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470-17-7 (Isoalantolactone)

1

Identification

Isoalantolactone Isoalantolactone
Name Isoalantolactone
Formula C15H20O2
MW 232.32
CAS No. 470-17-7
EINECS
Smiles O=C1C([[email protected]@]2([H])C[[email protected]](C3=C)([H])[[email protected]@](CCC3)(C)C[[email protected]@]2([H])O1)=C
Synonyms (3aR,4aS,8aR,9aR)-8a-Methyl-3,5-dimethylene-decahydro-naphtho[2,3-b]furan-2-one; (3aR,4aS,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one
InChI InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h11-13H,1-2,4-8H2,3H3/t11-,12+,13-,15-/m1/s1
2

Introduction

Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.

Background Information

Isoalantolactone has the capacity to inhibit tumor cell growth through induction of apoptosis. ......by BOC Sciences
Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent. ......by MedChemexpress Co., Ltd.
Extracted from Inula helenium L.roots,I.Racemosa Hook.F.;Store the product in sealed, cool and dry condition ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000011317

Storage condition

Solubility

10 mM in DMSO by CHEMSCENE, LLC
10 mM in DMSO by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways NF-κB Autophagy
Target Keap1-Nrf2 Autophagy
Research Area Others
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Isoalantolactone - Not Found
Isoalantolactone - No Development Reported
7

Safety Data of Isoalantolactone

Hazard Symbols : Xn
Risk Statements : 40
Safety Statements : 22-36
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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
Alfa Chemistry USA
BOC Sciences
Baoji Herbest Bio-Tech Co., Ltd. China
CHEMSCENE, LLC 10mg/USD78();50mg/USD180() USA
Chengdu Chenguang Laboratories Ltd CHINA
MedChemexpress Co., Ltd. 10mg/USD78();50mg/USD180() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 10mg/USD78();50mg/USD180() China
Target Molecule Corp. 10mg/USD43();25mg/USD84();50mg/USD141();100mg/USD232() USA
10

Related Products

Other Forms of 470-17-7

Name CAS No Formula MW

Recommended Compounds in Keap1-Nrf2 Autophagy

Name CAS No Formula MW
CDDO-EA 932730-51-3 C33H46N2O3 518.73
RTA-408 1474034-05-3 C33H44F2N2O3 554.7108664
Gypenoside XVII 80321-69-3 C48H82O18 947.15
Nordihydroguaiaretic acid 500-38-9 C18H22O4 302.36
Curcumin 458-37-7 C21H20O6 368.38
Ezetimibe 163222-33-1 C24H21F2NO3 409.43
Dimethyl fumarate 624-49-7 C6H8O4 144.13
Bardoxolone 218600-44-3 C31H41NO4 491.66
Bardoxolone (methyl) 218600-53-4 C32H43NO4 505.69
Hinokitiol 499-44-5 C10H12O2 164.2
NK-252 1414963-82-8 C13H11N5O3 285.2581
Ezetimibe D4 1093659-90-5 C24H17D4F2NO3 413.45
Danshensu 76822-21-4 C9H10O5 198.17
ML385 846557-71-9 C31H29N3O2S 507.65
Cpd16 C24H22N2O6S2 498.57
Cpd16-AA C28H26N2O10S2 614.64
TBE-31 C21H18N2O2 330.38
AEM1 C20H14FN3O2S 379.41
Lyngbyabellin A C29H40Cl2N4O7S2 691.69
Grassypeptolide A C56H79N9O10S2 1102.41

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

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More Information

Isoalantolactone

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