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112827-99-3 (24R-Calcipotriol)

1

Identification

24R-Calcipotriol 24R-Calcipotriol
Name 24R-Calcipotriol
Formula C27H40O3
MW 412.6
CAS No. 112827-99-3
EINECS
Smiles C[[email protected]]1(CCC/2)C(C2=CC=C3C[[email protected]@H](O)C[[email protected]](O)C3=C)CC[[email protected]@H]1[[email protected]](C)/C=C[[email protected]](C4CC4)O
Synonyms PRI 2202; Impurity D of Calcipotriol; (1R,3S,Z)-5-((E)-2-((1R,7aR)-1-((2R,5S,Z)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
InChI InChI=1S/C27H40O3/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23,24)3)7-10-21-15-22(28)16-26(30)18(21)2/h6-7,10,13,17,20,22-26,28-30H,2,4-5,8-9,11-12,14-16H2,1,3H3/b13-6-,19-7+,21-10-/t17-,22-,23-,24?,25-,26+,27-/m1/s1
2

Introduction

24R-Calcipotriol(PRI 2202) is impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a VDR-like Receptors.

Background Information

24R-Calcipotriol is an impurity of Calcipotriol, which is a ligand of VDR-like receptors. ......by BOC Sciences
24R-Calcipotriol(PRI 2202) is impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a VDR-like Receptors. IC50 value: Target: Vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; Calcipotriol (MC 903; Calcipotriene) exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25 and mouse WEHI-3 cancer cell lines. ......by MedChemexpress Co., Ltd.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000022522

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Others
Target VD/VDR
Research Area Cancer
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
24R-Calcipotriol - Not Found
24R-Calcipotriol - No Development Reported
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Safety Data of 24R-Calcipotriol

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
Apexbio Technology LLC 1mg/USD510() USA
BOC Sciences
CHEMSCENE, LLC USA
Clearsynth Labs Limited 25mg/USD2500() India
MedChemexpress Co., Ltd. 1mg/USD510(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 1mg/USD510(In stock) China
10

Related Products

Other Forms of 112827-99-3

Name CAS No Formula MW

Recommended Compounds in VD/VDR

Name CAS No Formula MW
25,26-Dihydroxyvitamin D3 29261-12-9 C27H44O3 416.64
(24R)-MC 976 112828-09-8 C27H42O3 414.62
(24S)-24,25-Dihydroxyvitamin D3 55700-58-8 C27H44O3 416.64
Impurity D of Calcitriol 103656-40-2 C28H46O3 430.66
Calcifediol (monohydrate) 63283-36-3 C27H44O2 400.64
Cholecalciferol 67-97-0 C27H44O 384.64
(24S)-MC 976 112849-14-6 C27H42O3 414.62
(1S,4R,E)-4-((1R,3aS,7aR,E)-4-((Z)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-ol 112875-61-3 C39H68O3Si2 641.13
VD3-D6 118584-54-6 C27H38D6O 390.67
VD2-D3 1217448-46-8 C28H41D3O 399.67
25-Hydroxy VD2-D6 1262843-46-8 C28H38D6O2 418.68
1alpha, 25-Dihydroxy VD2-D6 216244-04-1 C28H38D6O3 434.68
Calcipotriol (monohydrate) 147657-22-5 C27H42O4 430.62
Vitamin D4 511-28-4 C27H44O 384.64
(1R,3S,E)-5-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 73837-24-8 C27H44O3 416.64
(1R,3S,E)-5-((E)-2-((1R,3aR,7aR)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 113082-99-8 C27H40O3 412.6
Paricalcitol 131918-61-1 C27H44O3 416.64
MC 976 129831-99-8 C27H42O3 414.62
MC 1046 126860-83-1 C27H38O3 410.59
3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 163018-26-6 C30H51NO2 457.73

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

13

More Information

24R-Calcipotriol

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