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10338-51-9 (Salidroside)

1

Identification

Salidroside Salidroside
Name Salidroside
Formula C14H20O7
MW 300.3
CAS No. 10338-51-9
EINECS
Smiles O[[email protected]]1[[email protected]](OCCC2=CC=C(O)C=C2)O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]1O
Synonyms Rhodioloside; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenethoxy)tetrahydro-2H-pyran-3,4,5-triol
InChI InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1
2

Introduction

Salidroside is a prolyl endopeptidase Inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling.

Background Information

Salidroside (Rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea. It is thought to be one of the compounds responsible for the antidepressant and anxiolytic actions of this plant, along with rosavin. ......by AdooQ BioScience, LLC
Salidroside is a prolyl endopeptidase Inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. ......by MedChemexpress Co., Ltd.
Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. ......by Selleck Chemicals LLC
Bottomless glass bottle. Contents are inside inserted fused cone. ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance: EBNumber:EB000015539

Storage condition

Solubility

10 mM in DMSO by CHEMSCENE, LLC
10 mM in DMSO by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 60 mg/mL (199.8 mM); Water60 mg/mL (199.8 mM); Ethanol4 mg/mL (13.32 mM) by Selleck Chemicals LLC
5

Mechanism and Indication

Signaling Pathways PI3K/Akt/mTOR Epigenetics
Target mTOR AMPK
Research Area Others
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Salidroside - Not Found
Salidroside - No Development Reported
7

Safety Data of Salidroside

Hazard Symbols : Xi
Risk Statements : 36
Safety Statements : 26
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AOBIOUS INC USA
Adipogen Corporation USA
AdooQ BioScience, LLC USA
Aladdin 20mg/RMB119() China
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
AvaChem Scientific LLC USA
BOC Sciences
Biochempartner Co., Ltd China
Biogen Science & Technology Co., Ltd. China
CHEMSCENE, LLC 5mg/USD60();10mg/USD96() USA
Carbosynth Limited 10mg/USD55();25mg/USD95();50mg/USD150();100mg/USD210();250mg/USD375()
Cayman Chemical Company 500ug/USD97();1mg/USD184();5mg/USD776();10mg/USD1358() USA
Changsha Huakang Bio-Techology Development Co., Ltd. China
Hangzhou Skyherb Technologies Co., Ltd. China
J&K Scientific Ltd. 25mg/RMB393() China
Kinder Chemical Co., Limited China
MAYA-R 20mg/RMB168() China
Matrix Scientific 250mg/USD742();1g/USD1647() USA
MedChemexpress Co., Ltd. 5mg/USD60();10mg/USD96() USA
Nanning Weikang Pharmaceutical Technology Co., Ltd. China
Santa Cruz Biotechnology, Inc. 50mg/USD280() USA
Sanyuan Jinrui Bio-engineering Co., Ltd. China
Selleck Chemicals LLC 2mg/USD170(In stock);10mg/USD470(In stock);50mg/USD1270(In stock) USA
Shanghai DND Pharm-Technology Co., Inc. China
Shanghai Haoyuan Chemexpress Co., Ltd. 5mg/USD60();10mg/USD96() China
Shanghai Orient Chemical Co., Ltd. China
Shanghai Yingxuan Chempharm Co., Ltd. China
Shannxi Huike Botanical Development Co., Ltd. China
Sigma-Aldrich, Inc. 25mg/USD166() USA
Target Molecule Corp. 2mg/USD116();5mg/USD199();10mg/USD356();50mg/USD708() USA
Wuhan ChemFaces Biochemical Co., Ltd. 20mg/USD70() China
Xi'an App-Chem Bio (Tech) Co., Ltd. China
10

Related Products

Other Forms of 10338-51-9

Name CAS No Formula MW

Recommended Compounds in mTOR AMPK

Name CAS No Formula MW
SAR245409 934493-76-2 C13H14N6O 270.29
AP20187 195514-80-8 C82H107N5O20 1482.75
Nandrolone 434-22-0 C18H26O2 274.4
LY 303511 154447-38-8 C19H18N2O2 306.36
XL388 1251156-08-7 C23H22FN3O4S 455.5
Dihydromyricetin 27200-12-0 C15H12O8 320.25
nandrolone decanoate 360-70-3 C28H44O3 428.65
mTOR-IN-1 1207358-59-5 C25H30N8O2 474.56
ETP-46464 1345675-02-6 C30H22N4O2 470.52
AP1903 195514-63-7 C78H98N4O20 1411.63
QL-IX-55 1223002-54-7 C24H14F4N4O 450.39
WAY-600 1062159-35-6 C28H30N8O 494.59
WYE-687 1062161-90-3 C28H32N8O3 528.61
GDC-0349 1207360-89-1 C24H32N6O3 452.55
AZD2014 1009298-59-2 C25H30N6O3 462.54
PF-04691502 1013101-36-4 C22H27N5O4 425.48
BEZ235 (Tosylate) 1028385-32-1 C37H31N5O4S 641.74
GNE-477 1032754-81-6 C21H28N8O3S2 504.63
GNE-493 1033735-94-2 C17H20N6O2S 372.44
PI-103 (Hydrochloride) 371935-79-4 C19H17ClN4O3 384.82

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Salidroside

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