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Fleton Natural Products Co., Ltd.

21

Basic Information

Company Name:Fleton Natural Products Co., Ltd.

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Fleton Natural Products Co., Ltd.

Web: www.fleton.com TEL:+86 (28) 8440-0798 Fax:+86 (28) 8440-0789 Email:[email protected],[email protected]

Products of Fleton Natural Products Co., Ltd.

  • Chemical Name: Protopanaxatriol
    CAS No.: 1453-93-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (3S,5R,6S,8R,9R,10R,12R,13R... Quality Control & MSDS Files:
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    Brief introduction:

    Protopanaxatriol is a natural <b>PPARγ</b> antagonist with an <b>IC<sub>50</sub></b> of 11.75 μM (<b>K<sub>i</sub></b>=4.2 μM).

  • Chemical Name: Ginsenoside Rh2
    CAS No.: 78214-33-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 20(S)-Ginsenoside Rh2; (2R,... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rh2 is isolated from the root of <i>Ginseng</i>. Ginsenoside Rh2 induces the activation of <b>caspase-8</b> and <b>caspase-9</b>. Ginsenoside Rh2 induces cancer cell <b>apoptosis</b> in a multi-path manner.

  • Chemical Name: Ginsenoside Rh1
    CAS No.: 63223-86-9 Purity: Appearances:
    Brand: Synonyms: (3beta,6alpha,12beta)-3,12,... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rh1 is isolated from the root of <i>Panax Ginseng</i>. Ginsenoside Rh1 inhibits the expression of <b>PPAR-γ</b>, <b>TNF-α</b>, <b>IL-6</b>, and <b>IL-1β</b>.

  • Chemical Name: Ginsenoside Rg2
    CAS No.: 52286-74-5 Purity: Appearances:
    Brand: Synonyms: (2S,3R,4R,5R,6S)-2-(((2R,3R... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 acts as a <b>NF-κB</b> inhibitor. Ginsenoside Rg2 also reduces <b>Aβ<sub>1-42</sub></b> accumulation.

  • Chemical Name: Ginsenoside Rf
    CAS No.: 52286-58-5 Purity: Appearances:
    Brand: Synonyms: (2S,3R,4S,5S,6R)-2-(((2R,3R... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits <b>N-type Ca<sup>2+</sup> channel</b>.

  • Chemical Name: Ginsenoside F2
    CAS No.: 62025-49-4 Purity: Appearances:
    Brand: Synonyms: (2R,3R,4S,5S,6R)-2-(((3S,5R... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside F2 is found in species of Panax. It inhibits hair cell apoptosis, decreases lipid accumulation in adipocytes, and induces formation of acidic vesicles, autophagy and mitochondrial apoptosis in breast cancer stem cells.

  • Chemical Name: Ginsenoside F1
    CAS No.: 53963-43-2 Purity: Appearances:
    Brand: Synonyms: 20(S)-Ginsenoside F1; (2R,3... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of <b>CYP3A4</b> activity and weaker inhibition of CYP2D6 activity.

  • Chemical Name: Panaxatriol
    CAS No.: 32791-84-7 Purity: Appearances:
    Brand: Synonyms: (3S,5R,6R,8R,9R,10R,12R,13R... Quality Control & MSDS Files:
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    Brief introduction:

    Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities.

  • Chemical Name: Panaxadiol
    CAS No.: 19666-76-3 Purity: Appearances:
    Brand: Synonyms: (3S,5R,8R,9R,10R,12R,13R,14... Quality Control & MSDS Files:
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    Brief introduction:

    Panaxadiol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. It inhibits Ca2+ channels, decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential.

  • Chemical Name: NMDA
    CAS No.: 6384-92-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N-Methyl-D-aspartic acid; (... Quality Control & MSDS Files:
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    Brief introduction:

    NMDA(N-Methyl-D-aspartic acid) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. IC50 value: Target: NMDA receptor NMDA is a water-soluble synthetic substance that is not normally found in biological tissue.

  • Chemical Name: Ginsenoside Rg1
    CAS No.: 22427-39-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (3b,6a,12b)-3,12-Dihydroxyd... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rg1 is one of the major active components of ginseng. Ginsenoside Rg1 displays promising effects by reducing cerebral <b>Aβ</b> levels. Ginsenoside Rg1 also reduces <b>NF-κB</b> nuclear translocation.

  • Chemical Name: Ginsenoside Re
    CAS No.: 52286-59-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Panaxoside Re, Sanchinoside... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Re is a major ginsenoside in ginseng and belongs to 20(S)-protopanaxatriol group. It has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions.

  • Chemical Name: Ginsenoside Rd
    CAS No.: 52705-93-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-O-beta-D-Glucopyranosyl-(... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rd, a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity.

  • Chemical Name: Ginsenoside Rc
    CAS No.: 11021-14-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 20-[(6-O-alpha-L-Arabinofur... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rc, one of major Ginsenosides from <i>Panax ginseng</i>, enhances GABA receptor<sub>A</sub> (<b>GABA<sub>A</sub></b>)-mediated ion channel currents (I<sub>GABA</sub>). Ginsenoside Rc inhibits the expression of <b>TNF-α</b> and <b>IL-1β</b>.

  • Chemical Name: Ginsenoside Rb3
    CAS No.: 68406-26-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Dammarane,β-D-glucopyranosi... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rb3 is found in species of Panax. It inhibits contractions in aortic rings, decreases blood glucose levels, and improves oral glucose tolerance, improves immobility time in the forced swim tail suspension, and learned helplessness tests, and inhibits oxidative damage.

  • Chemical Name: Ginsenoside Rb2
    CAS No.: 11021-13-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 20-((6-O-alpha-L-Arabinopyr... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rb2 is one of the main bioactive components of ginseng extracts. Rb2 can upregulate <b>GPR120</b> gene expression.

  • Chemical Name: Ginsenoside Rb1
    CAS No.: 41753-43-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (3beta,12beta)-20-[(6-O-bet... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits <b>Na<sup>+</sup>, K<sup>+</sup>-ATPase</b> activity with an <b>IC<sub>50</sub></b> of 6.3±1.0 μM. Ginsenoside also inhibits <b>IRAK-1</b> activation and phosphorylation of <b>NF-κB p65</b> .

  • Chemical Name: Protopanaxadiol
    CAS No.: 7755-01-3 Purity: Appearances:
    Brand: Synonyms: (3S,5R,8R,9R,10R,12R,13R,14... Quality Control & MSDS Files:
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    Brief introduction:

  • Chemical Name: Ginsenoside Rg3
    CAS No.: 38243-03-7 Purity: Appearances:
    Brand: Synonyms: beta-D-Glucopyranoside,(3be... Quality Control & MSDS Files:
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    Brief introduction:

    R-Ginsenodie Rg3 γ2 GABA-A receptor agonist, 7.1 K+ channel activator, α10 nAChR antagonist found in Panax. It exhibits a wide variety of biological activities, including decreasing expression of pro-inflammatory cytokines, reducing oxidative stress, and inhibiting tubular formation and migration of endothelial progenitor cells.

  • Chemical Name: Ginsenoside C-K
    CAS No.: 39262-14-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Ginsenoside K;Ginsenoside c... Quality Control & MSDS Files:
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    Brief introduction:

    Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing <b>iNOS</b> and <b>COX-2</b>. Ginsenoside C-K exhibits an inhibition against the activity of <b>CYP2C9</b> and <b>CYP2A6</b> in human liver microsomes with <b>IC<sub>50</sub></b>s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.

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