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1449-05-4 (18α-Glycyrrhetinic acid)

1

Identification

18α-Glycyrrhetinic acid 18α-Glycyrrhetinic acid
Name 18α-Glycyrrhetinic acid
Formula C30H46O4
MW 470.68384
CAS No. 1449-05-4
EINECS 215-907-9
Smiles CC1(C)[[email protected]@H](O)CC[[email protected]@]2(C)[[email protected]@]1([H])CC[[email protected]]([[email protected]@](CC[[email protected]]3(C)[[email protected]]4([H])C[[email protected]@](C)(C(O)=O)CC3)(C)C4=C5)(C)[[email protected]]2([H])C5=O
Synonyms
InChI InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21+,22+,23-,26-,27+,28+,29-,30-/m1/s1
2

Introduction

18α-Glycyrrhetinic acid is an inhibitor of NF-kB and an activator of proteasome.

Background Information

The aglycone of glycyrrhizin ......by Affix Scientific
18α-Glycyrrhetinic acid is an inhibitor of NF-kB and an activator of proteasome. ......by MedChemexpress Co., Ltd.
Enoxolone (INN, BAN; also known as glycyrrhetinic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. It is used in flavoring and it masks the bitter taste of drugs like aloe and quinine. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000013516

Storage condition

Up to one week at 4°C or six months at -20°C. by Affix Scientific

Solubility

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Mechanism and Indication

Signaling Pathways
Target
Research Area
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
18α-Glycyrrhetinic acid - No Development Reported
7

Safety Data of 18α-Glycyrrhetinic acid

Hazard Symbols : Xn
Risk Statements : R22
Safety Statements : Section
RTECS : RK0190000
WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Affix Scientific 2g/USD395(In stock);4g/USD450(In stock) USA
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 100mg/USD60();500mg/USD168() USA
Extrasynthese Chemical S.A.S. France
MedChemexpress Co., Ltd. 100mg/USD60();500mg/USD168() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD60();500mg/USD168() China
Target Molecule Corp. 10mg/USD20();25mg/USD40();50mg/USD62();100mg/USD118() USA
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Related Products

Other Forms of 1449-05-4

Name CAS No Formula MW

Recommended Compounds in

Name CAS No Formula MW

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

12

References

Protocol Reference

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More Information

18α-Glycyrrhetinic acid

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