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90038-01-0 (Detomidine (hydrochloride))

1

Identification

Detomidine (hydrochloride) Detomidine (hydrochloride)
Name Detomidine (hydrochloride)
Formula C12H15ClN2
MW 222.71
CAS No. 90038-01-0
EINECS
Smiles CC1=C(C)C(CC2=CN=CN2)=CC=C1.Cl
Synonyms 5-(2,3-dimethylbenzyl)-1H-imidazole hydrochloride
InChI InChI=1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H
2

Introduction

Detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist Target: α2-adrenergic agonist Detomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses.

Background Information

Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors. ......by Selleck Chemicals LLC
Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012953

Storage condition

Solubility

DMSO 45 mg/mL (202 mM); Water 45 mg/mL (202 mM) by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 45 mg/mL (202.05 mM); Water45 mg/mL (202.05 mM); Ethanol45 mg/mL (202.05 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways GPCR/G Protein
Target Adrenergic Receptor
Research Area Neurological Disease
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Detomidine (hydrochloride) - Launched
Detomidine (hydrochloride) - No Development Reported
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Safety Data of Detomidine (hydrochloride)

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
Anhui Lianchuang Pharmaceutical Chemistry Co., Ltd. China
Arpadis (China) Co., Ltd CHINA
BOC Sciences
Biochempartner Co., Ltd China
Brook Chemical Limited China
CHEMSCENE, LLC 10mg/USD60();50mg/USD96() USA
JACX Chemical Co., Ltd. China
MedChemexpress Co., Ltd. 10mg/USD60();50mg/USD96() USA
PharmaSci Shanghai Co., Ltd. China
Selleck Chemicals LLC 10mg/USD110(In stock);10mM/1mLIn DMSO/USD140(In stock);100mg/USD770(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 10mg/USD60();50mg/USD96() China
Target Molecule Corp. 10mg/USD73();100mg/USD301() USA
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Related Products

Other Forms of 90038-01-0

Name CAS No Formula MW
Detomidine 76631-46-4 C12H14N2 186.25

Recommended Compounds in Adrenergic Receptor

Name CAS No Formula MW
Tolazoline 59-98-3 C10H12N2 160.22
Synephrine (hydrochloride) 5985-28-4 C9H14ClNO2 203.67
(R)-(-)-Phenylephrine 59-42-7 C9H13NO2 167.205
Nicergoline 27848-84-6 C24H26BrN3O3 484.39
Tamsulosin (hydrochloride) 106463-17-6 C20H29ClN2O5S 444.97
Tamsulosin 106133-20-4 C20H28N2O5S 408.51
UK 14,304 59803-98-4 C11H10BrN5 292.13
Guanfacine 29110-47-2 C9H9Cl2N3O 246.09
Propranolol (hydrochloride) 318-98-9 C16H22ClNO2 295.8
Guanabenz (Acetate) 23256-50-0 C10H12Cl2N4O2 291.13
Tetrahydrozoline (hydrochloride) 522-48-5 C13H17ClN2 236.74
Octopamine (hydrochloride) 770-05-8 C8H12ClNO2 189.64
Betaxolol (hydrochloride) 63659-19-8 C18H30ClNO3 343.89
Indacaterol (maleate) 753498-25-8 C28H32N2O7 508.56
Medetomidine (hydrochloride) 86347-15-1 C13H17ClN2 236.74
Norepinephrine (bitartrate monohydrate) 108341-18-0 C12H19NO10 337.28
Norepinephrine (hydrochloride) 329-56-6 C8H12ClNO3 205.64
Xylometazoline (hydrochloride) 1218-35-5 C16H25ClN2 280.84
(R)-(-)-Phenylephrine (hydrochloride) 61-76-7 C9H14ClNO2 203.67
Isoprenaline (hydrochloride) 51-30-9 C11H18ClNO3 247.72

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Detomidine (hydrochloride)

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