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96-98-0 (4-Methyl-3-nitrobenzoic acid)

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Identification

4-Methyl-3-nitrobenzoic acid 4-Methyl-3-nitrobenzoic acid
Name 4-Methyl-3-nitrobenzoic acid
Formula C8H7NO4
MW 181.15
CAS No. 96-98-0
EINECS 202-549-3
Smiles CC1=C([N+]([O-])=O)C=C(C(O)=O)C=C1
Synonyms 3-Nitro-4-methylbenzoic acid; 3-Nitro-p-toluic acid; 4-methyl-3-nitrobenzoic acid
InChI InChI=1S/C8H7NO4/c1-5-2-3-6(8(10)11)4-7(5)9(12)13/h2-4H,1H3,(H,10,11)
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Introduction

Prismatic crystals or off-white powder.

Background Information

MNBA, also known as 4-methyl-3-nitro-benzoic acid, is a potential cell migration inhibitor, with potential anticancer activity. T reatment with MNBA on breast cancer cells can inhibit EGF-induced migration and chemotaxis in vitro. In vivo assay demonstrated that MNBA and Paclitaxel synergistically inhibited tumor growth and metastasis in breast cancer SCID mice xenografts. These results suggest that MNBA is a potent inhibitor cancer cell chemotaxis and may be developed into a novel anti-metastasis drug . (source: Cancer Lett. 2011 Jun 1;305(1):69-75. doi: 10.1016/j.canlet.2011.02.028. Epub 2011 Mar 22.). ......by MedKoo Biosciences, Inc.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000030445

Storage condition

Solubility

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Mechanism and Indication

Signaling Pathways
Target
Research Area
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
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Safety Data of 4-Methyl-3-nitrobenzoic acid

´╗┐Hazard Symbols : Xn
´╗┐Risk Statements : R20/21/22;R36/37/38
Safety Statements : S22;S26;S36/37/39
WGKGermany : 1
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Spectral Information

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Suppliers List

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Related Products

Other Forms of 96-98-0

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Recommended Compounds in

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Recommended Compounds in Same Indication

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Route of Synthesis

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References

Protocol Reference

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More Information

4-Methyl-3-nitrobenzoic acid

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