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72-48-0 (Alizarin)

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Identification

Alizarin Alizarin
Name Alizarin
Formula C14H8O4
MW 240.21
CAS No. 72-48-0
EINECS 200-782-5
Smiles O=C(C1=C2C=CC=C1)C3=C(O)C(O)=CC=C3C2=O
Synonyms C.I. 58000; Mordant Red 11; 1,2-Dihydroxyanthraquinone; Alizarin Red; Dihydroxy-9,10-anthracenedione; 1,2-Dihydroxy-9,10-anthracenedione; 1,2-dihydroxyanthracene-9,10-dione
InChI InChI=1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H
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Introduction

Alizarin strongly inhibits P450 isoform CYP1A1, CYP1A2 and CYP1B1 with IC50 of 6.2 μM, 10.0 μM and 2.7 μM, respectively; weakly inhibits CYP2A6 and CYP2E1, and does not inhibit CYP2C19, CYP3A4 and CYP3A5.

Background Information

Alizarin is novelly used as a staining agent in biological research because it stains free calcium and certain calcium compounds a red or light purple color. ......by AdooQ BioScience, LLC
Alizarin strongly inhibits P450 isoform CYP1A1, CYP1A2 and CYP1B1 with IC50 of 6.2 μM, 10.0 μM and 2.7 μM, respectively; weakly inhibits CYP2A6 and CYP2E1, and does not inhibit CYP2C19, CYP3A4 and CYP3A5. ......by BOC Sciences
Alizarin strongly inhibits P450 isoform CYP1A1, CYP1A2 and CYP1B1 with IC50 of 6.2 μM, 10.0 μM and 2.7 μM, respectively; weakly inhibits CYP2A6 and CYP2E1, and does not inhibit CYP2C19, CYP3A4 and CYP3A5. ......by Selleck Chemicals LLC
Alizarin or 1,2-dihydroxyanthraquinoneis an organic compound that has been used throughout history as a prominent red dye, principally for dyeing textile fabrics. Historically it was derived from the roots of plants of the madder genus. In 1869, it became the first natural pigment to be duplicated synthetically. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000013169

Storage condition

Solubility

(25°C) * In vitro DMSO 48 mg/mL (199.82 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways
Target
Research Area
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Alizarin - No Development Reported
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Safety Data of Alizarin

Hazard Symbols : Xi
Risk Statements : 36/38-36/37/38
Safety Statements : S24/25
RTECS : YO8300000
WGKGermany : 3
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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
AdooQ BioScience, LLC USA
Aktin Chemicals Inc China
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
BOC Sciences
Cayman Chemical Company USA
Chem Service, Inc. USA
Chemos GmbH Germany
Chengdu Herbpurify Co., Ltd. China
Discovery Fine Chemicals Ltd.
Extrasynthese Chemical S.A.S. France
Quzhou MingFeng Chemical Co., Ltd. China
Selleck Chemicals LLC 25mg/USD120(In stock);10mM/1mLIn DMSO/USD160(In stock);100mg/USD370(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. China
Shanghai Tauto Biotech Co., Ltd. China
Target Molecule Corp. 20mg/USD30();50mg/USD55();200mg/USD165() USA
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Related Products

Other Forms of 72-48-0

Name CAS No Formula MW
Alizarin yellow R (sodium salt) 1718-34-9 C13H8N3NaO5 309.21
Alizarin yellow GG 584-42-9 C13H8N3NaO5 309.21

Recommended Compounds in

Name CAS No Formula MW

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

Protocol Reference

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More Information

Alizarin

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