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57-91-0 (alpha-Estradiol)

1

Identification

alpha-Estradiol alpha-Estradiol
Name alpha-Estradiol
Formula C18H24O2
MW 272.382
CAS No. 57-91-0
EINECS 200-354-8
Smiles C[[email protected]@]12[[email protected]](O)CC[[email protected]@]1([H])[[email protected]]3([H])CCC4=C(C=CC(O)=C4)[[email protected]@]3([H])CC2
Synonyms Alfatradiol; Epiestradiol; Epiestrol
InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1
2

Introduction

Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.

Background Information

Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia. ......by MedChemexpress Co., Ltd.
Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively). β-Estradiol also available. ......by Tocris Bioscience Inc.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:white with slight yellow cast EBNumber:EB000029319

Storage condition

Store at RT by Tocris Bioscience Inc.

Solubility

Soluble to 100 mM in DMSO and to 100 mM in ethanol by Tocris Bioscience Inc.
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Mechanism and Indication

Signaling Pathways
Target
Research Area
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
alpha-Estradiol - No Development Reported
7

Safety Data of alpha-Estradiol

Hazard Symbols : Xn
Risk Statements : R40;R48
Safety Statements : S22;S24/25
Transport Information : UN 2811
RTECS : KG3750000
WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
BOC Sciences
CHEMSCENE, LLC 100mg/USD60();500mg/USD100() USA
Cayman Chemical Company USA
China Jintai Biocompound Company China
Easternchem Company Limited China
MedChemexpress Co., Ltd. 100mg/USD60();500mg/USD100() USA
Pure Chemistry Scientific Inc. 1g/USD43(In stock) USA
Sequoia Research Products Ltd.
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD60();500mg/USD100() China
Taizhou Crene Biotechnology Co., Ltd. China
Tocris Bioscience Inc. USA
10

Related Products

Other Forms of 57-91-0

Name CAS No Formula MW
Estradiol 50-28-2 C18H24O2 272.38

Recommended Compounds in

Name CAS No Formula MW

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

12

References

Protocol Reference

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More Information

alpha-Estradiol

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