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29342-05-0 (Ciclopirox)

1

Identification

Ciclopirox Ciclopirox
Name Ciclopirox
Formula C12H17NO2
MW 207.27
CAS No. 29342-05-0
EINECS 249-577-2
Smiles CC(C=C(C1CCCCC1)N2O)=CC2=O
Synonyms Penlac;Batrafen;Loprox;Mycoster;Stieprox;HOE296b; 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
InChI InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3
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Introduction

Ciclopirox (Penlac) is a synthetic antifungal agent. Target: Antifungal Ciclopirox is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.

Background Information

Ciclopirox olamine (used in preparations called Batrafen, Loprox, Rejuvenail, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor. ......by BOC Sciences
Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator. ......by Selleck Chemicals LLC
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012179

Storage condition

Solubility

DMSO 42 mg/mL; Water <1 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 42 mg/mL (202.63 mM); Ethanol42 mg/mL (202.63 mM); Water<1 mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways Autophagy Anti-infection
Target Fungal Autophagy
Research Area Infection
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Ciclopirox - Launched
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Safety Data of Ciclopirox

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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
BOC Sciences
CHEMSCENE, LLC 50mg/USD120();100mg/USD180() USA
Liye Chemical Products Technology Development Co., Ltd. China
MedChemexpress Co., Ltd. 50mg/USD120();100mg/USD180() USA
Selleck Chemicals LLC 25mg/USD120(In stock);10mM/1mLIn DMSO/USD160(In stock);200mg/USD470(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 50mg/USD120();100mg/USD180() China
Target Molecule Corp. 5mg/USD41();25mg/USD114();100mg/USD228();200mg/USD357() USA
Zhejiang Huadee Dyestuff Chemical Co., Ltd. China
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Related Products

Other Forms of 29342-05-0

Name CAS No Formula MW
Ciclopirox ethanolamine 41621-49-2 0.0

Recommended Compounds in Fungal Autophagy

Name CAS No Formula MW
Micafungin 235114-32-6 C56H71N9O23S 1270.27
Pneumocandin B0 135575-42-7 C50H80N8O17 1065.21
UM729 1448723-60-1 C20H25N5O2 367.44
Sertaconazole (nitrate) 99592-39-9 C20H16Cl3N3O4S 500.78
Miconazole (nitrate) 22832-87-7 C18H15Cl4N3O4 479.14
Naftifine (hydrochloride) 65473-14-5 C21H22ClN 323.86
Hygromycin B 31282-04-9 C20H37N3O13 527.52
Miconazole 22916-47-8 C18H14Cl4N2O 416.13
Econazole (nitrate) 24169-02-6 C18H16Cl3N3O4 444.7
Methasulfocarb 66952-49-6 C9H11NO4S2 261.32
Flumorph 211867-47-9 C21H22FNO4 371.4
Itraconazole 84625-61-6 C35H38Cl2N8O4 705.63
Tolnaftate 2398-96-1 C19H17NOS 307.41
Fenticonazole (Nitrate) 73151-29-8 C24H21Cl2N3O4S 518.41
Liranaftate 88678-31-3 C18H20N2O2S 328.43
Tioconazole 65899-73-2 C16H13Cl3N2OS 387.71
Bifonazole 60628-96-8 C22H18N2 310.39
Butoconazole (nitrate) 64872-77-1 C19H18Cl3N3O3S 474.79
Amphotericin B 1397-89-3 C47H73NO17 924.08
Amorolfine (hydrochloride) 78613-38-4 C21H36ClNO 353.97

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Ciclopirox

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