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529-59-9 (Genistin)

1

Identification

Genistin Genistin
Name Genistin
Formula C21H20O10
MW 432.38
CAS No. 529-59-9
EINECS
Smiles O=C1C(C(O)=C2)=C(OC=C1C3=CC=C(O)C=C3)C=C2O[[email protected]@H]4O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]4O
Synonyms 4',5,7-Trihydroxyisoflavone 7-glucoside; Genistein 7-glucoside; Genistein-7-O-beta-D-glucopyranoside; 5-hydroxy-3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChI InChI=1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1
2

Introduction

Genistin is the major isoflavonoid of soybeans and soy products.

Background Information

Genistin is an isoflavone found in a number of dietary plants like soy and kudzu. It was shown to stimulate estrogen-dependent breast cancer cell growth in vivo. ......by AdooQ BioScience, LLC
An isoflavone glycoside found in soy-based products. Can be used as a negative control for the PTK inhibitor Genistein (Cat. No. 1533). ......by BioVision, Inc.,
Genistin is the major isoflavonoid of soybeans and soy products. ......by MedChemexpress Co., Ltd.
Genistin is a selective estrogen receptor modulator (SERM) found in soy. It is the less active glycoside analog of genistein. It acts as a phytoestrogen, induces cell cycle arrest and apoptosis in ovarian cancer cells, improves bone density and strength, and decreases myosin light chain kinase levels. ......by MedKoo Biosciences, Inc.
Actions Inactive analog of genistein; useful as a negative control for genistein and other tyrosine kinase inhibitors. Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT),with no measurable effect on mammalian or microbial DNA p ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000011649

Storage condition

Store desiccated at or below -20 oC. by LC Laboratoies

Solubility

10 mM in DMSO by CHEMSCENE, LLC
Soluble in DMSO. by LC Laboratoies
10 mM in DMSO by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways NF-κB Autophagy
Target Autophagy NF-κB
Research Area Others
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Genistin - Not Found
Genistin - No Development Reported
7

Safety Data of Genistin

Safety Statements : S22;S24/25
RTECS : DJ3093000
WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AA Blocks LLC
ALB Technology Limited 20mg/USD122() China
AOBIOUS INC USA
Abcam 10mg/USD118() USA
AdooQ BioScience, LLC USA
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
BLD Pharmatech
BOC Sciences
Baoji Herbest Bio-Tech Co., Ltd. 20mg/RMB500();1000mg/RMB2500() China
BioVision, Inc., 10mg/USD105() USA
Biochempartner Co., Ltd China
CHEMSCENE, LLC 50mg/USD80();100mg/USD115() USA
Carbosynth Limited 25mg/USD68();50mg/USD100();100mg/USD179();250mg/USD395();500mg/USD625()
Cayman Chemical Company 5mg/USD48();25mg/USD168() USA
Changsha Huir (CSHR) Biological-Tech Co., Ltd. China
Changsha Staherb Natural Ingredients Co., Ltd. China
EMD Millipore 5mg/USD146(In stock) USA
Fraken Biochem Co., Ltd. China
Jiangsu Alpha Hawk Chemicals Industrial Corp. China
LC Laboratoies 25mg/USD56(In stock);50mg/USD83(In stock);100mg/USD129(In stock);300mg/USD198(In stock);500mg/USD299(In stock);1g/USD392(In stock);2g/USD760(In stock);5g/USD1670(In stock) USA
MedChemexpress Co., Ltd. 5mg/USD50();10mg/USD65() USA
MedKoo Biosciences, Inc. USA
Phytomarker Ltd. China
Santa Cruz Biotechnology, Inc. USA
Selleck Chemicals LLC USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5mg/USD50();10mg/USD65() China
Shanghai SPE Chemicals Co., Ltd. China
Shannxi Huike Botanical Development Co., Ltd. China
Sichuan Xieli Pharmaceutical Co., Ltd. China
Sigma-Aldrich, Inc. 1mg/USD56() USA
Target Molecule Corp. 10mg/USD85();50mg/USD192();200mg/USD573() USA
Toronto Research Chemicals Inc. 50mg/USD1000() Canada
10

Related Products

Other Forms of 529-59-9

Name CAS No Formula MW

Recommended Compounds in Autophagy NF-κB

Name CAS No Formula MW
Pirarubicin (Hydrochloride) 95343-20-7 C32H38ClNO12 664.1
Berberine (chloride) 633-65-8 C20H18ClNO4 371.8142
DMH-1 1206711-16-1 C24H20N4O 380.44
CB-839 1439399-58-2 C26H24F3N7O3S 571.57
H-89 (dihydrochloride) 130964-39-5 C20H22BrCl2N3O2S 519.2826
Shikonin 517-89-5 C16H16O5 288.3
H 89 127243-85-0 C20H20BrN3O2S 446.36
Eupatilin 22368-21-4 C18H16O7 344.32
Isoalantolactone 470-17-7 C15H20O2 232.32
Scutellarein 529-53-3 C15H10O6 286.24
Leonurine 24697-74-3 C14H21N3O5 311.33
Berbamine (dihydrochloride) 6078-17-7 C37H42Cl2N2O6 681.6452
Ruxolitinib (S enantiomer) 941685-37-6 C17H18N6 306.37
D-Glucosamine (Hydrochloride) 66-84-2 C6H14ClNO5 215.63
Schizandrin A 61281-38-7 C22H28O6 388.45
Schisandrol B 58546-54-6 C23H28O7 416.46
Schisandrol A 7432-28-2 C24H32O7 432.51
Icaritin 118525-40-9 C21H20O6 368.3799
Bicyclol 118159-48-1 C19H18O9 390.34
Azithromycin 83905-01-5 C38H72N2O12 748.9845

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Genistin

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