Products

Other Forms of 808-26-4

Name CAS No Formula MW

Recommended Compounds in Bacterial

Name CAS No Formula MW
Fidaxomicin 873857-62-6 C52H74Cl2O18 1058.04
AVX 13616 900814-48-4 C50H73Cl2N7O7 955.06
Bedaquiline (fumarate) 845533-86-0 C36H35BrN2O6 671.58
Mafenide (Acetate) 13009-99-9 C9H14N2O4S 246.28
Cefozopran 113359-04-9 C19H17N9O5S2 515.53
Azithromycin 83905-01-5 C38H72N2O12 748.9845
Pazufloxacin 127045-41-4 C16H15FN2O4 318.3
Pazufloxacin (mesylate) 163680-77-1 C17H19FN2O7S 414.4054
Capreomycin (sulfate) 1405-37-4 C24H44N14O12S 752.76
Bleomycin (sulfate) 9041-93-4 C110H168N34O46S7 2927.17
G-418 (disulfate) 108321-42-2 C20H44N4O18S2 692.71
Demeclocycline (hydrochloride) 64-73-3 C21H22Cl2N2O8 501.31
Apramycin 37321-09-8 C21H41N5O11 539.58
Ceftriaxone 73384-59-5 C18H18N8O7S3 554.58
Ceftibuten 97519-39-6 C15H14N4O6S2 410.42
Dapsone 80-08-0 C12H12N2O2S 248.3
Vancomycin 1404-90-6 C66H76Cl3N9O24 1485.72
Lomefloxacin 98079-51-7 C17H19F2N3O3 351.35
Dirithromycin 62013-04-1 C42H78N2O14 835.07
Cefepime (Dihydrochloride Monohydrate) 123171-59-5 C19H28Cl2N6O6S2 571.5

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

12

References

Protocol Reference

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More Information

Sancycline

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