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521-61-9 (Physcion)



Physcion Physcion
Name Physcion
Formula C16H12O5
MW 284.2635
CAS No. 521-61-9
EINECS 208-315-7
Smiles O=C1C2=C(C=C(C)C=C2O)C(C3=CC(OC)=CC(O)=C13)=O
Synonyms Parietin
InChI InChI=1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3


Physcion is an anthraquinone from roots of Rheum officinale Baill.

Background Information

Natural inducer of apoptosis and autophagy in human nasopharyngeal carcinoma, inhibiting 6-phosphogluconate dehydrogenase (6PGD) ......by AOBIOUS INC
Rheochrysidin is one of the major components of Da-Cheng-Qi decoction used in the treatment of inflammation. ......by AdooQ BioScience, LLC
Physcion is an anthraquinone isolated from Rheum emodi. An anthraquinone originally isolated from Rheum emodi. Physcion can be used to study antibiotics, antifungals, bioactive small molecules and cell biology. Physcion has been used in a study to test the cytotoxicity of juglanthraquinone C on human cancer cells. Physcion has also been used in a study that investigated the metabolic regulatory effects of Rheum undulatum in a high-fat diet model. ......by Affix Scientific
Physcion is an anthraquinone from roots of Rheum officinale Baill.It has also shown anti-fungal activity against barley powdery mildew and cucumber powdery mildew, more efficiently in the latter case than treatments with fenarimol and polyoxin B. ......by BOC Sciences
Physcion, also known as, 6-O-methyl Emodin; NSC 251670, is a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinoma. Physcion inhibits the metastatic potential of human colorectal cancer SW620 cells in vitro by suppressing the transcription factor SOX2. Physcion induces mitochondria-driven apoptosis in colorectal cancer cells via downregulating EMMPRIN. ......by MedKoo Biosciences, Inc.
Physcion is an anthraquinone from roots of Rheum officinale Baill. ......by Selleck Chemicals LLC
Physcion is an anthraquinone from roots of Rheum officinale Baill. ......by Target Molecule Corp.

Protocol(Only for Reference)

Cell Experiment

Animal Experiment


Physical and Chemical Properties

Appearance: EBNumber:EB000015540

Storage condition

Up to one week at 4°C or six months at -20°C. by Affix Scientific


Water by Affix Scientific
(25°C) * In vitro DMSO 1 mg/mL warming (3.51 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) by Selleck Chemicals LLC

Mechanism and Indication

Signaling Pathways
Research Area

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Physcion - No Development Reported

Safety Data of Physcion

Hazard Symbols : Xi
Risk Statements : R36/37/38
Safety Statements : S26
RTECS : CB6720000
WGKGermany : 3

Spectral Information


Suppliers List


Related Products

Other Forms of 521-61-9

Name CAS No Formula MW

Recommended Compounds in

Name CAS No Formula MW

Recommended Compounds in Same Indication

Name CAS No Formula MW

Route of Synthesis



Protocol Reference


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