• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

EMD Millipore

284

Basic Information

Company Name:EMD Millipore

Business Type:

Total NO.Employees:19000

Country/Region:USA

Certificates:

Year Established:

Introduction of EMD Millipore

In late 2015, EMD Millipore joined forces with Sigma-Aldrich. Our combined organization, which operates as MilliporeSigma in the United States and Canada, is the life science business of Merck KGaA, Darmstadt, Germany – and a global leader in the $125 billion life science industry. Our shared purpose is to solve the toughest problems in life science by collaborating with the global scientific community. Together, we offer a broad portfolio of more than 300,000 products, including many of the most highly respected brands in the industry. Our offerings span every step of the biotech/biopharma production chain, creating a complete end-to-end workflow with enhanced customer service, a simplified interface and a leading e-commerce and distribution platform. MilliporeSigma operates 65 manufacturing sites worldwide and employs more than 19,000 people in 66 countries. This geographic reach, combined with our innovative portfolio, industry-leading capabilities, and a culture that fosters c

Web: www.emdmillipore.com TEL: Fax: Email:

Products of EMD Millipore

  • Chemical Name: 3,3',5-Triiodo-L-thyronine (sodium)
    CAS No.: 55-06-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: T3 Sodium salt;Sodium L-3,3... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    3,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to <b>β1 thyroid hormone receptor</b> (<b>TRβ1</b>), and activates its activity.

  • Chemical Name: ISO-1
    CAS No.: 478336-92-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: ISO 1;ISO1;MIF Antagonist; ... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    ISO-1 is an inhibitor of MIF d-dopachrome tautomerase activity with an IC50 of about 7 uM. IC50 value: 7 uM [1] Target: MIF inhibitor in vitro: ISO-1 inhibited MIF tautomerase activity in a dose-dependent manner with an IC50 of about 7 μM, but the non-hydroxylated phenyl analog (compound 2) was 10–15 times less potent.

  • Chemical Name: BTS
    CAS No.: 1576-37-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N-Benzyl-p-toluenesulfonami... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility.

  • Chemical Name: FR 180204
    CAS No.: 865362-74-9 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: FR 180204;FR-180204; 5-(2-p... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively. IC50 value: 0.31 uM/0.14 uM(Ki for ERK1/ERK2); 0.51uM/0.33 μM(ERK1/ERK2) [1] [2] Target: ERK1/2 inhibitor in vi...

  • Chemical Name: CFTR(inh)-172
    CAS No.: 307510-92-5 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: CFTR Inhibitor-172;CFTRinh-... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    CFTR(inh)-172 is an reversibly inhibitor of CFTR short-circuit current in less than 2 minutes in a voltage-independent manner with Ki approximately 300 nM.

  • Chemical Name: Tyrphostin A1
    CAS No.: 2826-26-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Tyrphostin 1;AG9; 2-(4-meth... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Tyrphostin A1(AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells. IC50 value: Target: IL-12 production inhibitor Addition of increasing concentration of A1 resulted in a dose dependent decrease of IL-12 p40, with maximal inhibition (62.5%) occurring at a dose of 10 μM.

  • Chemical Name: HLM006474
    CAS No.: 353519-63-8 Purity: Appearances:
    Brand: Synonyms: HLM 006474;HLM-006474; 7-((... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    HLM006474 is a potent inhibitor of melanocytes proliferation and subsequent invasion in a three-dimensional tissue culture model system; interferes with E2F activity. IC50 value: 29.8 μM(EC50 in vivo) Target: E2F inhibitor in vivo: HLM006474 is not specific to E2F4 and appears to inhibit binding by all E2F complexes.

  • Chemical Name: 3CAI
    CAS No.: 28755-03-5 Purity: Appearances:
    Brand: Synonyms: 3 CAI;3-CAI; 2-chloro-1-(1H... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    3CAI is a potent allosteric and specific AKT inhibitor, which exerts efficacy in vitro and in vivo. IC50 value: Target: Akt in vitro: 3CAI (1 μM) suppressed only AKT1 kinase activity and the other kinases tested were not affected by 3CAI.

  • Chemical Name: SJ-172550
    CAS No.: 431979-47-4 Purity: Appearances: Pink to red Solid
    Brand: Synonyms: SJ172550;SJ 172550; (E)-met... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    SJ-172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified. IC50 value: 0.84 uM(EC50) [1] Target: MDMX inhibitor in vitro: Unlike SJ-134433 and SJ-044557, SJ-172550 was stable in solution and did not modify the MDMX prot...

  • Chemical Name: ITX3
    CAS No.: 347323-96-0 Purity: Appearances:
    Brand: Synonyms: ITX 3;ITX-3; (E)-2-((2,5-di... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    ITX3 is a specific and nontoxic inhibitor of the TrioN (N-terminal GEF domain of the multidomain Trio protein) with IC50 of 76 uM; inhibits TrioN-stimulated RhoG exchange in vitro. IC50 value: 76 uM [1] Target: TrioN inhibitor In transfected mammalian cells, ITX3 blocked TrioN-mediated dorsal membrane ruffling and Rac1 activation w...

  • Chemical Name: DMH-1
    CAS No.: 1206711-16-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: DMH1;DMH 1; 4-(6-(4-isoprop... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2/3 respectively; inactive on ALK5, BMPR2, AMPK and VEGFR2. IC50 value: 27/107.9/<5 nM(ALK1/2/3) [1] Target: ALK inhibitor DMH-1 shows the most selectivity within these three compounds(LDN-193189, DMH-1 and dorsomorphin) [1].

  • Chemical Name: Oncrasin-1
    CAS No.: 75629-57-1 Purity: Appearances: Light yellow to earth yellow Solid
    Brand: Synonyms: Oncrasin 1;Oncrasin1; 1-(4-... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations; also led to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant cells. IC50 value: 1.0 μM(A549, K-ras 12H and p53 Wt) [1] Target: human lung can...

  • Chemical Name: Skp2 Inhibitor C1
    CAS No.: 432001-69-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: SKPin C1; (Z)-2-(4-bromo-2-... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Skp2 Inhibitor C1(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation, selectively inhibited Skp2-mediated p27 degradation by reducing p27binding through key compound-receptor contacts. IC50 value: Target: Skp2 inhibitor; p27 regulator in vitro: T47D cells treated with C1 (5 μM for 16 hours) displayed ...

  • Chemical Name: INH1
    CAS No.: 313553-47-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: IBT13131; N-(4-(2,4-dimethy... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    INH1 is a small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. IC50 value: 10-21 uM (GI50 in human breast cancer cell lines) [1] Target: Hec1 inhibitor Treating cells with INH1 triggered reduction of kinetochore-bound Hec1 as well as global Nek2 protein level, consequently lea...

  • Chemical Name: Z-VAD(OMe)-FMK
    CAS No.: 187389-52-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Z-Val-Ala-Asp(OMe)-FMK Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Z-VAD(OMe)-FMK is a cell-permeable, <b>pan-caspase</b> inhibitor.

  • Chemical Name: Dansyl chloride
    CAS No.: 605-65-2 Purity: Appearances: yellow to orange
    Brand: Synonyms: 5-(Dimethylamino)naphthalen... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

  • Chemical Name: Shikonin
    CAS No.: 517-89-5 Purity: Appearances:
    Brand: Synonyms: 5,8-Dihydroxy-2-[(1R)-1-hyd... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Shikonin is an inhibitor of <b>TMEM16A chloride channel</b> with an <b>IC<sub>50</sub></b> of 6.5 μM. Shikonin is also a specific inhibitor of <b>PKM2</b> and can also inhibit tumor necrosis factor-α (<b>TNF-α</b>) and prevent activation of nuclear factor-κB (<b>NF-κB</b>) pathway.

  • Chemical Name: D-Glucosamine (Hydrochloride)
    CAS No.: 66-84-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-Amino-2-deoxy-D-glucopyra... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Glucosamine is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, also presents in the shells of shellfish, animal bones, bone marrow, and fungi. Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.

  • Chemical Name: Genistin
    CAS No.: 529-59-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4',5,7-Trihydroxyisoflavone... Quality Control & MSDS Files:
    Price and Availability:
    Brief introduction:

    Genistin is the major isoflavonoid of soybeans and soy products.

<Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 ... Next>