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117976-90-6 (Rabeprazole (sodium))

1

Identification

Rabeprazole (sodium) Rabeprazole (sodium)
Name Rabeprazole (sodium)
Formula C18H20N3NaO3S
MW 381.42
CAS No. 117976-90-6
EINECS 222-630-7
Smiles [Na]N1C2=CC=CC=C2N=C1S(CC3=NC=CC(OCCCOC)=C3C)=O
Synonyms Aciphex sodium;LY307640 sodium; sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
InChI InChI=1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1
2

Introduction

Rabeprazole sodium(LY307640 sodium) is an antiulcer drug in the class of proton pump inhibitors. Target: Proton Pump Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell.

Background Information

Rabeprazole sodium is an antiulcer drug in the class of proton pump inhibitors. ......by AdooQ BioScience, LLC
The sodium salt form of Rabeprazole which is a partially reversible inhibitor of gastric proton pump and could be used in the treatment of sorts of gastrointestinal disease especially peptic ulcer. ......by BOC Sciences
Rabeprazole Sodium Salt is a partially reversible gastric proton pump inhibitor. Rabeprazole Sodium Salt is an inhibitor of ATP4. ......by MedKoo Biosciences, Inc.
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. ......by Selleck Chemicals LLC
Rebeprazole sodium is a proton pump inhibitor. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000011572

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways Membrane Transporter/Ion Channel
Target Proton Pump
Research Area Inflammation/Immunology
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Rabeprazole (sodium) - Launched
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Safety Data of Rabeprazole (sodium)

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Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AdooQ BioScience, LLC USA
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 10mg/USD60();50mg/USD119() USA
Cayman Chemical Company USA
Dimysh ( ShangHai ) Trading Co., Ltd. China
Hangzhou Deli Chemical Co., Ltd. China
MedChemexpress Co., Ltd. 10mg/USD60();50mg/USD119() USA
MedKoo Biosciences, Inc. USA
Selleck Chemicals LLC USA
Shanghai Haoyuan Chemexpress Co., Ltd. 10mg/USD60();50mg/USD119() China
Target Molecule Corp. 1mg/USD60();5mg/USD175() USA
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Related Products

Other Forms of 117976-90-6

Name CAS No Formula MW
Rabeprazole 117976-89-3 C18H21N3O3S 359.44

Recommended Compounds in Proton Pump

Name CAS No Formula MW
Rabeprazole 117976-89-3 C18H21N3O3S 359.44
Zinc Pyrithione 13463-41-7 C10H8N2O2S2Zn 317.69
Pantoprazole 102625-70-7 C16H15F2N3O4S 383.37
(R)-Lansoprazole 138530-94-6 C16H14F3N3O2S 369.36
Esomeprazole (magnesium salt) 1198768-91-0 C17H18MgN3O3S+ 368.71
Omeprazole 73590-58-6 C17H19N3O3S 345.42
Lansoprazole (sodium) 226904-00-3 C16H13F3N3NaO2S 391.34
Lansoprazole 103577-45-3 C16H14F3N3O2S 369.36
Picoprazole 78090-11-6 C17H17N3O3S 343.4
TAK-438 1260141-27-2 C21H20FN3O6S 461.46
Esomeprazole (sodium) 161796-78-7 C17H18N3NaO3S 367.4
Esomeprazole (Magnesium trihydrate) 217087-09-7 C34H42MgN6O9S2 767.17
(S)-Esomeprazole 119141-88-7 C17H19N3O3S 345.42
Chebulinic acid 18942-26-2 C41H32O27 956.68
Pantoprazole (sodium) 138786-67-1 C16H14F2N3NaO4S 405.3516
Esomeprazole potassium 161796-84-5 C17H18KN3O3S 383.51
Ilaprazole 172152-36-2 C19H18N4O2S 366.44
TAK-438 (free base) 881681-00-1 C17H16FN3O2S 345.3912
Pantoprazole (sodium hydrate) 164579-32-2 C16H14F2N3NaO4S 405.35
Omeprazole D3 922731-01-9 C17H16D3N3O3S 348.43

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Rabeprazole (sodium)

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