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60-31-1 (Acetylcholine chloride)



Acetylcholine chloride Acetylcholine chloride
Name Acetylcholine chloride
Formula C7H16ClNO2
MW 181.66
CAS No. 60-31-1
EINECS 200-468-8
Smiles C[N+](C)(C)CCOC(C)=O.[Cl-]
Synonyms 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride; 2-acetoxy-N,N,N-trimethylethanaminium chloride
InChI InChI=1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1


Acetylcholine is a neurotransmitter that can induce the opening of calcium channels.

Background Information

Acetylcholine is an organic molecule that acts as a neurotransmitter in many organisms, including humans. ......by BOC Sciences
Acetylcholine is a neurotransmitter that can induce the opening of calcium channels. Target: Calcium Channel; nAChR; mAChR Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications. Acetylcholine chloride, more commonly referred to as just acetylcholine, is a cholinergic neurotransmitter that can induce the opening of calcium channels, as well as act on nicotinic and muscarinic acetylcholine receptors. Acetylcholine plays an important role at many sites in the central nervous system. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Studies show that non-neuronal acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions [1-3]. ......by MedChemexpress Co., Ltd.
The chemical compound Acetylcholine Chloride is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans. ......by Selleck Chemicals LLC
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. ......by Target Molecule Corp.
Endogenous neurotransmitter. Acts at nicotinic and muscarinic acetylcholine receptors. ......by Tocris Bioscience Inc.

Protocol(Only for Reference)

Cell Experiment

Animal Experiment


Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012595

Storage condition

Desiccate at RT by Tocris Bioscience Inc.


DMSO 35 mg/mL; Water 35 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 36 mg/mL (198.17 mM); Water36 mg/mL (198.17 mM); Ethanol36 mg/mL (198.17 mM) by Selleck Chemicals LLC
Soluble to 100 mM in water and to 100 mM in DMSO by Tocris Bioscience Inc.

Mechanism and Indication

Signaling Pathways Membrane Transporter/Ion Channel Autophagy
Target Calcium Channel Autophagy
Research Area Neurological Disease

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Acetylcholine chloride - Launched

Safety Data of Acetylcholine chloride

Hazard Symbols : Xi
Risk Statements : R36/37/38
Safety Statements : S26;S37/39
HS Code : 29379000
RTECS : FZ9800000
WGKGermany : 2

Spectral Information


Suppliers List

Company Price and Availability Country/Region
BOC Sciences
Discovery Fine Chemicals Ltd.
Frapp's Chemical (NFTZ) Co., Ltd. China
MedChemexpress Co., Ltd. 1g/USD60(In stock);5g/USD90(In stock) USA
Selleck Chemicals LLC 50mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 1g/USD23(Get quote);25g/USD35(Get quote);100g/USD116(Get quote) China
Taizhou Ingore Bio & Tech Co., Ltd. China
Target Molecule Corp. 2mg/USD20();10mg/USD42();50mg/USD98();200mg/USD122() USA
Tocris Bioscience Inc. USA

Related Products

Other Forms of 60-31-1

Name CAS No Formula MW
Acetylcholine iodide 2260-50-6 C7H16INO2 273.11

Recommended Compounds in Calcium Channel Autophagy

Name CAS No Formula MW
Lercanidipine (hydrochloride) 132866-11-6 C36H42ClN3O6 648.19
Amlodipine maleate 88150-47-4 C24H29ClN2O9 524.95
Lercanidipine 100427-26-7 C36H41N3O6 611.73
Neomycin (sulfate) 1405-10-3 C23H48N6O17S 712.72
Tetracaine (hydrochloride) 136-47-0 C15H25ClN2O2 300.82
Nitrendipine 39562-70-4 C18H20N2O6 360.36
Manidipine 89226-50-6 C35H38N4O6 610.7
Chlorpromazine (hydrochloride) 69-09-0 C17H20Cl2N2S 355.33
Ibutilide (fumarate) 122647-32-9 C44H76N4O10S2 885.23
Flunarizine (dihydrochloride) 30484-77-6 C26H28Cl2F2N2 477.42
Lacidipine 103890-78-4 C26H33NO6 455.54
Cromolyn (sodium) 15826-37-6 C23H14Na2O11 512.33
Amlodipine 88150-42-9 C20H25ClN2O5 408.88
Felodipine 72509-76-3 C18H19Cl2NO4 384.25
Nifedipine 21829-25-4 C17H18N2O6 346.33
Ranolazine 95635-55-5 C24H33N3O4 427.54
Nimodipine 66085-59-4 C21H26N2O7 418.44
Isradipine 75695-93-1 C19H21N3O5 371.39
Zonisamide (sodium) 68291-98-5 C8H7N2NaO3S 234.21
Zonisamide 68291-97-4 C8H8N2O3S 212.23

Recommended Compounds in Same Indication

Name CAS No Formula MW

Route of Synthesis




More Information

Acetylcholine chloride

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