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71-58-9 (Medroxyprogesterone (acetate))

1

Identification

Medroxyprogesterone (acetate) Medroxyprogesterone (acetate)
Name Medroxyprogesterone (acetate)
Formula C24H34O4
MW 386.52
CAS No. 71-58-9
EINECS 200-757-9
Smiles O=C1CC(COC(C)=O)[[email protected]]2(C)[[email protected]@]3([H])CC[[email protected]]4(C)[[email protected]@H](C(C)=O)CC[[email protected]@]4([H])[[email protected]]3([H])CCC2=C1
Synonyms Hydroxymethylprogesterone acetate; 17alpha-Acetoxy-6-alpha-methylpregn-4-ene-3,20-dione; 17a-Hydroxy-6a-methyl-4-pregnene-3,20-dione acetate; Depo-provera; ((8S,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl)methyl acetate
InChI InChI=1S/C24H34O4/c1-14(25)20-7-8-21-19-6-5-16-11-18(27)12-17(13-28-15(2)26)24(16,4)22(19)9-10-23(20,21)3/h11,17,19-22H,5-10,12-13H2,1-4H3/t17?,19-,20+,21-,22-,23+,24+/m0/s1
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Introduction

Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist. Target: Progesterone Receptor Medroxyprogesterone acetate(MPA) is a steroidal progestin, a synthetic variant of the human hormone progesterone.

Background Information

Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist. ......by BOC Sciences
Medroxyprogesterone acetate (MPA) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding. ......by Selleck Chemicals LLC
A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000012156

Storage condition

Solubility

DMSO 12 mg/mL; Water <1 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 12 mg/mL (31.04 mM); Ethanol12 mg/mL warming (31.04 mM); Water<1 mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways Others
Target Progesterone Receptor
Research Area Endocrinology
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Medroxyprogesterone (acetate) - Launched
Medroxyprogesterone (acetate) - Phase 4
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Safety Data of Medroxyprogesterone (acetate)

Hazard Symbols : Xn
Risk Statements : R40;R48
Safety Statements : S22;S36/37/39;S45
RTECS : TU5010000
WGKGermany : 3
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Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 100mg/USD60();500mg/USD72() USA
Hunan Steroid Chemicals Co., Ltd. China
Jiangxi Hongyuan Pharmaceutical Raw Material Co., Ltd. China
LKT Laboratories Inc. USA
MedChemexpress Co., Ltd. 100mg/USD60();500mg/USD72() USA
Melone Pharmaceutical Co., Ltd. China
Selleck Chemicals LLC 50mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD60();500mg/USD72() China
Taizhou Baida Pharmaceutical Co., Ltd. China
Target Molecule Corp. 2mg/USD20();10mg/USD65();50mg/USD136() USA
Xi'an Gaoyuan Bio-Chem Co., Ltd. China
Xi'an Jiangxing Biotechnique Co., Ltd. China
Zhejiang Horde Pharma Co., Ltd CHINA
Zhejiang Xianju Xianle Pharmaceutical Co., Ltd. China
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Related Products

Other Forms of 71-58-9

Name CAS No Formula MW
Medroxyprogesterone 520-85-4 C22H32O3 344.49

Recommended Compounds in Progesterone Receptor

Name CAS No Formula MW
Etonogestrel 54048-10-1 C22H28O2 324.46
Medroxyprogesterone 520-85-4 C22H32O3 344.49
Norethindrone 68-22-4 C20H26O2 298.42
Altrenogest 850-52-2 C21H26O2 310.43
Dydrogesterone 152-62-5 C21H28O2 312.45
Levonorgestrel 797-63-7 C21H28O2 312.45
Drospirenone 67392-87-4 C24H30O3 366.49
Gestodene 60282-87-3 C21H26O2 310.43
Dienogest 65928-58-7 C20H25NO2 311.42
Progesterone 57-83-0 C21H30O2 314.46
Tanaproget 304853-42-7 C16H15N3OS 297.37
Mifepristone 84371-65-3 C29H35NO2 429.59
Megestrol (Acetate) 595-33-5 C24H32O4 384.51
Ulipristal (acetate) 126784-99-4 C30H37NO4 475.62
Nestoron 7759-35-5 C23H30O4 370.48
19-Norethindrone acetate 51-98-9 C22H28O3 340.46
Hydroxyprogesterone 68-96-2 C21H30O3 330.46
Ethynodiol (diacetate) 297-76-7 C24H32O4 384.5085
Chlormadinone (acetate) 302-22-7 C23H29ClO4 404.927
Gestonorone Capronate 1253-28-7 C26H38O4 414.57752

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

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More Information

Medroxyprogesterone (acetate)

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