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10212-25-6 (Ancitabine (hydrochloride))

1

Identification

Ancitabine (hydrochloride) Ancitabine (hydrochloride)
Name Ancitabine (hydrochloride)
Formula C9H12ClN3O4
MW 261.6623
CAS No. 10212-25-6
EINECS 233-515-6
Smiles OC[[email protected]@H]1[[email protected]@H](O)[[email protected]@](O2)([H])[[email protected]@](N(C2=N3)C=CC3=N)([H])O1.[H]Cl JjbwQ0byOjHpJ4gXWRYObRsaR41DaP==
Synonyms Cyclocytidine hydrochloride;Cyclo-CMP hydrochloride;Cyclo-C
InChI InChI=1S/C9H11N3O4.ClH/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8;/h1-2,4,6-8,10,13-14H,3H2;1H/t4-,6-,7+,8-;/m1./s1
2

Introduction

Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.

Background Information

2,2'-Anhydro-cytidine-HCl is a DNA synthesis inhibitor commonly used as an antineoplastic agent to treat leukemias. ......by BOC Sciences
Ancitabine HCl is a pyrimidine analog and DNA synthesis inhibitor previously used to treat leukemias. It inhibits proliferation of HSV-1 and CMV and induces degranulation of granular tubes. ......by MedKoo Biosciences, Inc.
Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia. ......by Selleck Chemicals LLC
Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000015555

Storage condition

Store in a tightly closed container, in a cool and dry place. by MedChemexpress Co., Ltd.

Solubility

10 mM in DMSO by CHEMSCENE, LLC
10 mM in DMSO by MedChemexpress Co., Ltd.
DMSO mg/mL (<1 mM) ; Water mg/mL (<1 mM) ; Ethanol mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways Autophagy
Target Autophagy
Research Area Cancer
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Ancitabine (hydrochloride) - Not Found
Ancitabine (hydrochloride) - No Development Reported
7

Safety Data of Ancitabine (hydrochloride)

Safety Statements : S24/25
RTECS : LV2615000
WGKGermany : 2
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AA Blocks LLC
Abblis Chemicals LLC 1g/USD81();5g/USD302() USA
Aladdin 1g/RMB384();5g/RMB1182() China
Ark Pharm, Inc. 1g/USD48();5g/USD148() USA
BLD Pharmatech
BOC Sciences
Biocaxis Chemicals Co., Ltd. China
Biochempartner Co., Ltd China
CHEMSCENE, LLC 200mg/USD60();1g/USD84() USA
Carbosynth Limited 2g/USD70();5g/USD125();10g/USD210();25g/USD325();50g/USD450()
Fluorochem United Kingdom
Hangzhou Neway Chemicals Co., Ltd. China
Hanhong Chemicals 500g/RMB1008();1kg/RMB1663() China
MAYA-R 1g/RMB690();5g/RMB1850() China
MedChemexpress Co., Ltd. 200mg/USD60();1g/USD84() USA
MedKoo Biosciences, Inc. USA
Santa Cruz Biotechnology, Inc. 1g/USD70() USA
Selleck Chemicals LLC 200mg/USD70(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 200mg/USD60();1g/USD84() China
Shanghai Qiuzhiyou Bioscience &amp; Biotechnology Co., Ltd CHINA
Sigma-Aldrich, Inc. 1g/USD72() USA
Target Molecule Corp. 5mg/USD20();25mg/USD78();100mg/USD174();200mg/USD312() USA
Tianjin Heowns Biochemical Technology Co., Ltd. 1g/RMB398();5g/RMB1108() China
Tokyo Chemical Industry Co., Ltd. 1g/USD49();5g/USD148() Japan
Xiamen Amoipharm Chemicals Co., Ltd. China
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Related Products

Other Forms of 10212-25-6

Name CAS No Formula MW
Ancitabine 31698-14-3 C9H11N3O4 225.2

Recommended Compounds in Autophagy

Name CAS No Formula MW
Pirarubicin (Hydrochloride) 95343-20-7 C32H38ClNO12 664.1
Berberine (chloride) 633-65-8 C20H18ClNO4 371.8142
DMH-1 1206711-16-1 C24H20N4O 380.44
CB-839 1439399-58-2 C26H24F3N7O3S 571.57
H-89 (dihydrochloride) 130964-39-5 C20H22BrCl2N3O2S 519.2826
Shikonin 517-89-5 C16H16O5 288.3
H 89 127243-85-0 C20H20BrN3O2S 446.36
Eupatilin 22368-21-4 C18H16O7 344.32
Isoalantolactone 470-17-7 C15H20O2 232.32
Scutellarein 529-53-3 C15H10O6 286.24
Leonurine 24697-74-3 C14H21N3O5 311.33
Berbamine (dihydrochloride) 6078-17-7 C37H42Cl2N2O6 681.6452
Ruxolitinib (S enantiomer) 941685-37-6 C17H18N6 306.37
D-Glucosamine (Hydrochloride) 66-84-2 C6H14ClNO5 215.63
Schizandrin A 61281-38-7 C22H28O6 388.45
Schisandrol B 58546-54-6 C23H28O7 416.46
Schisandrol A 7432-28-2 C24H32O7 432.51
Icaritin 118525-40-9 C21H20O6 368.3799
Bicyclol 118159-48-1 C19H18O9 390.34
Azithromycin 83905-01-5 C38H72N2O12 748.9845

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Ancitabine (hydrochloride)

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