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65928-58-7 (Dienogest)

1

Identification

Dienogest Dienogest
Name Dienogest
Formula C20H25NO2
MW 311.42
CAS No. 65928-58-7
EINECS
Smiles C[[email protected]]([[email protected]@](CC#N)(O)CC1)(CC2)[[email protected]]1([H])[[email protected]@](CC3)([H])C2=C(CC4)C3=CC4=O
Synonyms 2-((8S,13S,14S,17R)-17-hydroxy-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)acetonitrile
InChI InChI=1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1
2

Introduction

Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.

Background Information

Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. ......by BOC Sciences
Dienogest is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis. ......by Selleck Chemicals LLC
Dienogest is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis. ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000013217

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 62 mg/mL (199.08 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) by Selleck Chemicals LLC
5

Mechanism and Indication

Signaling Pathways Autophagy Others
Target Progesterone Receptor Autophagy
Research Area Endocrinology
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Dienogest - Launched
7

Safety Data of Dienogest

8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Apichem Chemical Technology Co., Ltd. China
BOC Sciences
CHEMSCENE, LLC 10mg/USD96();50mg/USD346() USA
Jinan Chenghui-Shuangda Chemical Co., Ltd. China
MedChemexpress Co., Ltd. 10mg/USD96();50mg/USD346() USA
Selleck Chemicals LLC 10mg/USD120(In stock);10mM/1mLIn DMSO/USD160(In stock);25mg/USD270(In stock);100mg/USD770(In stock) USA
Shandong Chengchuang Pharmaceutical Technology Development Co., Ltd. China
Shanghai Everchem Co., Ltd. China
Shanghai Haoyuan Chemexpress Co., Ltd. 10mg/USD96();50mg/USD346() China
Target Molecule Corp. 10mg/USD120();50mg/USD190();100mg/USD339() USA
Zhejiang Xianju Xianle Pharmaceutical Co., Ltd. China
10

Related Products

Other Forms of 65928-58-7

Name CAS No Formula MW

Recommended Compounds in Progesterone Receptor Autophagy

Name CAS No Formula MW
Etonogestrel 54048-10-1 C22H28O2 324.46
Medroxyprogesterone 520-85-4 C22H32O3 344.49
Norethindrone 68-22-4 C20H26O2 298.42
Altrenogest 850-52-2 C21H26O2 310.43
Medroxyprogesterone (acetate) 71-58-9 C24H34O4 386.52
Dydrogesterone 152-62-5 C21H28O2 312.45
Levonorgestrel 797-63-7 C21H28O2 312.45
Drospirenone 67392-87-4 C24H30O3 366.49
Gestodene 60282-87-3 C21H26O2 310.43
Progesterone 57-83-0 C21H30O2 314.46
Tanaproget 304853-42-7 C16H15N3OS 297.37
Mifepristone 84371-65-3 C29H35NO2 429.59
Megestrol (Acetate) 595-33-5 C24H32O4 384.51
Ulipristal (acetate) 126784-99-4 C30H37NO4 475.62
Nestoron 7759-35-5 C23H30O4 370.48
19-Norethindrone acetate 51-98-9 C22H28O3 340.46
Hydroxyprogesterone 68-96-2 C21H30O3 330.46
Ethynodiol (diacetate) 297-76-7 C24H32O4 384.5085
Chlormadinone (acetate) 302-22-7 C23H29ClO4 404.927
Gestonorone Capronate 1253-28-7 C26H38O4 414.57752

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Dienogest

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