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BOC Sciences

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Basic Information

Company Name:BOC Sciences

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Year Established: 2005

Introduction of BOC Sciences

BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.

Web: www.bocsci.com TEL:1-631-504-6093 Fax:1-631-614-7828 Email:[email protected]

Products of BOC Sciences

  • Chemical Name: Docetaxel Impurity B (10-Oxo Docetaxel)
    CAS No.: 167074-97-7 Purity: >98% Appearances:
    Brand:BOC Sciences Synonyms: (2aR,4S,4aS,9R,11S,12R,12aR... Quality Control & MSDS Files:
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    Brief introduction:

    A novel taxoid having remarkable anti-tumor properties. Docetaxel intermediate. This product is unstable in solution, epimerize.

  • Chemical Name: PSN632408
    CAS No.: 857652-30-3 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: PSN 632408;PSN-632408; tert... Quality Control & MSDS Files:
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    Brief introduction:

    PSN632408 is an optimized agonist of GPR119 receptors that shows similar potency to OEA at both recombinant mouse and human GPR119 receptors. It suppresses food intake, reduces weight gain, and white adipose tissue deposition in rats. It may be useful as

  • Chemical Name: AVX 13616
    CAS No.: 900814-48-4 Purity: >98% Appearances:
    Brand:BOC Sciences Synonyms: AVX13616;AVX-13616; isopent... Quality Control & MSDS Files:
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    Brief introduction:

    AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate, particularly against drug-resistant Staphylococcus pathogens. It was as active as mupirocin in a nasal decolonization model but required only a single appli

  • Chemical Name: Talabostat mesylate
    CAS No.: 150080-09-4 Purity: 98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: [(2R)-1-[(2S)-2-Amino-3-met... Quality Control & MSDS Files:
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    Brief introduction:

    Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such a

  • Chemical Name: Oxybenzone
    CAS No.: 131-57-7 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: 2-Hydroxy-4-methoxybenzophe... Quality Control & MSDS Files:
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    Brief introduction:

    2-Hydroxy-4-methoxybenzophenone (benzophenone-3) is commonly employed as broad-band UV-filter in sunscreen cosmetic products. It protects skin from the deleterious effects of the sun. It is one of the sunscreen constituent and its trace determination in w

  • Chemical Name: CFTRinh-172
    CAS No.: 307510-92-5 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: CFTR Inhibitor-172;CFTRinh-... Quality Control & MSDS Files:
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    Brief introduction:

    CFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters.

  • Chemical Name: Dafadine-A
    CAS No.: 1065506-69-5 Purity: 98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: Dafadine A; (5-((2,6-dimeth... Quality Control & MSDS Files:
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    Brief introduction:

    Dafadine-A, the first identified chemical inhibitor of DAF-9, could restrain the dauer formation, developmental timing and longevity in the nematodeCaenorhabditis elegans.

  • Chemical Name: Mcl1-IN-1
    CAS No.: 713492-66-1 Purity: ≥95% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: 2-(2-((5-chloro-8-hydroxyqu... Quality Control & MSDS Files:
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    Brief introduction:

    Mcl1-IN-1 is a potent Mcl-1-selective inhibitor with IC50 of 2.4 uM, relative to the related Bcl-2 family protein Bcl-xL.

  • Chemical Name: Tyrphostin A1
    CAS No.: 2826-26-8 Purity: Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: Tyrphostin 1;AG9; 2-(4-meth... Quality Control & MSDS Files:
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    Brief introduction:

    Tyrphostin A1, can be as a negative control for inhibition of EGFR (IC50 >1250 ?M) and was shown to inhibit the tyrosine phosphorylation of IL-2 stimulated Tyk-2 in plemented with 20% LADMAC supernatant.

  • Chemical Name: Tolazoline
    CAS No.: 59-98-3 Purity: ≥95% Appearances:
    Brand:BOC Sciences Synonyms: 2-Benzylimidazoline; 2-Benz... Quality Control & MSDS Files:
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    Brief introduction:

    Tolazoline is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn..

  • Chemical Name: HLM006474
    CAS No.: 353519-63-8 Purity: >98% Appearances:
    Brand:BOC Sciences Synonyms: HLM 006474;HLM-006474; 7-((... Quality Control & MSDS Files:
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    Brief introduction:

    HLM 006474 acts as an E2F transcription factor inhibitor, preventing DNA binding activity. This results in the induction of apoptosis in breast cancer cells.

  • Chemical Name: 3CAI
    CAS No.: 28755-03-5 Purity: >98% Appearances:
    Brand:BOC Sciences Synonyms: 3 CAI;3-CAI; 2-chloro-1-(1H... Quality Control & MSDS Files:
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    Brief introduction:

    3CAI is an orally active, potent and specific allosteric inhibitor of Akt1 and Akt2 that directly binds to Ak1 and Akt2 in an ATP noncompetitive manner.

  • Chemical Name: iCRT 14
    CAS No.: 677331-12-3 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: iCRT14;iCRT-14; (Z)-5-((2,5... Quality Control & MSDS Files:
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    Brief introduction:

    iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT). It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.

  • Chemical Name: SJ 172550
    CAS No.: 431979-47-4 Purity: ≥98 % Appearances: Pink to red Solid
    Brand:BOC Sciences Synonyms: SJ172550;SJ 172550; (E)-met... Quality Control & MSDS Files:
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    Brief introduction:

    SJ 172550 is a MDMX inhibitor (EC50 = 2.3 μM), controls the biological activity of MDMX.

  • Chemical Name: ITX3
    CAS No.: 347323-96-0 Purity: >98% Appearances:
    Brand:BOC Sciences Synonyms: ITX 3;ITX-3; (E)-2-((2,5-di... Quality Control & MSDS Files:
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    Brief introduction:

    ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation of TrioN-dependent cell struct

  • Chemical Name: pentafluorophenol
    CAS No.: 771-61-9 Purity: 96.0% Appearances:
    Brand:BOC Sciences Synonyms: 2,3,4,5,6-Pentafluorophenol... Quality Control & MSDS Files:
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  • Chemical Name: DMH-1
    CAS No.: 1206711-16-1 Purity: 0.98 Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: DMH1;DMH 1; 4-(6-(4-isoprop... Quality Control & MSDS Files:
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    Brief introduction:

    DMH-1 is a second-generation small molecule BMP inhibitor based on dorsomorphin. DMH-1 effectively inhibits the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM). Treatment with DMH1 reduced lung metastasis and the tumors were less proliferativ

  • Chemical Name: Oncrasin-1
    CAS No.: 75629-57-1 Purity: >98% Appearances: Light yellow to earth yellow Solid
    Brand:BOC Sciences Synonyms: Oncrasin 1;Oncrasin1; 1-(4-... Quality Control & MSDS Files:
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    Brief introduction:

    Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations. It also led to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistan

  • Chemical Name: Skp2 Inhibitor C1
    CAS No.: 432001-69-9 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: SKPin C1; (Z)-2-(4-bromo-2-... Quality Control & MSDS Files:
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    Brief introduction:

    Skp2 Inhibitor C1(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation, selectively inhibits Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts.

  • Chemical Name: T-5224
    CAS No.: 530141-72-1 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: T5224;T 5224; 3-(5-(4-(cycl... Quality Control & MSDS Files:
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    Brief introduction:

    T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II hum