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24169-02-6 (Econazole (nitrate))

1

Identification

Econazole (nitrate) Econazole (nitrate)
Name Econazole (nitrate)
Formula C18H16Cl3N3O4
MW 444.7
CAS No. 24169-02-6
EINECS 246-053-5
Smiles [O-][N+](O)=O.ClC1=C(C=CC(Cl)=C1)C(OCC2=CC=C(Cl)C=C2)CN3C=CN=C3
Synonyms Spectazole;Ecostatin;Pevaryl;Palavale; 1-(2-((4-chlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate
InChI InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
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Introduction

Econazole nitrate (Spectazole) is an imidazole class antifungal medication. Target: Antifungal Econazole nitrate is an antifungal medication of the imidazole class.

Background Information

Econazole nitrate (Spectazole) is an imidazole class antifungal medication.It is used as a cream under the brand names Spectazole (United States), Ecostatin (Canada), Pevaryl (Western Europe), and Pevisone (the latter consisting of the combination econazo ......by BOC Sciences
Econazole Nitrate is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus. ......by Selleck Chemicals LLC
A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012172

Storage condition

Solubility

DMSO 90 mg/mL; Water <1 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 89 mg/mL (200.13 mM); Ethanol5 mg/mL (11.24 mM); Water<1 mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways Anti-infection
Target Fungal
Research Area Infection
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Econazole (nitrate) - Launched
7

Safety Data of Econazole (nitrate)

Hazard Symbols : Xn,Xi
Risk Statements : 22-36/38-36/37/38
Safety Statements : 26-36-36/37
RTECS : NI4450000
WGKGermany : 3
8

Spectral Information

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Suppliers List

Company Price and Availability Country/Region
BOC Sciences
CHEMSCENE, LLC 1g/USD60();5g/USD96() USA
Jintan Chengxi Xinda Chemical Co. Ltd. China
Jurong Renxin Chemical Co., Ltd. China
MedChemexpress Co., Ltd. 1g/USD60();5g/USD96() USA
Selleck Chemicals LLC 50mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) USA
Shaanxi Dasheng Chemical Tech Co., Ltd. China
Shanghai Haoyuan Chemexpress Co., Ltd. 1g/USD60();5g/USD96() China
Target Molecule Corp. 1mg/USD20();5mg/USD40();10mg/USD67();50mg/USD198() USA
Yung Zip Chemical Co., Ltd. Taiwan, China
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Related Products

Other Forms of 24169-02-6

Name CAS No Formula MW
Econazole 27220-47-9 C18H15Cl3N2O 381.68

Recommended Compounds in Fungal

Name CAS No Formula MW
Micafungin 235114-32-6 C56H71N9O23S 1270.27
Pneumocandin B0 135575-42-7 C50H80N8O17 1065.21
UM729 1448723-60-1 C20H25N5O2 367.44
Sertaconazole (nitrate) 99592-39-9 C20H16Cl3N3O4S 500.78
Miconazole (nitrate) 22832-87-7 C18H15Cl4N3O4 479.14
Naftifine (hydrochloride) 65473-14-5 C21H22ClN 323.86
Hygromycin B 31282-04-9 C20H37N3O13 527.52
Miconazole 22916-47-8 C18H14Cl4N2O 416.13
Ciclopirox 29342-05-0 C12H17NO2 207.27
Methasulfocarb 66952-49-6 C9H11NO4S2 261.32
Flumorph 211867-47-9 C21H22FNO4 371.4
Itraconazole 84625-61-6 C35H38Cl2N8O4 705.63
Tolnaftate 2398-96-1 C19H17NOS 307.41
Fenticonazole (Nitrate) 73151-29-8 C24H21Cl2N3O4S 518.41
Liranaftate 88678-31-3 C18H20N2O2S 328.43
Tioconazole 65899-73-2 C16H13Cl3N2OS 387.71
Bifonazole 60628-96-8 C22H18N2 310.39
Butoconazole (nitrate) 64872-77-1 C19H18Cl3N3O3S 474.79
Amphotericin B 1397-89-3 C47H73NO17 924.08
Amorolfine (hydrochloride) 78613-38-4 C21H36ClNO 353.97

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Econazole (nitrate)

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