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55-06-1 (3,3',5-Triiodo-L-thyronine (sodium))

1

Identification

3,3',5-Triiodo-L-thyronine (sodium) 3,3',5-Triiodo-L-thyronine (sodium)
Name 3,3',5-Triiodo-L-thyronine (sodium)
Formula C15H11I3NNaO4
MW 672.9553
CAS No. 55-06-1
EINECS 200-223-5
Smiles [O-]C([[email protected]](CC1=CC(I)=C(C(I)=C1)OC2=CC=C(O)C(I)=C2)N)=O.[Na+]
Synonyms T3 Sodium salt;Sodium L-3,3',5-triiodothyronine;Liothyronine sodium
InChI InChI=1S/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/m0./s1
2

Introduction

3,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.

Background Information

Thyroid hormone (T3) analog ......by AOBIOUS INC
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. ......by BOC Sciences
3,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity. ......by MedChemexpress Co., Ltd.
Liothyronine sodium is a metabolite of THYROXINE, formed by the peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus. It is also a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. ......by MedKoo Biosciences, Inc.
Liothyronine is a synthetic form of thyroid hormone (T3) used to treat hypothyroidism and myxedema coma. It is also used as an augmentation strategy in treating Major Depressive Disorder when used in combination with antidepressants. It is marketed as the sodium salt under the brand name Cytomel (or Tertroxin in Australia). ......by MedKoo Biosciences, Inc.
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. ......by Selleck Chemicals LLC
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. ......by Target Molecule Corp.
Thyroid hormone (T3) analog. Promotes differentiation of mesenchymal stem cells (MSCs) into adipogenic cells in vitro. ......by Tocris Bioscience Inc.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000010067

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Others
Target Others
Research Area Endocrinology
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
3,3',5-Triiodo-L-thyronine (sodium) - Launched
7

Safety Data of 3,3',5-Triiodo-L-thyronine (sodium)

Hazard Symbols : Xn
Risk Statements : 20/21/22
Safety Statements : S24/25
WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AOBIOUS INC USA
Ark Pharm, Inc. USA
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 100mg/USD60();500mg/USD144() USA
Cayman Chemical Company 100mg/USD35() USA
EMD Millipore 250mg/USD72() USA
MedChemexpress Co., Ltd. 100mg/USD60();500mg/USD144() USA
MedKoo Biosciences, Inc. USA
MedKoo Biosciences, Inc. USA
Santa Cruz Biotechnology, Inc. 250mg/USD111() USA
Selleck Chemicals LLC USA
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD60();500mg/USD144() China
Sigma-Aldrich, Inc. 100mg/USD55() USA
Spectrum Chemical Mfg. Corp. 100mg/USD88() USA
Suchem Pharma Co., Ltd. China
Suzhou Chemland Pharmaceutical & Technologies Co., Ltd. China
Target Molecule Corp. 2mg/USD20();10mg/USD80();50mg/USD135() USA
Tocris Bioscience Inc. 50mg/USD35() USA
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Related Products

Other Forms of 55-06-1

Name CAS No Formula MW
3,3',5-Triiodo-L-thyronine 6893-02-3 C15H12I3NO4 650.9735

Recommended Compounds in Others

Name CAS No Formula MW
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 320.74
Dictamine 484-29-7 C12H9NO2 199.21
Fabomotizole (hydrochloride) 173352-39-1 C15H22ClN3O2S 343.8721
FPH2 957485-64-2 C14H16ClN5O2S 353.83
α-Tocopherol (phosphate) 38976-17-9 C29H51O5P 510.69
BAMB-4 891025-25-5 C15H12N2O2 252.27
LDN-27219 312946-37-5 C20H16N4O2S2 408.5
ISO-1 478336-92-4 C12H13NO4 235.24
Aurothioglucose 12192-57-3 C6H11AuO5S 392.18
Oxybenzone 131-57-7 C14H12O3 228.24
ITX3 347323-96-0 C22H17N3OS 371.45
Cardiogreen 3599-32-4 C43H47N2NaO6S2 774.96
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 465.34
INH1 313553-47-8 C18H16N2OS 308.4
PF6-AM 1268491-69-5 C33H31BO12 630.4
XEN445 1515856-92-4 C18H17F3N2O3 366.33
Disperse Blue 148 52239-04-0 C19H19N5O4S 413.45026
Solvent Blue 35 17354-14-2 C22H26N2O2 350.454
CID-797718 370586-05-3 C12H11NO3 217.2206
CP-640186 (hydrochloride) 591778-70-0 C30H36ClN3O3 522.08

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

3,3',5-Triiodo-L-thyronine (sodium)

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