62-44-2 (Phenacetin)
1
Identification
| Name |
Phenacetin
|
| Formula |
C10H13NO2
|
| MW |
179.22 |
| CAS No. |
62-44-2 |
| EINECS |
200-533-0 |
| Smiles |
CC(NC1=CC=C(OCC)C=C1)=O |
| Synonyms |
4'-Ethoxyacetanilide; 4-Acetophenetidine; N-(4-ethoxyphenyl)acetamide |
| InChI |
InChI=1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12) |
2
Introduction
Phenacetin is a non-opioid analgesic without anti-inflammatory properties.
Target: COX
Phenacetin is a pain-relieving and fever-reducing drug, Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy.
Background Information
3
Protocol(Only for Reference)
Cell Experiment
Animal Experiment
4
Physical and Chemical Properties
| Appearance:White to off-white Solid |
EBNumber:EB000012148 |
Storage condition
Solubility
5
Mechanism and Indication
6
Clinical Information
| Product Name |
Sponsor & Collaborators |
Indications |
Start Date |
End Date |
Phase |
|
Phenacetin
|
- |
|
|
|
Launched |
|
Phenacetin
|
- |
|
|
|
No Development Reported |
7
Safety Data of Phenacetin
9
Suppliers List
| Company |
Price and Availability |
Country/Region |
| AA Blocks LLC |
|
|
| AbMole BioScience |
|
USA |
| AdooQ BioScience, LLC |
|
USA |
| Alfa Chemistry |
|
USA |
| Apexbio Technology LLC |
|
USA |
| Ark Pharm, Inc. |
|
USA |
| BLD Pharmatech |
|
|
| Biochempartner Co., Ltd |
|
China |
| CHEMSCENE, LLC |
1g/USD60();5g/USD96() |
USA |
| Cayman Chemical Company |
|
USA |
| Changzhou Sunchem Pharmaceutical Chemical Material Co., Ltd. |
|
China |
| Chem Service, Inc. |
|
USA |
| Crescent Chemical Co. Inc. |
|
USA |
| Hubie Xinyuanshun Pharm&Chem Co., Ltd. |
|
China |
| MedChemexpress Co., Ltd. |
1g/USD60();5g/USD96() |
USA |
| MedKoo Biosciences, Inc. |
|
USA |
| Selleck Chemicals LLC |
50mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) |
USA |
| Shanghai Everchem Co., Ltd. |
|
China |
| Shanghai Haoyuan Chemexpress Co., Ltd. |
1g/USD60();5g/USD96() |
China |
| Target Molecule Corp. |
2mg/USD20();10mg/USD42();50mg/USD98();200mg/USD122() |
USA |
10
Related Products
Other Forms of 62-44-2
Recommended Compounds in
COX
Recommended Compounds in Same Indication
12
References
[1]. Tan, G.H., M.D. Rabbino, and J. Hopper, Jr., Is Phenacetin a Nephrotoxin?A Report on Twenty-Three Users of the Drug. Calif Med, 1964. 101: p. 73-7.
[2]. Brix, A.E., Renal papillary necrosis. Toxicol Pathol, 2002. 30(6): p. 672-4.
[3]. Dubach, U.C., B. Rosner, and T. Sturmer, An epidemiologic study of abuse of analgesic drugs. Effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987). N Engl J Med, 1991. 324(3): p. 155-60.
Protocol Reference
