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Adipogen Corporation

1822

Basic Information

Company Name:Adipogen Corporation

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Country/Region:USA

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Introduction of Adipogen Corporation

Web: www.adipogen.com TEL:(858) 457-8383 Fax:(858) 457-8484 Email:[email protected]

Products of Adipogen Corporation

  • Chemical Name: (+)-Etomoxir . sodium salt
    CAS No.: 828934-41-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
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    Irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1a) a mitochondrial enzyme involved in fatty acid β-oxidation. CPR-1a on the outer face of the inner mitochondrial membrane, consequently prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the in...

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =5.02nM). Displays high selectivity over all other HDACs (IC50=3-10µM). Suppresses cell proliferation and promotes apoptosis in B16 cells (GI50=14.3µM) and human lymphoma cells HuT-78. Dose-dependently induces hyperacetylation of α-tubulin in B16 murine melanoma cell...

  • Chemical Name: PI-1840 [Proteasome Inhibitor]
    CAS No.: 1401223-22-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PI 1840;PI1840; N-isopropyl... Quality Control & MSDS Files:
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    Highly potent, selective and rapidly reversible non-covalent proteasome inhibitor. Targets the chymotrypsin-like β5-subunit of the constitutive 20S proteasome (IC50=27nM), with minimal cross-reactivity on the trypsin-like (β2) and caspase-like/postglutamyl-peptide-hydrolysis-like (β1) proteolytic activity (IC50= >100μM, for both). Exh...

  • Chemical Name: AZ191
    CAS No.: 1594092-37-1 Purity: Appearances: light yellow to khaki Solid
    Brand: Synonyms: AZ 191; N-(2-methoxy-4-(4-m... Quality Control & MSDS Files:
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    Cell permeable azaindole that inhibits the serine/threonine kinase activity of DYRK1B (IC50=17nM) with 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively. Used as a probe to elucidate the mechanism of DYRK1B regulation of cell cycle progression. Dual-specificity tyrosine-(Y)-phosphorylat...

  • Chemical Name: MI-2 [MALT1 Inhibitor]
    CAS No.: 1047953-91-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: MALT1 inhibitor Quality Control & MSDS Files:
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    Highly potent and selective irreversible MALT1 inhibitor (IC50=5.8μM). Binds directly to MALT1 and suppresses protease function. Decreases NF-κB activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 (EC50= ~200nM and ~500nM for HBL-1 and TMD8, respectively) activat...

  • Chemical Name: AK-7
    CAS No.: 420831-40-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AK 7;AK7; 3-(azepan-1-ylsul... Quality Control & MSDS Files:
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    Brain-permeable SIRT2 (sirtuin 2) inhibitor.

  • Chemical Name: Berberine chloride
    CAS No.: 633-65-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: BBR;Umbellatine Quality Control & MSDS Files:
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    An isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic leukemia (ALL) cells with both MDM2 overexpression and a wild-type (wt)-p53, whereas no pro-apoptotic effect was detected in ALL cells th...

  • Chemical Name: Z-VAD-FMK (Cell permeable)
    CAS No.: 187389-52-2 and 634911-81-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Z-Val-Ala-Asp(OMe)-FMK Quality Control & MSDS Files:
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    Cell permeable, non-selective broad-spectrum caspase inhibitor [1, 3, 7, 8]. Binds irreversibly to the catalytic site of caspase proteases [1]. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability [1]. Inhibits ICE-family protease/caspase processing, leading to ...

  • Chemical Name: SB 366791
    CAS No.: 472981-92-3 Purity: Appearances: off-white
    Brand: Synonyms: SB366791;SB-366791; 3-(4-ch... Quality Control & MSDS Files:
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  • Chemical Name: GW311616A . hydrochloride
    CAS No.: 197890-44-1 Purity: Appearances:
    Brand: Synonyms: GW-311616 hydrochloride;GW ... Quality Control & MSDS Files:
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    Potent, selective intracellular neutrophil elastase (NE, α-1-proteinase) inhibitor (by covalently binding to NE). Inhibits human neutrophil elastase (HNE) and is selective over other human serine proteases with IC50 values of 22nM for HNE, >100μM for trypsin, cathepsin G and plasmin, >3μM for chymotrypsin and tissue plasminogen activa...

  • Chemical Name: Palbociclib isethionate
    CAS No.: 827022-33-3 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: PD0332991 isethionate;PD-03... Quality Control & MSDS Files:
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    Palbociclib isethionate(PD-0332991 isethionate) is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases. IC50 value: 11 nM/16 nM (Cdk4/Cdk6) [1] Target: Cdk4/Cdk6 in vitro: ATP competitive inhibitor of Cdk4.

  • Chemical Name: IWR-1-endo
    CAS No.: 1127442-82-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: endo-IWR 1;IWR-1-endo;IWR1;... Quality Control & MSDS Files:
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    Potent and reversible cell permeable Wnt pathway signaling inhibitor [1, 2, 4, 5]. Inhibits Wnt-induced accumulation of β-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3β. Stabilizes the destruction complex, increasing the level of Axin2 protein with...

  • Chemical Name: 6-ECDCA
    CAS No.: 459789-99-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Obeticholic acid;6-ECDCA;6-... Quality Control & MSDS Files:
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    Potent and selective FXR agonist (EC50= 99nM) [1]. Induces SHP in HSCs to suppress TIMP-1 expression [2]. Apoptosis inducer [2]. Protects against liver fibrosis development in rat in vivo [2]. Displays anticholeretic activity in rat in vivo [3]. Promotes preadipocyte differentiation [4]. Regulates adipogenesis and insulin signali...

  • Chemical Name: Tris(hydroxymethyl)aminomethane
    CAS No.: 77-86-1 Purity: Appearances: white
    Brand: Synonyms: THAM;Pehanorm;Trisamin;TAM Quality Control & MSDS Files:
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    Trometamol is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins.

  • Chemical Name: Safranin O
    CAS No.: 477-73-6 Purity: Appearances:
    Brand: Synonyms: C.I. 50240; Safranine O; 3,... Quality Control & MSDS Files:
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  • Chemical Name: Gram's Safranin Solution
    CAS No.: 477-73-6 Purity: Appearances:
    Brand: Synonyms: C.I. 50240; Safranine O; 3,... Quality Control & MSDS Files:
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  • Chemical Name: Arsenazo III
    CAS No.: 1668-00-4 Purity: Appearances:
    Brand: Synonyms: 3,6-bis((E)-(2-arsonophenyl... Quality Control & MSDS Files:
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  • Chemical Name: Phenol red sodium salt
    CAS No.: 34487-61-1 Purity: Appearances:
    Brand: Synonyms: sodium 4-(3-(4-hydroxypheny... Quality Control & MSDS Files:
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    Phenol Red sodium salt is a water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range.

  • Chemical Name: ZnAF-2F DA Solution
    CAS No.: 443302-10-1 Purity: Appearances:
    Brand: Synonyms: ZnAF2F DA;ZnAF 2F DA; 6-((2... Quality Control & MSDS Files:
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  • Chemical Name: ZnAF-2F DA
    CAS No.: 443302-10-1 Purity: Appearances:
    Brand: Synonyms: ZnAF2F DA;ZnAF 2F DA; 6-((2... Quality Control & MSDS Files:
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