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123171-59-5 (Cefepime (Dihydrochloride Monohydrate))

1

Identification

Cefepime (Dihydrochloride Monohydrate) Cefepime (Dihydrochloride Monohydrate)
Name Cefepime (Dihydrochloride Monohydrate)
Formula C19H28Cl2N6O6S2
MW 571.5
CAS No. 123171-59-5
EINECS
Smiles O=C1N(C(C([O-])=O)=C2C[N+]3(C)CCCC3)[[email protected]@](SC2)([H])[[email protected]@H]1NC(/C(C4=CSC(N)=N4)=NOC)=O.O.Cl.Cl
Synonyms (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-[1-(1-methylpyrrolidinyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid hydrochloride monohydrate; (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((1-methylpyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride hydrate
InChI InChI=1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1
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Introduction

Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria. Target: Antibacterial Cefepime is an extended-spectrum parenteral cephalosporin antibiotic active in vitro against a broad spectrum of gram-positive and gram-negative aerobic bacteria.

Background Information

A fourth generation cephalosporin antibiotic ......by BOC Sciences
Cefepime dihydrochloride is a biochemical. ......by MedKoo Biosciences, Inc.
Cefepime Hydrochloride is a broad-spectrum cephalosporin with activity against Gram-positive and Gram-negative bacteria. It binds to penicillin-binding proteins and disrupts the cell wall synthesis. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases. (Last Updated: 02/10/2016). ......by MedKoo Biosciences, Inc.
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both Gram-negative and Gram-positive organisms than third-generation agents. Cefepime is usually reserved to treat severe nosocomial pneumonia, infections caused by multi-resistant microorganisms (e.g. Pseudomonas aeruginosa) and empirical treatment of febrile neutropenia. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000011844

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Anti-infection
Target Bacterial
Research Area Infection
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Cefepime (Dihydrochloride Monohydrate) - Launched
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Safety Data of Cefepime (Dihydrochloride Monohydrate)

Hazard Symbols : Xi
Risk Statements : 36/37/38-42/43
Safety Statements : 22-26-36/37/39
HS Code : 29419000
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Spectral Information

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Suppliers List

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Related Products

Other Forms of 123171-59-5

Name CAS No Formula MW
Cefepime 88040-23-7 C19H24N6O5S2 480.56

Recommended Compounds in Bacterial

Name CAS No Formula MW
Fidaxomicin 873857-62-6 C52H74Cl2O18 1058.04
AVX 13616 900814-48-4 C50H73Cl2N7O7 955.06
Bedaquiline (fumarate) 845533-86-0 C36H35BrN2O6 671.58
Mafenide (Acetate) 13009-99-9 C9H14N2O4S 246.28
Cefozopran 113359-04-9 C19H17N9O5S2 515.53
Azithromycin 83905-01-5 C38H72N2O12 748.9845
Pazufloxacin 127045-41-4 C16H15FN2O4 318.3
Pazufloxacin (mesylate) 163680-77-1 C17H19FN2O7S 414.4054
Capreomycin (sulfate) 1405-37-4 C24H44N14O12S 752.76
Bleomycin (sulfate) 9041-93-4 C110H168N34O46S7 2927.17
G-418 (disulfate) 108321-42-2 C20H44N4O18S2 692.71
Demeclocycline (hydrochloride) 64-73-3 C21H22Cl2N2O8 501.31
Apramycin 37321-09-8 C21H41N5O11 539.58
Ceftriaxone 73384-59-5 C18H18N8O7S3 554.58
Ceftibuten 97519-39-6 C15H14N4O6S2 410.42
Dapsone 80-08-0 C12H12N2O2S 248.3
Vancomycin 1404-90-6 C66H76Cl3N9O24 1485.72
Lomefloxacin 98079-51-7 C17H19F2N3O3 351.35
Dirithromycin 62013-04-1 C42H78N2O14 835.07
Mafenide 138-39-6 C7H10N2O2S 186.23

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Cefepime (Dihydrochloride Monohydrate)

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