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15291-75-5 (Ginkgolide A)

1

Identification

Ginkgolide A Ginkgolide A
Name Ginkgolide A
Formula C20H24O9
MW 408.4
CAS No. 15291-75-5
EINECS
Smiles O=C1[[email protected]@H](C)[[email protected]]2(O)[[email protected]@]3(C4=O)C(C5([[email protected]@H](O)C(O6)=O)C6O3)([[email protected]](O4)C[[email protected]]5C(C)(C)C)C[[email protected]]2([H])O1
Synonyms BN52020
InChI InChI=1S/C20H24O9/c1-7-12(22)26-10-6-17-9-5-8(16(2,3)4)18(17)11(21)13(23)28-15(18)29-20(17,14(24)27-9)19(7,10)25/h7-11,15,21,25H,5-6H2,1-4H3/t7-,8+,9-,10+,11+,15?,17?,18?,19-,20-/m1/s1
2

Introduction

Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist. Target: GABA Receptor Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree.

Background Information

Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. ......by Affix Scientific
Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM. ......by BOC Sciences
Ginkgolide A is GSK-3β inhibitor and potential PXR agonist found in Ginkgo. It decreases phosphorylation of Tau protein, prevents neointimal hyperplasia and decreases anxiety. ......by MedKoo Biosciences, Inc.
Extracted from Ginkgo biloba L.;Suitability:Ethyl acetate,methanol,ethanol,two sulfoxide;Store the product in sealed,cool and dry condition ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012507

Storage condition

Up to one week at 4°C or six months at -20°C. by Affix Scientific

Solubility

DMSO 80 mg/mL; Water <1 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 81 mg/mL (198.33 mM); Ethanol2 mg/mL (4.89 mM); Water<1 mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Ginkgolide A - Launched
Ginkgolide A - No Development Reported
7

Safety Data of Ginkgolide A

WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AOBIOUS INC USA
AdooQ BioScience, LLC USA
Affix Scientific 1g/USD1(In stock);500mg/USD850(In stock) USA
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
AvaChem Scientific LLC USA
BOC Sciences 20mg/USD198(In stock)
Biochempartner Co., Ltd China
CHEMSCENE, LLC 10mg/USD60();50mg/USD210() USA
Cayman Chemical Company USA
Chengdu Cogon Bio-tech Co., Ltd. China
MedChemexpress Co., Ltd. 10mg/USD60();50mg/USD210() USA
MedKoo Biosciences, Inc. USA
Nanjing Tcm Institute of Chinese Materia Medica China
Selleck Chemicals LLC 25mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 10mg/USD60();50mg/USD210() China
Target Molecule Corp. 10mg/USD74();20mg/USD125();50mg/USD210() USA
10

Related Products

Other Forms of 15291-75-5

Name CAS No Formula MW

Recommended Compounds in GABA Receptor

Name CAS No Formula MW
Tiagabine (hydrochloride) 145821-59-6 C20H26ClNO2S2 412.01
alpha-Asarone 2883-98-9 C12H16O3 208.2536
Zopiclone 43200-80-2 C17H17ClN6O3 388.81
Tiagabine (hydrochloride) 145821-59-6 C20H26ClNO2S2 412.0089
Procaine (hydrochloride) 51-05-8 C13H21ClN2O2 272.77
Procaine 59-46-1 C13H20N2O2 236.31
Nefiracetam 77191-36-7 C14H18N2O2 246.3
Primidone 125-33-7 C12H14N2O2 218.25
(R)-Baclofen (hydrochloride) 63701-55-3 C10H13Cl2NO2 250.12
Etomidate (hydrochloride) 53188-20-8 C14H17ClN2O2 280.75
Etomidate 33125-97-2 C14H16N2O2 244.29
(+)-Bicuculline 485-49-4 C20H17NO6 367.35
Zolpidem 82626-48-0 C19H21N3O 307.39
Etifoxine 21715-46-8 C17H17ClN2O 300.78
Etifoxine (hydrochloride) 56776-32-0 C17H18Cl2N2O 337.24
Clobazam 22316-47-8 C16H13ClN2O2 300.74
(R)-Baclofen 69308-37-8 C10H12ClNO2 213.66
Vigabatrin (Hydrochloride) 1391054-02-6 C6H12ClNO2 165.62
Vigabatrin 68506-86-5 C6H11NO2 129.16
Acamprosate (calcium) 77337-73-6 C10H20CaN2O8S2 400.48

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

12

References

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More Information

Ginkgolide A

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