• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

1405-37-4 (Capreomycin (sulfate))

1

Identification

Capreomycin (sulfate) Capreomycin (sulfate)
Name Capreomycin (sulfate)
Formula C24H44N14O12S
MW 752.76
CAS No. 1405-37-4
EINECS 215-776-8
Smiles O=C(NC[[email protected]](N)C(N[[email protected]]1CO)=O)[[email protected]@H](NC(/C(NC([[email protected]](CNC([[email protected]@H](N)CCCN)=O)NC1=O)=O)=C/NC(N)=O)=O)[[email protected]@H](CCN2)NC2=N.OS(O)(=O)=O
Synonyms (S)-2,5-diamino-N-(((2S,5S,11S,15S,Z)-15-amino-2-(hydroxymethyl)-11-((R)-2-iminohexahydropyrimidin-4-yl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-5-yl)methyl)pentanamide sulfate
InChI InChI=1S/C24H42N14O8.H2O4S/c25-4-1-2-10(26)17(40)32-7-13-19(42)34-14(8-33-24(29)46)20(43)38-16(12-3-5-30-23(28)37-12)22(45)31-6-11(27)18(41)36-15(9-39)21(44)35-13;1-5(2,3)4/h8,10-13,15-16,39H,1-7,9,25-27H2,(H,31,45)(H,32,40)(H,34,42)(H,35,44)(H,36,41)(H,38,43)(H3,28,30,37)(H3,29,33,46);(H2,1,2,3,4)/b14-8-;/t10-,11-,12+,13-,15-,16-;/m0./s1
2

Introduction

Capreomycin is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. IC50 value: Target: The drug should not be given with streptomycin or other drugs that may damage the auditory vestibular nerve.

Background Information

Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit. ......by AdooQ BioScience, LLC
Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit. ......by BOC Sciences
Capreomycin Sulfate, also known as HSDB-3211 and Capostatin, is a ribosomal subunit inbihitor used to treat tuberculosis. ......by MedKoo Biosciences, Inc.
A peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. ......by ProbeChem
Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit. ......by Selleck Chemicals LLC
Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit. ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000011661

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways Anti-infection
Target Bacterial
Research Area Infection
Indications HIV Infections Tuberculosis
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Capreomycin (sulfate) National Institute of Allergy and Infectious Diseases (NIAID) HIV Infections Tuberculosis 1999/11/2 2012/3/1 Phase 1 Clinical
Capreomycin (sulfate) - Launched
7

Safety Data of Capreomycin (sulfate)

´╗┐Hazard Symbols : T
´╗┐Risk Statements : 61-20/21/22
Safety Statements : 53-22-36/37/39-45
RTECS : EX8930000
WGKGermany : 3
8

Spectral Information

9

Suppliers List

10

Related Products

Other Forms of 1405-37-4

Name CAS No Formula MW

Recommended Compounds in Bacterial

Name CAS No Formula MW
Fidaxomicin 873857-62-6 C52H74Cl2O18 1058.04
AVX 13616 900814-48-4 C50H73Cl2N7O7 955.06
Bedaquiline (fumarate) 845533-86-0 C36H35BrN2O6 671.58
Mafenide (Acetate) 13009-99-9 C9H14N2O4S 246.28
Cefozopran 113359-04-9 C19H17N9O5S2 515.53
Azithromycin 83905-01-5 C38H72N2O12 748.9845
Pazufloxacin 127045-41-4 C16H15FN2O4 318.3
Pazufloxacin (mesylate) 163680-77-1 C17H19FN2O7S 414.4054
Bleomycin (sulfate) 9041-93-4 C110H168N34O46S7 2927.17
G-418 (disulfate) 108321-42-2 C20H44N4O18S2 692.71
Demeclocycline (hydrochloride) 64-73-3 C21H22Cl2N2O8 501.31
Apramycin 37321-09-8 C21H41N5O11 539.58
Ceftriaxone 73384-59-5 C18H18N8O7S3 554.58
Ceftibuten 97519-39-6 C15H14N4O6S2 410.42
Dapsone 80-08-0 C12H12N2O2S 248.3
Vancomycin 1404-90-6 C66H76Cl3N9O24 1485.72
Lomefloxacin 98079-51-7 C17H19F2N3O3 351.35
Dirithromycin 62013-04-1 C42H78N2O14 835.07
Cefepime (Dihydrochloride Monohydrate) 123171-59-5 C19H28Cl2N6O6S2 571.5
Mafenide 138-39-6 C7H10N2O2S 186.23

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Capreomycin (sulfate)

Tags: buy 1405-37-4 IC50 | 1405-37-4 price | 1405-37-4 cost | 1405-37-4 solubility | 1405-37-4 purchase | 1405-37-4 manufacturer | 1405-37-4 research buy | 1405-37-4 order | 1405-37-4 MSDS | 1405-37-4 chemical structure | 1405-37-4 Storage condition | 1405-37-4 molecular weight | 1405-37-4 mw | 1405-37-4 datasheet | 1405-37-4 supplier | 1405-37-4 cell line | 1405-37-4 NMR | 1405-37-4 MS | 1405-37-4 IR | 1405-37-4 solubility | 1405-37-4 Safe information | 1405-37-4 Qc and Spectral Information | 1405-37-4 Clinical Information | 1405-37-4 Clinical Trial | 1405-37-4 Route of Synthesis | 1405-37-4 storage condition | 1405-37-4 diseases and conditions | 1405-37-4 flash point | 1405-37-4 boiling point | 1405-37-4 melting point | 1405-37-4 storage condition | 1405-37-4 brand