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916170-19-9 (AC-55541)

1

Identification

AC-55541 AC-55541
Name AC-55541
Formula C25H20BrN5O3
MW 518.362
CAS No. 916170-19-9
EINECS
Smiles O=C(NC(C(C1=CC=CC=C12)=NNC2=O)C(N/N=C(C)/C3=CC=CC(Br)=C3)=O)C4=CC=CC=C4
Synonyms
InChI InChI=1S/C25H20BrN5O3/c1-15(17-10-7-11-18(26)14-17)28-31-25(34)22(27-23(32)16-8-3-2-4-9-16)21-19-12-5-6-13-20(19)24(33)30-29-21/h2-14,22H,1H3,(H,27,32)(H,30,33)(H,31,34)/b28-15+
2

Introduction

Background Information

AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist which displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. It activated PAR2 signaling in cellular proliferation a ......by BOC Sciences
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000023358

Storage condition

4°C by MedChemexpress Co., Ltd.

Solubility

DMSO 50 mg/ml by CHEMSCENE, LLC
DMSO 50 mg/ml by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways GPCR/G Protein
Target Protease-Activated Receptor (PAR)
Research Area Others
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
AC-55541 - Not Found
AC-55541 - No Development Reported
7

Safety Data of AC-55541

8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Apexbio Technology LLC 10mg/USD165(Ship Within 7 Days);50mg/USD680(Ship Within 7 Days) USA
BOC Sciences
BioVision, Inc., 5mg/USD85() USA
Biochempartner Co., Ltd China
CHEMSCENE, LLC 5mg/USD96();10mg/USD168() USA
Cayman Chemical Company 1mg/USD35() USA
DC Chemicals 100mg/USD450(In stock) China
KareBay Biochem 50mg/USD700() USA
MedChemexpress Co., Ltd. 5mg/USD96();10mg/USD168() USA
Santa Cruz Biotechnology, Inc. 5mg/USD132() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5mg/USD96();10mg/USD168() China
Target Molecule Corp. 10mg/USD135();25mg/USD218();50mg/USD328() USA
Tocris Bioscience Inc. 10mg/USD195() USA
eNovation Chemicals LLC 25mg/USD358() USA
10

Related Products

Other Forms of 916170-19-9

Name CAS No Formula MW

Recommended Compounds in Protease-Activated Receptor (PAR)

Name CAS No Formula MW
Vorapaxar 618385-01-6 C29H33FN2O4 492.58
TRAP-6 141136-83-6 C34H56N10O9 748.87
TFLLR-NH2 197794-83-5 C31H53N9O6 647.81
Protease-Activated Receptor-2, amide C28H54N8O7 614.8
Protease-Activated Receptor-4 C33H46N8O7 666.77

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

AC-55541

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