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130693-82-2 (Dorzolamide (hydrochloride))

1

Identification

Dorzolamide (hydrochloride) Dorzolamide (hydrochloride)
Name Dorzolamide (hydrochloride)
Formula
MW 0.0
CAS No. 130693-82-2
EINECS
Smiles
Synonyms (2S,4S)-2-Ethylamino-4-methyl-5,5-dioxo-5,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide hydrochloride;
InChI
2

Introduction

Dorzolamide Hcl(L671152 Hcl; MK507 Hcl) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor. Target: carbonic anhydrase (CA) Dorzolamide hydrochloride is a carbonic anhydrase inhibitor.

Background Information

Dorzolamide is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour. ......by BOC Sciences
Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. ......by Selleck Chemicals LLC
Dorzolamide is a carbonic anhydrase (CA) inhibitor. It is used in ophthalmic solutions (Trusopt) to lower intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000016403

Storage condition

Solubility

DMSO <1 mg/Ml; Water 14 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro Water 14 mg/mL (38.79 mM); DMSO<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways Metabolic Enzyme/Protease
Target Carbonic Anhydrase
Research Area Others
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Dorzolamide (hydrochloride) - Launched
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Safety Data of Dorzolamide (hydrochloride)

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
A5 Pharma Tech Co., Ltd. China
BOC Sciences
CHEMSCENE, LLC 10mg/USD70();50mg/USD110() USA
China Jintai Biocompound Company China
MedChemexpress Co., Ltd. 10mg/USD70();50mg/USD110() USA
Qingdao Kingway Pharmtech Co., Ltd. China
Selleck Chemicals LLC 10mg/USD110(In stock);25mg/USD170(In stock);100mg/USD470(In stock) USA
Shanghai Amadis Bio-Technology Co., Ltd CHINA
Shanghai Haoyuan Chemexpress Co., Ltd. 10mg/USD70();50mg/USD110() China
Shanghai MOF Chemical Tech Limited China
Taizhou Apler Chemical Industry Co., Ltd. China
Taizhou Crene Biotechnology Co., Ltd. China
Target Molecule Corp. 10mg/USD85();25mg/USD125();50mg/USD198();100mg/USD291() USA
Yitai Pharmatech Co., Ltd. China
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Related Products

Other Forms of 130693-82-2

Name CAS No Formula MW
Dorzolamide (hydrochloride) 130693-82-2 C10H17ClN2O4S3 360.901

Recommended Compounds in Carbonic Anhydrase

Name CAS No Formula MW
Brinzolamide 138890-62-7 C12H21N3O5S3 383.51
Methyclothiazide 135-07-9 C9H11Cl2N3O4S2 360.24
Methazolamide 554-57-4 C5H8N4O3S2 236.27
Tioxolone 4991-65-5 C7H4O3S 168.17
Dichlorphenamide 120-97-8 C6H6Cl2N2O4S2 305.16
Dorzolamide (hydrochloride) 130693-82-2 C10H17ClN2O4S3 360.901
Dimethylfraxetin 6035-49-0 C12H12O5 236.2207
U-104 178606-66-1 C13H12FN3O3S 309.32
Acetazolamide 59-66-5 C4H6N4O3S2 222.25
Acetazolamide D3 1189904-01-5 C4H3D3N4O3S2 225.26
Dorzolamide 120279-96-1 C10H16N2O4S3 324.44

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Dorzolamide (hydrochloride)

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