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BioVision, Inc.,

2481

Basic Information

Company Name:BioVision, Inc.,

Business Type:

Total NO.Employees:

Country/Region:USA

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Year Established:

Introduction of BioVision, Inc.,

BioVision, Inc., is a privately held Life Science company headquartered in the beautiful San Francisco Bay area. BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, etc. BioVision’s products are currently being sold in more than 60 countries worldwide.

Web: www.biovision.com TEL:408-493-1800 Toll Free: 800-891-9699 (US Only) Fax:408-493-1801 Email:[email protected]

Products of BioVision, Inc.,

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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    Brief introduction:

    IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Brief introduction:

    Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5.02 ± 0.60 nM). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC1...

  • Chemical Name: PF-04554878
    CAS No.: 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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    Brief introduction:

    PF-04554878 is potent, ATP-competitive, focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. PF-04554878 inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. A combination of PF-04554878 and paclitaxel markedly decreases proliferation and incre...

  • Chemical Name: Ozanimod
    CAS No.: 1306760-87-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RPC-1063 Quality Control & MSDS Files:
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    Brief introduction:

    Ozanimod (RPC1063) is an orally bioavailable agonist of the sphingosine-1-phosphate receptor subtypes 1 (S1P1) and 5 (S1P5). S1P receptors belong to the family of G-protein-coupled receptor which contains five subtypes, denoting S1P1-5. S1P receptors are involved in coronary artery caliber, endothelial integrity, cardiac funct...

  • Chemical Name: YH239-EE
    CAS No.: 1364488-67-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: YH 239-EE;YH 239 EE; ethyl ... Quality Control & MSDS Files:
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    Brief introduction:

    YH239-EE is potent p53-MDM2 interaction inhibitor that induces cell cycle arrest leading to potential apoptosis by p53 activation and downstream target in AML cells with p53 mutation

  • Chemical Name: Serabelisib
    CAS No.: 1268454-23-4 Purity: Appearances: White to gray Solid
    Brand: Synonyms: Serabelisib;INK1117 Quality Control & MSDS Files:
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    Serabelisib is a potent inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC₅₀ = 15 nM for PI3Kα vs. >1 µM for other isoforms, as well as for mTOR). MLN1117 inhibits AKT phosphorylation and growth in PIK3CA mutant breast cancer cells with IC₅₀ values around ...

  • Chemical Name: Fidaxomicin
    CAS No.: 873857-62-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: OPT-80;PAR-101;Dificid;Difi... Quality Control & MSDS Files:
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    Brief introduction:

    Fidaxomycin is a natural macrocyclic antibiotic and RNA polymerase inhibitor that displays selectivity for Gram-positive bacteria over Gram-negative bacteria (IC₅₀s = 0.4 and 6 μM, respectively). It shows potent antibacterial activity against most Gram-positive bacteria and effectively targets the Gram-positive C. di...

  • Chemical Name: TGR-1202
    CAS No.: 1532533-67-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: TGR 1202;TGR1202; (S)-2-(1-... Quality Control & MSDS Files:
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    Brief introduction:

    TGR-1202 (also known as RP5264), is a highly specific inhibitor of PI3Kδ, targeting the δ isoform with nanomolar potency and several-fold selectivity over the α, β, and g isoforms of PI3K.

  • Chemical Name: MIF-Antagonist, ISO-1
    CAS No.: 478336-92-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: ISO 1;ISO1;MIF Antagonist; ... Quality Control & MSDS Files:
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    Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor (TNF) release from macrophages isolated from LPS- treated wild type mice but has no effect on cytokine release from MIF deficient m...

  • Chemical Name: SIRT2 Inhibitor
    CAS No.: 420831-40-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AK 7;AK7; 3-(azepan-1-ylsul... Quality Control & MSDS Files:
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    Brief introduction:

    Brain- permeable. A potent and selective sirtuin 2 deacetylase (SIRT2) inhibitor. Reduces neuronal cholesterol by inhibiting SIRT2 activity.

  • Chemical Name: Berberine Chloride
    CAS No.: 633-65-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: BBR;Umbellatine Quality Control & MSDS Files:
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    Brief introduction:

    An isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic leukemia (ALL) cells with both MDM2 overexpression and a wild-type (wt)-p53, whereas no pro-apoptotic effect was detected in ALL...

  • Chemical Name: FR180204
    CAS No.: 865362-74-9 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: FR 180204;FR-180204; 5-(2-p... Quality Control & MSDS Files:
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    Brief introduction:

    FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively.

  • Chemical Name: Talabostat mesylate
    CAS No.: 150080-09-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: [(2R)-1-[(2S)-2-Amino-3-met... Quality Control & MSDS Files:
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    Brief introduction:

    Talabostat is a nonselective inhibitor of post-proline cleaving serine proteases. The inhibition of the highly related cytosolic serine proteases Dpp8 and Dpp9 (Dpp8/9) by Val-boroPro was recently demonstrated to trigger an immunostimulatory form of programmed cell death known as pyroptosis selectively in monocytes and ma...

  • Chemical Name: CFTR Inhibitor-172
    CAS No.: 307510-92-5 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: CFTR Inhibitor-172;CFTRinh-... Quality Control & MSDS Files:
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    Brief introduction:

    A potent, reversible, selective, CFTR chloride channel blocker. Inhibits CFTR short-circuit current in < 2 minutes in a voltage-independent manner (Ki = ~ 300 nM). At concentrations fully inhibiting CFTR, CFTR(inh)-172 does not block increase of cellular cAMP or inhibit non-CFTR Cl(-) channels, multidrug resistance protein-...

  • Chemical Name: DMH-1
    CAS No.: 1206711-16-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: DMH1;DMH 1; 4-(6-(4-isoprop... Quality Control & MSDS Files:
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    Brief introduction:

    DMH-1 is an analog of Dorsomorphin (Cat. No. 1686) that acts as a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH-1 exclusively targets the BMP but not the VEGF pathway. Blocks BMP4-induced phosphorylation of Smads 1, 5 and 8 in HEK293 cells. Promotes neurogenesis in human induced pluripotent stem cells (iPSCs...

  • Chemical Name: SKPin C1
    CAS No.: 432001-69-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: SKPin C1; (Z)-2-(4-bromo-2-... Quality Control & MSDS Files:
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    Brief introduction:

    Inhibits the cullin-RING ubiquitin E3 ligase SCF-Skp2. Selectively inhibits Skp2-mediated p27 degradation by reducing p27 binding. In cancer cells, the compound induces p27 accumulation and promotes cell type-specific blocks in G1 or G2/M phases.

  • Chemical Name: T-5224
    CAS No.: 530141-72-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: T5224;T 5224; 3-(5-(4-(cycl... Quality Control & MSDS Files:
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    Brief introduction:

    T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1 that ameliorates liver injury and improves survival through decreasing production of pro-inflammatory cytokines and chemokines in endotoxemic mice.

  • Chemical Name: CB-839
    CAS No.: 1439399-58-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-(pyridin-2-yl)-N-(5-(4-(6... Quality Control & MSDS Files:
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    Brief introduction:

    CB-839 is a potent, selective, and orally bioavailable inhibitor of both splice variants of glutaminase (KGA and GAC); inhibits recombinant GAC with an IC₅₀ of <15 nM. CB-839 displays antiproliferative activity in a triple-negative breast cancer (TNBC) cell line, HCC-1806, that is associated with a marked decrease in glutam...

  • Chemical Name: Caspase-Family Inhibitor Z-VAD-FMK
    CAS No.: 187389-52-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Z-Val-Ala-Asp(OMe)-FMK Quality Control & MSDS Files:
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    Brief introduction:

    A synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used in both in vitro and in vivo studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTI...

  • Chemical Name: JNJ-27018966
    CAS No.: 864821-90-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: JNJ 27018966;JNJ27018966;JN... Quality Control & MSDS Files:
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    Brief introduction:

    JNJ-27018966 is an orally active μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist, with powerful antidiarrheal and analgesic activity. It is believed to act locally in the enteric nervous system, and has no adverse effects in the central nervous system.