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93129-94-3 (Tacalcitol (monohydrate))

1

Identification

Tacalcitol (monohydrate) Tacalcitol (monohydrate)
Name Tacalcitol (monohydrate)
Formula C27H46O4
MW 434.65
CAS No. 93129-94-3
EINECS
Smiles CC([[email protected]@H](CC[[email protected]]([[email protected]@H](CC[[email protected]]1/2[H])[[email protected]@]1(C)CCCC2=C/C=C3C[[email protected]@H](C[[email protected]](C/3=C)O)O)C)O)C.[H]O[H]
Synonyms 1,24(R)-Dihydroxyvitamin D3, monohydrate; (1S,3R,Z)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R)-5-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol hydrate
InChI InChI=1S/C27H44O3.H2O/c1-17(2)25(29)13-8-18(3)23-11-12-24-20(7-6-14-27(23,24)5)9-10-21-15-22(28)16-26(30)19(21)4;/h9-10,17-18,22-26,28-30H,4,6-8,11-16H2,1-3,5H3;1H2/b20-9+,21-10-;/t18-,22+,23-,24+,25-,26-,27-;/m1./s1
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Introduction

Tacalcitol monohydrate (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium. IC50 value: Target: Tacalcitol modulates immunological and inflammatory processes.

Background Information

Tacalcitol monohydrate promotes normal bone development by regulating calcium. ......by AdooQ BioScience, LLC
Tacalcitol monohydrate is a VDR-like Receptor promotes normal bone development by regulating calcium. It modulates immunological and inflammatory processes and induces nerve growth factor production in epidermal keratinocytes. ......by BOC Sciences
Tacalcitol monohydrate is is a D3 derivative, a VDR-like receptor promotes normal bone development by regulating calcium. ......by MedKoo Biosciences, Inc.
A synthetic vitamin D3 analog that usually prescribed by a general practitioner or dermatologist for the treatment of psoriasis, chronic chapped lips and other severe dry skin conditions.PsoriasisApproved ......by ProbeChem
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000028766

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Others
Target VD/VDR
Research Area Others
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Tacalcitol (monohydrate) - Launched
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Safety Data of Tacalcitol (monohydrate)

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
AdooQ BioScience, LLC USA
Ark Pharm, Inc. USA
BOC Sciences
CHEMSCENE, LLC 1mg/USD370();5mg/USD1188() USA
MedChemexpress Co., Ltd. 1mg/USD370();5mg/USD1188() USA
MedKoo Biosciences, Inc. USA
ProbeChem
Shanghai Haoyuan Chemexpress Co., Ltd. 1mg/USD370();5mg/USD1188() China
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Related Products

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Route of Synthesis

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References

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More Information

Tacalcitol (monohydrate)

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