• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

50-81-7 (L-Ascorbic acid)

1

Identification

L-Ascorbic acid L-Ascorbic acid
Name L-Ascorbic acid
Formula C6H8O6
MW 176.12
CAS No. 50-81-7
EINECS 200-066-2
Smiles OC([[email protected]@H]([[email protected]@H](O)CO)OC1=O)=C1O
Synonyms L-Ascorbic acid; Vitamin C; L-Threo-2,3,4,5,6-pentahydroxy-1-hexenoic acid-4-lactone; (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one
InChI InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
2

Introduction

Ascorbic acid is a naturally occurring organic compound with antioxidant properties. Target: Others Ascorbic acid is a naturally occurring organic compound with antioxidant properties.

Background Information

Ascorbic acid is a naturally occurring organic compound with antioxidant properties. ......by BOC Sciences
Also known as Vitamin C, Ascorbic acid functions as a powerful antioxidant, particularly in regards to reactive oxygen species (ROS). It functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Also enhances iPSC generation from both mouse and human somatic cells. ......by BioVision, Inc.,
Vitamin C or L-ascorbic acid, or simply ascorbate (the anion of ascorbic acid), is an essential nutrient for humans and certain other animal species. ......by MedKoo Biosciences, Inc.
Vitamin C is a water-soluble vitamin indicated for the prevention and treatment of scurvy. ......by Selleck Chemicals LLC
Vitamin C is a water-soluble vitamin indicated for the prevention and treatment of scurvy. ......by Target Molecule Corp.
Inhibitor of Cav3.2 channels (IC50 = 6.5 μM); displays no effect on Cav3.1 or Cav3.3 channels heterologously expressed in HEK 293 cells. Also enhances the generation of induced pluripotent stem cells (iPSCs) from mouse and human somatic cells by increasing reprogramming efficiency. Naturally occurring antioxidant. ......by Tocris Bioscience Inc.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012947

Storage condition

Store at RT by Tocris Bioscience Inc.

Solubility

DMSO by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 35 mg/mL (198.72 mM); Water35 mg/mL (198.72 mM); Ethanol<1 mg/mL (<1 mM) by Selleck Chemicals LLC
Soluble to 500 mM in water and to 100 mM in DMSO by Tocris Bioscience Inc.
5

Mechanism and Indication

Signaling Pathways Others
Target Others
Research Area Metabolic Disease
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
L-Ascorbic acid - Launched
7

Safety Data of L-Ascorbic acid

Hazard Symbols : Xn
Risk Statements : 20/21/22-36/37/38
Safety Statements : S24/25
HS Code : 29362700
RTECS : CI7650000
WGKGermany : 1
8

Spectral Information

9

Suppliers List

10

Related Products

Other Forms of 50-81-7

Name CAS No Formula MW
L-Ascorbic acid sodium salt 134-03-2 C6H7NaO6 198.11
L-Ascorbic acid (calcium) 5743-27-1 C6H8O6 176.12
Calcium ascorbate dihydrate 5743-28-2 C12H18CaO14 426.34

Recommended Compounds in Others

Name CAS No Formula MW
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 320.74
Dictamine 484-29-7 C12H9NO2 199.21
3,3',5-Triiodo-L-thyronine (sodium) 55-06-1 C15H11I3NNaO4 672.9553
Fabomotizole (hydrochloride) 173352-39-1 C15H22ClN3O2S 343.8721
FPH2 957485-64-2 C14H16ClN5O2S 353.83
α-Tocopherol (phosphate) 38976-17-9 C29H51O5P 510.69
BAMB-4 891025-25-5 C15H12N2O2 252.27
LDN-27219 312946-37-5 C20H16N4O2S2 408.5
ISO-1 478336-92-4 C12H13NO4 235.24
Aurothioglucose 12192-57-3 C6H11AuO5S 392.18
Oxybenzone 131-57-7 C14H12O3 228.24
ITX3 347323-96-0 C22H17N3OS 371.45
Cardiogreen 3599-32-4 C43H47N2NaO6S2 774.96
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 465.34
INH1 313553-47-8 C18H16N2OS 308.4
PF6-AM 1268491-69-5 C33H31BO12 630.4
XEN445 1515856-92-4 C18H17F3N2O3 366.33
Disperse Blue 148 52239-04-0 C19H19N5O4S 413.45026
Solvent Blue 35 17354-14-2 C22H26N2O2 350.454
CID-797718 370586-05-3 C12H11NO3 217.2206

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

[1]. Lachapelle MY, et al. Inactivation dates of the human and guinea pig vitamin C genes. Genetica. 2011 Feb;139(2):199-207.

Protocol Reference

Padayatty et al (2003) Vitamin C as an antioxidant: evaluation of its role in disease prevention. J.Am.Coll.Nutr. 22 18. PMID: 12569111.

Nelson et al (2007) Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J.Neurosci. 27 12577. PMID: 18003836.

Esteban et al (2010) Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 6 71. PMID: 20036631.

......by Tocris Bioscience Inc.
13

More Information

L-Ascorbic acid

Tags: buy 50-81-7 IC50 | 50-81-7 price | 50-81-7 cost | 50-81-7 solubility | 50-81-7 purchase | 50-81-7 manufacturer | 50-81-7 research buy | 50-81-7 order | 50-81-7 MSDS | 50-81-7 chemical structure | 50-81-7 Storage condition | 50-81-7 molecular weight | 50-81-7 mw | 50-81-7 datasheet | 50-81-7 supplier | 50-81-7 cell line | 50-81-7 NMR | 50-81-7 MS | 50-81-7 IR | 50-81-7 solubility | 50-81-7 Safe information | 50-81-7 Qc and Spectral Information | 50-81-7 Clinical Information | 50-81-7 Clinical Trial | 50-81-7 Route of Synthesis | 50-81-7 storage condition | 50-81-7 diseases and conditions | 50-81-7 flash point | 50-81-7 boiling point | 50-81-7 melting point | 50-81-7 storage condition | 50-81-7 brand