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143032-85-3 (1alpha-Hydroxy VD4)

1

Identification

1alpha-Hydroxy VD4 1alpha-Hydroxy VD4
Name 1alpha-Hydroxy VD4
Formula C28H46O2
MW 414.66
CAS No. 143032-85-3
EINECS
Smiles C=C1[[email protected]@H](O)C[[email protected]](O)C/C1=C/C=C2[[email protected]@](CC[[email protected]@H]3[[email protected]](C)CC[[email protected]](C)C(C)C)([H])[[email protected]]3(C)CCC/2
Synonyms 1α-Hydroxy vitamin D4; (1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5S)-5,6-dimethylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
InChI InChI=1S/C28H46O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h11-12,18-20,24-27,29-30H,5,7-10,13-17H2,1-4,6H3/b22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1
2

Introduction

1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.

Background Information

1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative,  can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. ......by BOC Sciences
1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. IC50 value; Target: VD analog ......by MedChemexpress Co., Ltd.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white solid EBNumber:EB000023523

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways Others
Target VD/VDR
Research Area Cancer
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
1alpha-Hydroxy VD4 - Not Found
1alpha-Hydroxy VD4 - No Development Reported
7

Safety Data of 1alpha-Hydroxy VD4

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Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AdooQ BioScience, LLC 1mg/USD700() USA
Apexbio Technology LLC 1mg/USD822() USA
BOC Sciences
CHEMSCENE, LLC 1mg/USD880(In stock) USA
Chemvon Biotechnology Co., Ltd CHINA
MedChemexpress Co., Ltd. 1mg/USD880(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 1mg/USD880(Get quote) China
10

Related Products

Other Forms of 143032-85-3

Name CAS No Formula MW

Recommended Compounds in VD/VDR

Name CAS No Formula MW
25,26-Dihydroxyvitamin D3 29261-12-9 C27H44O3 416.64
(24R)-MC 976 112828-09-8 C27H42O3 414.62
(24S)-24,25-Dihydroxyvitamin D3 55700-58-8 C27H44O3 416.64
Impurity D of Calcitriol 103656-40-2 C28H46O3 430.66
Calcifediol (monohydrate) 63283-36-3 C27H44O2 400.64
Cholecalciferol 67-97-0 C27H44O 384.64
(24S)-MC 976 112849-14-6 C27H42O3 414.62
(1S,4R,E)-4-((1R,3aS,7aR,E)-4-((Z)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-ol 112875-61-3 C39H68O3Si2 641.13
VD3-D6 118584-54-6 C27H38D6O 390.67
VD2-D3 1217448-46-8 C28H41D3O 399.67
25-Hydroxy VD2-D6 1262843-46-8 C28H38D6O2 418.68
1alpha, 25-Dihydroxy VD2-D6 216244-04-1 C28H38D6O3 434.68
Calcipotriol (monohydrate) 147657-22-5 C27H42O4 430.62
Vitamin D4 511-28-4 C27H44O 384.64
(1R,3S,E)-5-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 73837-24-8 C27H44O3 416.64
(1R,3S,E)-5-((E)-2-((1R,3aR,7aR)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 113082-99-8 C27H40O3 412.6
Paricalcitol 131918-61-1 C27H44O3 416.64
MC 976 129831-99-8 C27H42O3 414.62
24R-Calcipotriol 112827-99-3 C27H40O3 412.6
MC 1046 126860-83-1 C27H38O3 410.59

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

1alpha-Hydroxy VD4

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