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925701-88-8 (Acitretin (sodium))

1

Identification

Acitretin (sodium) Acitretin (sodium)
Name Acitretin (sodium)
Formula C21H25NaO3
MW 348.41
CAS No. 925701-88-8
EINECS
Smiles CC(/C=C/C(C(C)=CC(OC)=C1C)=C1C)=CC=CC(C)=CC(O[Na])=O
Synonyms Ro 10-1670 sodium;Soriatane sodium; sodium (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
InChI InChI=1S/C21H26O3.Na/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4;/h7-13H,1-6H3,(H,22,23);/q;+1/p-1/b9-7+,11-10+,14-8+,15-12+;
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Introduction

Acitretin sodium(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Target: RAR/RXR Acitretin sodium is a second-generation, systemic retinoid that has been approved for the treatment of psoriasis since 1997.

Background Information

Acitretin sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. It can be considered one of the treatments of choice for pustular and erythrodermic psoriasis. However, the efficacy of acitretin sodium as a mono ......by BOC Sciences
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000013133

Storage condition

Solubility

DMSO 20 mg/mL; Water <1 mg/mL by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Metabolic Enzyme/Protease
Target RAR/RXR
Research Area Inflammation/Immunology
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Acitretin (sodium) - Launched
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Safety Data of Acitretin (sodium)

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
Ark Pharm, Inc. USA
BOC Sciences
CHEMSCENE, LLC 100mg/USD154();200mg/USD252() USA
MedChemexpress Co., Ltd. 100mg/USD154();200mg/USD252() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD154();200mg/USD252() China
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Related Products

Other Forms of 925701-88-8

Name CAS No Formula MW
Acitretin 55079-83-9 C21H26O3 326.43

Recommended Compounds in RAR/RXR

Name CAS No Formula MW
AGN 205728 859498-05-8 C29H27NO3 437.53
AGN 196996 958295-17-5 C24H20BrNO5 482.32
AGN 194310 229961-45-9 C28H24O2S 424.55
Acitretin 55079-83-9 C21H26O3 326.43
Adapalene (sodium salt) 911110-93-5 C28H27NaO3 434.5
Adapalene 106685-40-9 C28H28O3 412.52
TTNPB 71441-28-6 C24H28O2 348.48
Magnolol 528-43-8 C18H18O2 266.33
Tazarotene 118292-40-3 C21H21NO2S 351.46
Fenretinide 65646-68-6 C26H33NO2 391.55
LG 100268 153559-76-3 C24H29NO2 363.49
Isotretinoin 4759-48-2 C20H28O2 300.44
Palovarotene 410528-02-8 C27H30N2O2 414.54
Retinoic acid 302-79-4 C20H28O2 300.44
AM580 102121-60-8 C22H25NO3 351.44
(R)-Flurbiprofen 51543-40-9 C15H13FO2 244.2609
Tamibarotene 94497-51-5 C22H25NO3 351.44
Bexarotene 153559-49-0 C24H28O2 348.48
AGN 195183 367273-07-2 C22H22ClF2NO4 437.86
AR7 80306-38-3 C15H12ClNO 0.0

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Acitretin (sodium)

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