• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

60-80-0 (Antipyrine)

1

Identification

Antipyrine Antipyrine
Name Antipyrine
Formula C11H12N2O
MW 188.23
CAS No. 60-80-0
EINECS 200-486-6
Smiles CN(C(C)=C1)N(C1=O)C2=CC=CC=C2
Synonyms 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone; 1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
InChI InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3
2

Introduction

Antipyrine is an analgesic and antipyretic agent. Target: Others Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops.

Background Information

Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic. ......by BOC Sciences
Antipyrine is an analgesic and antipyretic agent. Target: Others Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine was one of the first important synthetic drugs. antipyrine went into widespread clinical use as an antipyretic the same year it was synthesized. Two years after its introduction, reports began to appear of its analgesic effects and in the succeeding years, as the use of antipyrine as an antipyretic declined, it gained considerable popularity as an analgesic. The plasma halflife of antipyrine is significantly longer and the clearance significantly lower in the elderly group. This finding of an impaired metabolism of antipyrine in the elderly has since been confirmed in a much larger study and subsequently other drugs have been shown to be metabolized more slowly in this age group [1]. ......by MedChemexpress Co., Ltd.
Antipyrine is an analgesic and antipyretic agent. ......by Selleck Chemicals LLC
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. . ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012918

Storage condition

Solubility

DMSO 40 mg/mL; Water 40 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 38 mg/mL (201.88 mM); Water38 mg/mL (201.88 mM); Ethanol38 mg/mL (201.88 mM) by Selleck Chemicals LLC
5

Mechanism and Indication

Signaling Pathways Others
Target Others
Research Area Inflammation/Immunology
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Antipyrine - Launched
7

Safety Data of Antipyrine

Hazard Symbols : Xn
Risk Statements : R22;R36/37/38
Safety Statements : S26;S37/39
RTECS : CD2450000
WGKGermany : 1
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Anhui Jin�ao Chemical Co., Ltd. China
BOC Sciences
CHEMSCENE, LLC USA
Hubei Widely Chemical Technology Co., Ltd. China
MedChemexpress Co., Ltd. 50mg/USD55(In stock);100mg/USD80(In stock) USA
Pure Chemistry Scientific Inc. 1kg/USD260(In stock) USA
Selleck Chemicals LLC 50mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 25g/USD7(Get quote);100g/USD22(Get quote) China
Target Molecule Corp. 2mg/USD20();10mg/USD83();50mg/USD174();200mg/USD259() USA
Xi'an Huayao Pharm-Chem Institute China
10

Related Products

Other Forms of 60-80-0

Name CAS No Formula MW

Recommended Compounds in Others

Name CAS No Formula MW
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 320.74
Dictamine 484-29-7 C12H9NO2 199.21
Liothyronine (sodium) 55-06-1 C15H11I3NNaO4 672.96
Afobazole (hydrochloride) 173352-39-1 C15H22ClN3O2S 343.87
FPH2 957485-64-2 C14H16ClN5O2S 353.83
α-Tocopherol (phosphate) 38976-17-9 C29H51O5P 510.69
BAMB-4 891025-25-5 C15H12N2O2 252.27
LDN-27219 312946-37-5 C20H16N4O2S2 408.5
ISO-1 478336-92-4 C12H13NO4 235.24
Aurothioglucose 12192-57-3 C6H11AuO5S 392.18
Oxybenzone 131-57-7 C14H12O3 228.24
ITX3 347323-96-0 C22H17N3OS 371.45
Cardiogreen 3599-32-4 C43H47N2NaO6S2 774.96
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 465.34
INH1 313553-47-8 C18H16N2OS 308.4
PF6-AM 1268491-69-5 C33H31BO12 630.4
XEN445 1515856-92-4 C18H17F3N2O3 366.33
Methyl N-ethyl-N-4-(5-nitro-2,1-benzisothiazol-3-yl)azophenyl-alaninate 52239-04-0 C19H19N5O4S 413.45
1,4-bis(Butylamino)anthraquinone 17354-14-2 C22H26N2O2 350.45
CID 797718 370586-05-3 C12H11NO3 217.22

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Antipyrine

Tags: buy 60-80-0 IC50 | 60-80-0 price | 60-80-0 cost | 60-80-0 solubility | 60-80-0 purchase | 60-80-0 manufacturer | 60-80-0 research buy | 60-80-0 order | 60-80-0 MSDS | 60-80-0 chemical structure | 60-80-0 Storage condition | 60-80-0 molecular weight | 60-80-0 mw | 60-80-0 datasheet | 60-80-0 supplier | 60-80-0 cell line | 60-80-0 NMR | 60-80-0 MS | 60-80-0 IR | 60-80-0 solubility | 60-80-0 Safe information | 60-80-0 Qc and Spectral Information | 60-80-0 Clinical Information | 60-80-0 Clinical Trial | 60-80-0 Route of Synthesis | 60-80-0 storage condition | 60-80-0 diseases and conditions | 60-80-0 flash point | 60-80-0 boiling point | 60-80-0 melting point | 60-80-0 storage condition | 60-80-0 brand