• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

BOC Sciences

34221

Basic Information

Company Name:BOC Sciences

Business Type:

Total NO.Employees:

Country/Region:

Certificates:

Year Established: 2005

Introduction of BOC Sciences

BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.

Web: www.bocsci.com TEL:1-631-504-6093 Fax:1-631-614-7828 Email:[email protected]

Products of BOC Sciences

  • Chemical Name: AMG 837 calcium hydrate
    CAS No.: 1259389-38-2 Purity: 0.98 Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: AMG-837 calcium hydrate;AMG... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    AMG 837 calcium hydrate is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.

  • Chemical Name: AMG 837 sodium salt
    CAS No.: 865231-45-4 Purity: >98% Appearances:
    Brand:BOC Sciences Synonyms: AMG-837 sodium salt;AMG837 ... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    AMG 837 sodium salt is a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. It displayed the expected two-fold increase in potency on GPR4 compared to the racemic compound

  • Chemical Name: PEAQX
    CAS No.: 459836-30-7 Purity: 0.98 Appearances:
    Brand:BOC Sciences Synonyms: NVP-AAM077 Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    PEAQX(NVP-AAM 077) is a potent and orally active NMDA antagonist with a 15-fold preference for human NMDA receptors with the 1A/2A(IC50=270 nM), rather than 1A/2B(29,600 nM).

  • Chemical Name: LY2857785
    CAS No.: 1619903-54-6 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: LY 2857785;LY-2857785; (1r,... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.

  • Chemical Name: H-4-Phenyl-D-Phe-OH
    CAS No.: 170080-13-4 Purity: 99% Appearances:
    Brand:BOC Sciences Synonyms: 4-Phenyl-D-phenyalanine; (R... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

  • Chemical Name: H-4-Phenyl-Phe-OH
    CAS No.: 155760-02-4 Purity: 99% Appearances:
    Brand:BOC Sciences Synonyms: 4-Phenyl-L-phenyalanine; (S... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

  • Chemical Name: (R)-((addition))-Etomoxir sodium salt
    CAS No.: 828934-41-4 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    (R)-((addition))-Etomoxir sodium salt is a potent inhibitor of carnitine palmitoyltransferase I (CPT1), which inhibits β-oxidation in mitochondria. It has shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    IM-12 is a selective GSK-3β inhibitor with IC50 of 53 nM, and also enhances canonical Wnt signalling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: 0.98 Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM). Nexturastat A possesses antiproliferative effects against melanoma cells. Histone deacetylases (HDACs)

  • Chemical Name: kb-NB77-78
    CAS No.: 1350622-33-1 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: 9-((tert-butyldimethylsilyl... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).

  • Chemical Name: MMAD hydrochloride
    CAS No.: 173441-26-4 Purity: >98% Appearances: White to off-white solid
    Brand:BOC Sciences Synonyms: Demethyldolastatin 10 hydro... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    For comparison purposes, the ADC A1 -mc-MMAD and/or A1 -vc-MMAD were used. The linker payload, mc-MMAD (6-maleimidocaproyl-monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately

  • Chemical Name: Boc-Phe-OH
    CAS No.: 13734-34-4 Purity: Appearances:
    Brand:BOC Sciences Synonyms: BOC-L-Phenylalanine;N-(tert... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

  • Chemical Name: HG6-64-1
    CAS No.: 1315329-43-1 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: HG-6-64-1;HG 6-64-1; (E)-N-... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738.

  • Chemical Name: 4SC-202
    CAS No.: 910462-43-0 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: 4SC 202 free base;4SC202 fr... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an acc

  • Chemical Name: Dictamnine
    CAS No.: 484-29-7 Purity: >98% Appearances: Light yellow to yellow Solid
    Brand:BOC Sciences Synonyms: 4-Methoxyfuro[2,3-b]quinoli... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Dictamnine has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; It has been reported to have antimicrobial activity against bacteria and fungi.

  • Chemical Name: Arg-Gly-Asp-Ser
    CAS No.: 91037-65-9 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: RGDS peptide;Fibronectin In... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibitio

  • Chemical Name: Defactinib
    CAS No.: 1073154-85-4 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Defactinib, also known as VS-6063 and PF-04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor PF-04554878 inhibits FAK, which may prevent the

  • Chemical Name: Ozanimod (RPC1063)
    CAS No.: 1306760-87-1 Purity: 99% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: RPC-1063 Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Ozanimod (RPC1063) is a selective oral S1P Receptor 1 modulator. Phase 3.

  • Chemical Name: YH239-EE
    CAS No.: 1364488-67-4 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: YH 239-EE;YH 239 EE; ethyl ... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    YH239-EE inhibits the growth of OCI-AML-3 cells with wild type p53 by inhibiting the p53-MDM2 interaction.

  • Chemical Name: PI-1840
    CAS No.: 1401223-22-0 Purity: >98% Appearances: White to off-white Solid
    Brand:BOC Sciences Synonyms: PI 1840;PI1840; N-isopropyl... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    PI-1840 potently inhibits proteasomal CT-L activity with IC50 of 0.37 μM in intact human MDA-MB-468 cancer cells, and inhibits proliferation/survival of human MDA-MB-468 cells.