• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

141136-83-6 (TRAP-6)

1

Identification

TRAP-6 TRAP-6
Name TRAP-6
Formula C34H56N10O9
MW 748.87
CAS No. 141136-83-6
EINECS
Smiles O=C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CCCNC(N)=N)C(N[[email protected]](C(O)=O)CC(N)=O)=O)=O)=O)[[email protected]@H](NC([[email protected]@H](N)CO)=O)CC1=CC=CC=C1
Synonyms Ser-Phe-Leu-Leu-Arg-Asn;Thrombin Receptor Activator Peptide 6; (2S,5S,8S,11S,14S,17S)-17-amino-2-(2-amino-2-oxoethyl)-14-benzyl-5-(3-guanidinopropyl)-18-hydroxy-8,11-diisobutyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecan-1-oic acid
InChI InChI=1S/C34H56N10O9/c1-18(2)13-23(30(49)40-22(11-8-12-39-34(37)38)29(48)44-26(33(52)53)16-27(36)46)42-31(50)24(14-19(3)4)43-32(51)25(41-28(47)21(35)17-45)15-20-9-6-5-7-10-20/h5-7,9-10,18-19,21-26,45H,8,11-17,35H2,1-4H3,(H2,36,46)(H,40,49)(H,41,47)(H,42,50)(H,43,51)(H,44,48)(H,52,53)(H4,37,38,39)/t21-,22-,23-,24-,25-,26-/m0/s1
2

Introduction

TRAP-6 is protease-activated receptor 1 (PAR1) agonist. Target: PAR1 in vitro: TRAP-6 stimulates transient mobilization of free intracellular calcium, platelet aggregation (EC50 = 0.8μM) and rapidly phosphorylates PDE3A.

Background Information

TRAP-6, a peptide compound, has been found to be a PAR1 agonist and could also influence the phosphorylation of rapid phosphodiesterase 3A in the positive way. ......by BOC Sciences
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000066609

Storage condition

Solubility

DMSO: > 28 mg/mL by CHEMSCENE, LLC
DMSO: > 28 mg/mL by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways GPCR/G Protein
Target Protease-Activated Receptor (PAR)
Research Area Inflammation/Immunology
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
TRAP-6 - Not Found
TRAP-6 - No Development Reported
7

Safety Data of TRAP-6

WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
BOC Sciences
CHEMSCENE, LLC 5mg/USD144();10mg/USD240() USA
MedChemexpress Co., Ltd. 5mg/USD144();10mg/USD240() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5mg/USD144();10mg/USD240() China
10

Related Products

Other Forms of 141136-83-6

Name CAS No Formula MW

Recommended Compounds in Protease-Activated Receptor (PAR)

Name CAS No Formula MW
AC-55541 916170-19-9 C25H20BrN5O3 518.362
Vorapaxar 618385-01-6 C29H33FN2O4 492.58
TFLLR-NH2 197794-83-5 C31H53N9O6 647.81
Protease-Activated Receptor-2, amide C28H54N8O7 614.8
Protease-Activated Receptor-4 C33H46N8O7 666.77
AZ3451 C30H27BrN4O3 571.46
AZ8838 C13H15FN2O 234.27
SB89 C20H20FNO3 341.38
SB70 C20H20FNO3 341.38
AZ6343 C11H14N2O 190.24
AZ7188 C17H14N2O 262.31
GB110 C33H48N6O5 608.77

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

TRAP-6

Tags: buy 141136-83-6 IC50 | 141136-83-6 price | 141136-83-6 cost | 141136-83-6 solubility | 141136-83-6 purchase | 141136-83-6 manufacturer | 141136-83-6 research buy | 141136-83-6 order | 141136-83-6 MSDS | 141136-83-6 chemical structure | 141136-83-6 Storage condition | 141136-83-6 molecular weight | 141136-83-6 mw | 141136-83-6 datasheet | 141136-83-6 supplier | 141136-83-6 cell line | 141136-83-6 NMR | 141136-83-6 MS | 141136-83-6 IR | 141136-83-6 solubility | 141136-83-6 Safe information | 141136-83-6 Qc and Spectral Information | 141136-83-6 Clinical Information | 141136-83-6 Clinical Trial | 141136-83-6 Route of Synthesis | 141136-83-6 storage condition | 141136-83-6 diseases and conditions | 141136-83-6 flash point | 141136-83-6 boiling point | 141136-83-6 melting point | 141136-83-6 storage condition | 141136-83-6 brand