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78821-43-9 (Epibrassinolide)

1

Identification

Epibrassinolide Epibrassinolide
Name Epibrassinolide
Formula C28H48O6
MW 480.68
CAS No. 78821-43-9
EINECS
Smiles C[[email protected]@]1([[email protected]@]2([H])[[email protected]](C)[[email protected]@H](O)[[email protected]](O)[[email protected]](C)C(C)C)[[email protected]](CC2)([H])[[email protected]@](COC3=O)([H])[[email protected]]([[email protected]@]4([[email protected]]3([H])C[[email protected]](O)[[email protected]](O)C4)C)([H])CC1
Synonyms 24-Epibrassinolide;B1105;BP55; (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-((2S,3R,4R,5R)-3,4-dihydroxy-5,6-dimethylheptan-2-yl)-5,6-dihydroxy-7a,9a-dimethyltetradecahydro-1H-benzo[c]indeno[5,4-e]oxepin-3(12bH)-one
InChI InChI=1S/C28H48O6/c1-14(2)15(3)24(31)25(32)16(4)18-7-8-19-17-13-34-26(33)21-11-22(29)23(30)12-28(21,6)20(17)9-10-27(18,19)5/h14-25,29-32H,7-13H2,1-6H3/t15-,16+,17+,18-,19+,20+,21-,22+,23-,24-,25-,27-,28-/m1/s1
2

Introduction

Epibrassinolide (EBR; B1105; 24-Epibrassinolide) is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family; was shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. IC50 value: Target: plant growth regulator; Apoptosis inducer in vitro: Induction of apoptotic cell death was observed in prostate cancer cell lines after EBR treatment.

Background Information

A member of the brassinosteroids which are plant hormones involved in metabolic manipulation and protection from environmental stress ......by BOC Sciences
Epibrassinolide is a natural brassinosteroid (BR) derivative, is a plant regulator with a similar structure to mammalian steroids. Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. ......by MedChemexpress Co., Ltd.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000010495

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Apoptosis
Target Apoptosis
Research Area Cancer
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Epibrassinolide - Not Found
Epibrassinolide - No Development Reported
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Safety Data of Epibrassinolide

WGKGermany : 3
8

Spectral Information

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Suppliers List

Company Price and Availability Country/Region
Apexbio Technology LLC USA
Ark Pharm, Inc. USA
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 5mg/USD60();10mg/USD84() USA
Cayman Chemical Company USA
China Shenghua Group Agrochemical Company China
Jintan Yufan Medicine Raw Materials Co., Ltd. China
MedChemexpress Co., Ltd. 5mg/USD60();10mg/USD84() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5mg/USD60();10mg/USD84() China
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Related Products

Other Forms of 78821-43-9

Name CAS No Formula MW

Recommended Compounds in Apoptosis

Name CAS No Formula MW
Columbianadin 5058-13-9 C19H20O5 328.36
NSC348884 81624-55-7 C38H40N10 636.79
SMIP004 143360-00-3 C13H19NO 205.3
Meisoindigo 97207-47-1 C17H12N2O2 276.29
Betulin 473-98-3 C30H50O2 442.72
Costunolide 553-21-9 C15H20O2 232.32
Baohuoside I 113558-15-9 C27H30O10 514.52
Bisdemethoxycucurmin 24939-16-0 C19H16O4 308.3279
Demethoxycurcumin 22608-11-3 C20H18O5 338.35
Cisplatin 15663-27-1 Cl2H6N2Pt 300.05
(E)-[6]-Dehydroparadol 878006-06-5 C17H24O3 276.3707
PM00104 308359-57-1 C37H38F3N3O8 709.71
Episilvestrol 697235-39-5 C34H38O13 654.66
Trabectedin 114899-77-3 C39H43N3O11S 761.84
Myricetin 529-44-2 C15H10O8 318.2351
Adarotene 496868-77-0 C25H26O3 374.47
(±)-[6]-Gingerol 39886-76-5 C17H26O4 294.3859
Betulinic acid 472-15-1 C30H48O3 456.7
Silvestrol aglycone 960365-65-5 C27H26O8 478.4905
Elesclomol 488832-69-5 C19H20N4O2S2 400.52

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Epibrassinolide

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