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| Smiles | OC1=CC(O)=C2C(OC3=CC(O)=C(O)C=C3C2=O)=C1[[email protected]@H]([[email protected]@H]([[email protected]@H](O)[[email protected]@H]4O)O)O[[email protected]@H]4CO |
|---|---|
| Synonyms | 1,3,6,7-tetrahydroxy-4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-9H-xanthen-9-one |
| InChI | InChI=1S/C19H18O11/c20-4-11-15(26)16(27)17(28)19(30-11)13-9(24)2-8(23)12-14(25)5-1-6(21)7(22)3-10(5)29-18(12)13/h1-3,11,15-17,19-24,26-28H,4H2/t11-,15-,16+,17-,19+/m1/s1 |
Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD.
| Isomangiferin, a natural product, has antiviral effect due to their capability of inhibiting virus replication within cells. ......by BOC Sciences |
| Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD. ......by ProbeChem |
| Appearance: | EBNumber:EB000011325 |
| 10 mM in DMSO | by CHEMSCENE, LLC |
| 10 mM in DMSO | by MedChemexpress Co., Ltd. |
| Product Name | Sponsor & Collaborators | Indications | Start Date | End Date | Phase |
|---|---|---|---|---|---|
| Isomangiferin | - | Not Found | |||
| Isomangiferin | - | No Development Reported |
| Company | Price and Availability | Country/Region |
|---|---|---|
| ALB Technology Limited | 10mg/USD368() | China |
| AOBIOUS INC | USA | |
| Apexbio Technology LLC | USA | |
| Ark Pharm, Inc. | USA | |
| AvaChem Scientific LLC | 5mg/USD490();10mg/USD790() | USA |
| BOC Sciences | 20mg/USD698(In stock) | |
| CHEMSCENE, LLC | 5mg/USD336();10mg/USD432() | USA |
| MedChemexpress Co., Ltd. | 5mg/USD336();10mg/USD432() | USA |
| ProbeChem | ||
| Shanghai Haoyuan Chemexpress Co., Ltd. | 5mg/USD336();10mg/USD432() | China |
| Wuhan ChemFaces Biochemical Co., Ltd. | 10mg/USD368() | China |
| Name | CAS No | Formula | MW |
|---|
| Name | CAS No | Formula | MW |
|---|---|---|---|
| (R)-(+)-Etomoxir (sodium salt) | 828934-41-4 | C15H18ClNaO4 | 320.74 |
| Dictamine | 484-29-7 | C12H9NO2 | 199.21 |
| 3,3',5-Triiodo-L-thyronine (sodium) | 55-06-1 | C15H11I3NNaO4 | 672.9553 |
| Fabomotizole (hydrochloride) | 173352-39-1 | C15H22ClN3O2S | 343.8721 |
| FPH2 | 957485-64-2 | C14H16ClN5O2S | 353.83 |
| α-Tocopherol (phosphate) | 38976-17-9 | C29H51O5P | 510.69 |
| BAMB-4 | 891025-25-5 | C15H12N2O2 | 252.27 |
| LDN-27219 | 312946-37-5 | C20H16N4O2S2 | 408.5 |
| ISO-1 | 478336-92-4 | C12H13NO4 | 235.24 |
| Aurothioglucose | 12192-57-3 | C6H11AuO5S | 392.18 |
| Oxybenzone | 131-57-7 | C14H12O3 | 228.24 |
| ITX3 | 347323-96-0 | C22H17N3OS | 371.45 |
| Cardiogreen | 3599-32-4 | C43H47N2NaO6S2 | 774.96 |
| Skp2 Inhibitor C1 | 432001-69-9 | C18H13BrN2O4S2 | 465.34 |
| INH1 | 313553-47-8 | C18H16N2OS | 308.4 |
| PF6-AM | 1268491-69-5 | C33H31BO12 | 630.4 |
| XEN445 | 1515856-92-4 | C18H17F3N2O3 | 366.33 |
| Disperse Blue 148 | 52239-04-0 | C19H19N5O4S | 413.45026 |
| Solvent Blue 35 | 17354-14-2 | C22H26N2O2 | 350.454 |
| CID-797718 | 370586-05-3 | C12H11NO3 | 217.2206 |
| Name | CAS No | Formula | MW |
|---|
