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62893-20-3 (Cefoperazone sodium)

1

Identification

Cefoperazone sodium Cefoperazone sodium
Name Cefoperazone sodium
Formula C25H26N9NaO8S2
MW 667.65
CAS No. 62893-20-3
EINECS 263-751-5
Smiles O=C(C(N12)=C(CSC3=NN=NN3C)CS[[email protected]]2([H])[[email protected]](NC(C(NC(N4C(C(N(CC)CC4)=O)=O)=O)C5=CC=C(O)C=C5)=O)C1=O)[O-].[Na+]
Synonyms [6R-[6alpha,7beta(R*)]]-7-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-car; sodium (6R,7R)-7-(2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChI InChI=1S/C25H27N9O8S2.Na/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2;/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41);/q;+1/p-1/t15?,16-,22-;/m1./s1
2

Introduction

Background Information

Cefoperazone Sodium is a third generation cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM, used in the treatment of bacterial infections caused by susceptible microorganisms. ......by BOC Sciences
Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It has been proposed especially against Pseudomonas infections. ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance: EBNumber:EB000051958

Storage condition

Solubility

50 mg/mL in H2O by CHEMSCENE, LLC
50 mg/mL in H2O by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways Anti-infection
Target Bacterial
Research Area Infection
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Cefoperazone sodium - Launched
7

Safety Data of Cefoperazone sodium

Hazard Symbols : Xn
Risk Statements : R42/43
Safety Statements : S22;S36/37
HS Code : 29419000
RTECS : XI0374000
WGKGermany : 2
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Abcam 1g/USD73();5g/USD222() USA
Aladdin 1g/RMB358();5g/RMB1369() China
Alfa Chemistry USA
Apollo Scientific Ltd. United Kingdom
BOC Sciences
Biochempartner Co., Ltd China
Biomol GmbH Germany
CHEMSCENE, LLC 1g/USD67();5g/USD199() USA
Cayman Chemical Company 1g/USD39();5g/USD156();10g/USD254() USA
Clearsynth Labs Limited 25mg/USD100();50mg/USD150() India
Dawnrays Pharmaceutical (Holdings) Ltd. China
Hangzhou Fushitang Biology Technology Co., Ltd. China
MAYA-R 1g/RMB392();5g/RMB1372() China
MedChemexpress Co., Ltd. 1g/USD67();5g/USD199() USA
Santa Cruz Biotechnology, Inc. 1g/USD55();5g/USD188() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 1g/USD67();5g/USD199() China
Shanghai Mijiang Chemical Co., Ltd. China
Shanghai Pharmarketech Co., Ltd. China
Sigma-Aldrich, Inc. 1g/USD59();5g/USD204() USA
Spectrum Chemical Mfg. Corp. 5kg/USD6467() USA
Target Molecule Corp. 10mg/USD20();50mg/USD75();100mg/USD132() USA
Toronto Research Chemicals Inc. 1g/USD50();2g/USD75();5g/USD120();10g/USD175();25g/USD295() Canada
Zhejiang Ouhua Chemical Imp. & Exp. Co., Ltd. China
Zhuhai Sanxin Fine Chemical Co., Ltd. China
10

Related Products

Other Forms of 62893-20-3

Name CAS No Formula MW
Cefoperazone 62893-19-0 C25H27N9O8S2 645.67

Recommended Compounds in Bacterial

Name CAS No Formula MW
Fidaxomicin 873857-62-6 C52H74Cl2O18 1058.04
AVX 13616 900814-48-4 C50H73Cl2N7O7 955.06
Bedaquiline (fumarate) 845533-86-0 C36H35BrN2O6 671.58
Mafenide (Acetate) 13009-99-9 C9H14N2O4S 246.28
Cefozopran 113359-04-9 C19H17N9O5S2 515.53
Azithromycin 83905-01-5 C38H72N2O12 748.9845
Pazufloxacin 127045-41-4 C16H15FN2O4 318.3
Pazufloxacin (mesylate) 163680-77-1 C17H19FN2O7S 414.4054
Capreomycin (sulfate) 1405-37-4 C24H44N14O12S 752.76
Bleomycin (sulfate) 9041-93-4 C110H168N34O46S7 2927.17
G-418 (disulfate) 108321-42-2 C20H44N4O18S2 692.71
Demeclocycline (hydrochloride) 64-73-3 C21H22Cl2N2O8 501.31
Apramycin 37321-09-8 C21H41N5O11 539.58
Ceftriaxone 73384-59-5 C18H18N8O7S3 554.58
Ceftibuten 97519-39-6 C15H14N4O6S2 410.42
Dapsone 80-08-0 C12H12N2O2S 248.3
Vancomycin 1404-90-6 C66H76Cl3N9O24 1485.72
Lomefloxacin 98079-51-7 C17H19F2N3O3 351.35
Dirithromycin 62013-04-1 C42H78N2O14 835.07
Cefepime (Dihydrochloride Monohydrate) 123171-59-5 C19H28Cl2N6O6S2 571.5

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Cefoperazone sodium

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