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465-99-6 (Hederagenin)



Hederagenin Hederagenin
Name Hederagenin
Formula C30H48O4
MW 472.7
CAS No. 465-99-6
EINECS 207-369-9
Smiles C[[email protected]@]1(CC[[email protected]](CC2)(C(O)=O)[[email protected]@]3([H])CC2(C)C)C3=CC[[email protected]@]4([H])[[email protected]@]1(C)CC[[email protected]]5([H])[[email protected]]4(C)CC[[email protected]](O)[[email protected]@]5(C)CO
Synonyms (3beta,4alpha)-3,23-Dihydroxyolean-12-en-28-oic acid; (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
InChI InChI=1S/C30H48O4/c1-25(2)13-15-30(24(33)34)16-14-28(5)19(20(30)17-25)7-8-22-26(3)11-10-23(32)27(4,18-31)21(26)9-12-29(22,28)6/h7,20-23,31-32H,8-18H2,1-6H3,(H,33,34)/t20-,21+,22+,23-,26-,27-,28+,29+,30-/m0/s1


Hederagenin is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo.

Background Information

Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells. ......by Affix Scientific
Hederagenin is a triterpenoid saponin isolated from the herbs of Hedera nepalensis, it exhibits the activity of antidepressant-like. Hederagenin can inhibit LPS-stimulated expression of iNOS, COX-2, and NF-κB. ......by BOC Sciences
Hederagenin, a triterpenoid saponin, is used to study the properties of triterpenoid saponins as biopesticides that prevent fungal growth, bacterial growth, and viral plant diseases. Hederagenin may be used as a reference in assays to detect it in biological fluids. Hederagenin Supplementation Alleviates the Pro-Inflammatory and Apoptotic Response to Alcohol in Rats. ......by MedKoo Biosciences, Inc.
Hederagenin is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. ......by Selleck Chemicals LLC
Extracted from HederanepalensisK.Kochvar.sinensis(Tobl.)Rehd.;Suitability:Hot water,hot methanol and ethanol;Store the product in sealed,cool and dry condition ......by Target Molecule Corp.

Protocol(Only for Reference)

Cell Experiment

Animal Experiment


Physical and Chemical Properties

Appearance: EBNumber:EB000014656

Storage condition

Up to one week at 4°C or six months at -20°C. by Affix Scientific


Soluble in DMSO by MedChemexpress Co., Ltd.

Mechanism and Indication

Signaling Pathways Others
Target Others
Research Area Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Hederagenin - No Development Reported

Safety Data of Hederagenin

Hazard Symbols : Xi
Risk Statements : 22
Safety Statements : 22-45

Spectral Information


Suppliers List

Company Price and Availability Country/Region
Affix Scientific 500mg/USD1600(In stock);1g/USD2150(In stock) USA
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 5mg/USD96();10mg/USD168() USA
Carbosynth Limited 5mg/USD70();10mg/USD130();25mg/USD288();50mg/USD525();100mg/USD900()
Extrasynthese Chemical S.A.S. France
MedChemexpress Co., Ltd. 5mg/USD96();10mg/USD168() USA
MedKoo Biosciences, Inc. USA
Nanjing Spring & Autumn Biological Engineering Co., Ltd. China
Santa Cruz Biotechnology, Inc. 250mg/USD860() USA
Selleck Chemicals LLC USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5mg/USD96();10mg/USD168() China
Sigma-Aldrich, Inc. 10mg/USD321() USA
Target Molecule Corp. 5mg/USD65();10mg/USD98();25mg/USD148();50mg/USD234() USA
Toronto Research Chemicals Inc. 5mg/USD75(Pending QC);10mg/USD140();25mg/USD310();50mg/USD575();100mg/USD995() Canada
Wuhan ChemFaces Biochemical Co., Ltd. 20mg/USD100() China

Related Products

Other Forms of 465-99-6

Name CAS No Formula MW
Hederagenin 28-D-glucoside 53931-25-2 C36H58O9 634.84

Recommended Compounds in Others

Name CAS No Formula MW
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 320.74
Dictamine 484-29-7 C12H9NO2 199.21
3,3',5-Triiodo-L-thyronine (sodium) 55-06-1 C15H11I3NNaO4 672.9553
Fabomotizole (hydrochloride) 173352-39-1 C15H22ClN3O2S 343.8721
FPH2 957485-64-2 C14H16ClN5O2S 353.83
α-Tocopherol (phosphate) 38976-17-9 C29H51O5P 510.69
BAMB-4 891025-25-5 C15H12N2O2 252.27
LDN-27219 312946-37-5 C20H16N4O2S2 408.5
ISO-1 478336-92-4 C12H13NO4 235.24
Aurothioglucose 12192-57-3 C6H11AuO5S 392.18
Oxybenzone 131-57-7 C14H12O3 228.24
ITX3 347323-96-0 C22H17N3OS 371.45
Cardiogreen 3599-32-4 C43H47N2NaO6S2 774.96
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 465.34
INH1 313553-47-8 C18H16N2OS 308.4
PF6-AM 1268491-69-5 C33H31BO12 630.4
XEN445 1515856-92-4 C18H17F3N2O3 366.33
Disperse Blue 148 52239-04-0 C19H19N5O4S 413.45026
Solvent Blue 35 17354-14-2 C22H26N2O2 350.454
CID-797718 370586-05-3 C12H11NO3 217.2206

Recommended Compounds in Same Indication

Name CAS No Formula MW

Route of Synthesis




More Information


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