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61-68-7 (Mefenamic acid)

1

Identification

Mefenamic acid Mefenamic acid
Name Mefenamic acid
Formula C15H15NO2
MW 241.29
CAS No. 61-68-7
EINECS 200-513-1
Smiles OC(C1=C(C=CC=C1)NC2=C(C)C(C)=CC=C2)=O
Synonyms 2-[(2,3-Dimethylphenyl)amino]benzoic acid; N-(2,3-Xylyl)anthranilic acid; 2-((2,3-dimethylphenyl)amino)benzoic acid
InChI InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
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Introduction

Mefenamic acid is a non-steroidal anti-inflammatory agent, which is an inhibitor of cyclooxygenase. Target: COX Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain.

Background Information

Mefenamic Acid is a competitive inhibitor of COX-1 and COX-2. ......by AbMole BioScience
A competitive inhibitor of COX-1 and COX-2 ......by BOC Sciences
Mefenamic Acid is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase and has demonstrated antiproliferative activity against colorectal cancer cells. ......by MedKoo Biosciences, Inc.
Mefenamic acid is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of mefenamic acid is as a Cyclooxygenase Inhibitor. The chemical classification of mefenamic acid is Nonsteroidal Anti-inflammatory Compounds. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000011912

Storage condition

Solubility

DMSO 48 mg/mL; Water <1 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 48 mg/mL (198.93 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways Immunology/Inflammation
Target COX
Research Area Inflammation/Immunology
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Mefenamic acid - Launched
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Safety Data of Mefenamic acid

Hazard Symbols : Xn
Risk Statements : R22
Safety Statements : 22-36
RTECS : CB4550000
WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AA Blocks LLC
AbMole BioScience USA
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
BLD Pharmatech
BOC Sciences USA
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 5g/USD96();10g/USD180() USA
Cayman Chemical Company USA
Hangzhou Deli Chemical Co., Ltd. China
MedChemexpress Co., Ltd. 5g/USD96();10g/USD180() USA
MedKoo Biosciences, Inc. USA
Ningbo Medicn Pharmaceutical Co., Ltd. China
Pure Chemistry Scientific Inc. 100g/USD369(In stock) USA
Selleck Chemicals LLC 50mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5g/USD96();10g/USD180() China
Target Molecule Corp. 2mg/USD20();10mg/USD41();50mg/USD98();200mg/USD122() USA
Wisdom Pharmaceutical Co., Ltd. China
Yung Zip Chemical Co., Ltd. Taiwan, China
Zhejiang Qiming Pharmaceutical Co., Ltd. China
Zhejiang Tianxin Pharmaceutical Co., Ltd. China
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Related Products

Other Forms of 61-68-7

Name CAS No Formula MW

Recommended Compounds in COX

Name CAS No Formula MW
Isoorientin 4261-42-1 C21H20O11 448.3769
Maslinic acid 4373-41-5 C30H48O4 472.7
Aceclofenac 89796-99-6 C16H13Cl2NO4 354.18
Zaltoprofen 74711-43-6 C17H14O3S 298.36
Ketorolac 74103-06-3 C15H13NO3 255.27
Loxoprofen 68767-14-6 C15H18O3 246.3
Nabumetone 42924-53-8 C15H16O2 228.29
Triflusal 322-79-2 C10H7F3O4 248.16
Diclofenac (diethylamine) 78213-16-8 C18H22Cl2N2O2 369.29
Bufexamac 2438-72-4 C12H17NO3 223.27
Acemetacin 53164-05-9 C21H18ClNO6 415.82
Phenacetin 62-44-2 C10H13NO2 179.22
Tenoxicam 59804-37-4 C13H11N3O4S2 337.37
Flunixin (meglumine) 42461-84-7 0.0
Lornoxicam 70374-39-9 C13H10ClN3O4S2 371.82
Nimesulide 51803-78-2 C13H12N2O5S 308.31
Tolfenamic Acid 13710-19-5 C14H12ClNO2 261.7
Fenoprofen (Calcium) 34597-40-5 C30H26CaO6 522.6
Deracoxib 169590-41-4 C17H14F3N3O3S 397.37
Meloxicam 71125-38-7 C14H13N3O4S2 351.4

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

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More Information

Mefenamic acid

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