106685-40-9 (Adapalene)
1
Identification
Name |
Adapalene
|
Formula |
C28H28O3
|
MW |
412.52 |
CAS No. |
106685-40-9 |
EINECS |
|
Smiles |
O=C(C1=CC2=CC=C(C3=CC=C(OC)C(C45C[[email protected]@H](C[[email protected]](C6)C5)C[[email protected]@H]6C4)=C3)C=C2C=C1)O |
Synonyms |
CD 271;CD271;CD-271;Differin; 6-(3-((3r,5r,7r)-adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid |
InChI |
InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)/t17-,18+,19-,28? |
2
Introduction
Adapalene(CD-271; Differin), a synthetic retinoid, is a retinoic acid receptor agonist (RAR).
Target: Retinoic acid receptor agonist (RAR)
Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions.
Background Information
3
Protocol(Only for Reference)
Cell Experiment
Animal Experiment
4
Physical and Chemical Properties
Appearance:White to off-white Solid |
EBNumber:EB000013210 |
Storage condition
Solubility
5
Mechanism and Indication
6
Clinical Information
Product Name |
Sponsor & Collaborators |
Indications |
Start Date |
End Date |
Phase |
Adapalene
|
- |
|
|
|
Launched |
7
Safety Data of Adapalene
9
Suppliers List
Company |
Price and Availability |
Country/Region |
AOBIOUS INC |
1mg/USD11() |
USA |
AdooQ BioScience, LLC |
|
USA |
Ark Pharm, Inc. |
|
USA |
Asia Talent Chemical Limited |
|
China |
BOC Sciences |
|
|
Beijing Dezhong Wanquan Medicines Technological Development Co., Ltd. |
|
China |
Beijing FaMuRuiSi Pharmaceuticals Co., Ltd. |
|
China |
Beijing Mediking Biopharm Co., Ltd. |
|
China |
Beijing Mesochem Technology Co., Ltd. |
|
China |
Biochempartner Co., Ltd |
|
China |
Broad Pharmaceutical Co., Ltd. |
|
China |
CHEMSCENE, LLC |
50mg/USD60();100mg/USD96() |
USA |
Cayman Chemical Company |
|
USA |
Dyna International (Huaian) Co., Ltd |
|
CHINA |
Hangzhou Best Chemical Co., Ltd. |
|
China |
Hangzhou Hysen Pharma Co., Ltd. |
|
China |
Hubei Widely Chemical Technology Co., Ltd. |
|
China |
Huzhou Hengyuan Biochem. Tech. Co., Ltd. |
|
China |
Jiangsu Zhongdan Group Co., Ltd. |
|
China |
Jinan Chuancheng Pharmaceutical Co., Ltd. |
|
China |
MedChemexpress Co., Ltd. |
50mg/USD60();100mg/USD96() |
USA |
MedKoo Biosciences, Inc. |
|
USA |
Selleck Chemicals LLC |
25mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock);50mg/USD170(In stock) |
USA |
Shanghai Haoyuan Chemexpress Co., Ltd. |
50mg/USD60();100mg/USD96() |
China |
Shanghai RenYoung Pharmaceutical Co., Ltd. |
|
China |
Target Molecule Corp. |
2mg/USD20();10mg/USD56();25mg/USD108();50mg/USD198() |
USA |
Tocris Bioscience Inc. |
|
USA |
Wonder Synthesis (Beijing) Science and Development Co., Ltd. |
|
China |
10
Related Products
Other Forms of 106685-40-9
Recommended Compounds in
RAR/RXR
Recommended Compounds in Same Indication