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96946-42-8 (Cisatracurium (besylate))



Cisatracurium (besylate) Cisatracurium (besylate)
Name Cisatracurium (besylate)
Formula C65H82N2O18S2
MW 1243.48
CAS No. 96946-42-8
Smiles O=C(OCCCCCOC(CC[[email protected]+]1(C)[[email protected]](CC2=CC=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)CC1)=O)CC[[email protected]+]4(C)[[email protected]](CC5=CC=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4.O=S(C7=CC=CC=C7)([O-])=O.O=S(C8=CC=CC=C8)([O-])=O
Synonyms Nimbex; (1R,1'R,2R,2'R)-2,2'-((pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium) benzenesulfonate
InChI InChI=1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2/t42-,43-,54-,55-;;/m1../s1


Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. Target: AChR alpha-2 Cisatracurium is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Background Information

An enantiomer of Atracurium Besylate (A794500). A neuromuscular blocking agent. It could be used in liver transplant patient with safety. ......by BOC Sciences
Cisatracurium (formerly recognized as 51W89, and marketed as Nimbex) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is a bisbenzyltetrahydroisoquinolinium agent with an intermediate duration of action. Cisatracurium is one of the ten isomers of the parent molecule, atracurium. Moreover, cisatracurium represents approximately 15% of the atracurium mixture. ......by MedKoo Biosciences, Inc.
Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium Besylate acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine. The neuromuscular block produced by cisatracurium besylate is readily antagonized by anticholinesterase agents once recovery has started. As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at the time of reversal, the longer the time required for recovery of neuromuscular function. Compared to other neuromuscular blocking agents, it is intermediate in its onset and duration of action. ......by Target Molecule Corp.

Protocol(Only for Reference)

Cell Experiment

Animal Experiment


Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000016519

Storage condition


DMSO 250 mg/mL; Water 48 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 249 mg/mL (200.24 mM); Ethanol249 mg/mL (200.24 mM); Water47 mg/mL (37.79 mM) by Selleck Chemicals LLC

Mechanism and Indication


Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Cisatracurium (besylate) - Launched

Safety Data of Cisatracurium (besylate)

Hazard Symbols : T
Risk Statements : 25-36
Safety Statements : 45

Spectral Information


Suppliers List

Company Price and Availability Country/Region
Ark Pharm, Inc. USA
BOC Sciences 250mg/USD169(In stock)
Beijing Eagle Sky Pharmatech Co., Ltd. China
Beijing Lang Rebone Technology Co., Ltd. China
Biochempartner Co., Ltd China
CHEMSCENE, LLC 100mg/USD397();500mg/USD1543() USA
Cayman Chemical Company USA
Clearsynth Labs Limited 25mg/USD100() India
Dongying MaiDiSen Biotechnology Research Institute China
Lianyungang Guike Pharmaceutical Co., ltd. China
MedChemexpress Co., Ltd. 100mg/USD397();500mg/USD1543() USA
MedKoo Biosciences, Inc. USA
Santa Cruz Biotechnology, Inc. 100mg/USD300() USA
Selleck Chemicals LLC 25mg/USD110(In stock);10mM/1mLIn DMSO/USD140(In stock);10mM(in 1mL DMSO)/USD176(in 1mL DMSO);100mg/USD370(In stock) USA
Shandong Boyuan Pharmaceutical Co., Ltd. China
Shandong Kingnod Pharmaceuticals Co., Ltd. China
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD397();500mg/USD1543() China
Sigma-Aldrich, Inc. 10mg/USD176() USA
Target Molecule Corp. 10mg/USD43();25mg/USD74();50mg/USD133() USA
Zhejiang Haisen Pharmaceutical Co., Ltd CHINA

Related Products

Other Forms of 96946-42-8

Name CAS No Formula MW

Recommended Compounds in nAChR Autophagy

Name CAS No Formula MW
L-Nicotine 54-11-5 C10H14N2 162.23
Decamethonium (Bromide) 541-22-0 C16H38Br2N2 418.29
Hexamethonium (Bromide) 55-97-0 C12H30Br2N2 362.19
Meclofenoxate (hydrochloride) 3685-84-5 C12H17Cl2NO3 294.17
Pancuronium (dibromide) 15500-66-0 C35H60Br2N2O4 732.67
Adiphenine (hydrochloride) 50-42-0 C20H26ClNO2 347.88
Atracurium (besylate) 64228-81-5 0.0
Vecuronium (bromide) 50700-72-6 C34H57BrN2O4 637.73
Catharanthine 2468-21-5 C21H24N2O2 336.43
Vinblastine 865-21-4 C46H58N4O9 810.97
EVP-6124 (hydrochloride) 550999-74-1 C16H18Cl2N2OS 357.3
EVP-6124 550999-75-2 C16H17ClN2OS 320.84
ABT 894 799279-80-4 C10H11Cl2N3 244.12
Monepantel 887148-69-8 C20H13F6N3O2S 473.39
GTS-21 148372-04-7 C19H20N2O2 308.37
ZSET1446 887603-94-3 C15H12N2O 236.2686
Aniracetam 72432-10-1 C12H13NO3 219.24
CP-810123 439608-12-5 C14H18N4O 258.32
Varenicline (Tartrate) 375815-87-5 C17H19N3O6 361.35
Varenicline (Hydrochloride) 230615-23-3 C13H14ClN3 247.72

Recommended Compounds in Same Indication

Name CAS No Formula MW

Route of Synthesis




More Information

Cisatracurium (besylate)

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