Discovery Fine Chemicals Ltd.

Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.

Dactinomycin D(Actinomycin D; Oncostatin K) is the most significant member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces. IC50 value: Target: RNA polymerase; DNA/RNA synthesis Actinomycin D was the first antibiotic shown to have anti-cancer activity.

Homatropine Bromide is muscarinic AChR antagonist that is an anticholinergic medication. Target: mAChR Homatropine is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system.

Ampicillin Sodium is an orally active broad-spectrum antibiotic. Target: Antibacterial Ampicillin is an antibiotic useful for the treatment of a number of bacterial infections.

NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Target: Others NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. Target: Estrogen Receptor/ERR A recent study shows that estrogen (estrone, estradiol, and estriol) inhibits Alzheimer's disease-associated low-order Aβ oligomer formation, and among them, estriol shows the strongest ...

Isoniazid is an antibacterial agent used primarily as a tuberculostatic. Target: Antibacterial Isoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M.

Endogenous neurotransmitter. Acts at nicotinic and muscarinic acetylcholine receptors.

Hydrochlorothiazide is a diuretic drug of the thiazide class.

Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. Target: Nucleoside antimetabolite/analog Adenosine plays an important role in biochemical processes, such as energy transfer — as adenosine triphosphate (ATP) and adenosine diphosphate (ADP...

Odorless orange-yellow needles or platelets. Darkens and chars from approximately 482°F.

Guanidine HCl, the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant. Target: Others Guanidine HCl is the most popular protein denaturant.

Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.

Estradiol (E2) is a potent mammalian estrogenic hormone that is produced in the ovaries (by the granulosa cells), placenta, testis and possibly the adrenal cortex. Target: Estrogen Receptors Estradiol (E2 or 17β-estradiol, also oestradiol) is a sex hormone.

Furosemide (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema. Target: NKCC Furosemide (INN/BAN) or frusemide is a loop diuretic used in the treatment of congestive heart failure and edema.

Hydrocortisone is a main glucocorticoid secreted by the adrenal cortex. Target: Glucocorticoid Receptor Hydrocortisone as an anti-inflammatory and immuno-suppressant agent has multiple mechanisms of action.

Alizarin strongly inhibits P450 isoform CYP1A1, CYP1A2 and <b>CYP1B1</b> with <b>IC50</b> of 6.2 μM, 10.0 μM and 2.7 μM, respectively; weakly inhibits CYP2A6 and CYP2E1, and does not inhibit CYP2C19, CYP3A4 and CYP3A5.

A white crystalline solid. Slightly soluble in water. The primary hazard is the potential for environmental damage if released. Immediate steps should be taken to limit spread to the environment. Used to make other chemicals, as a food preservative, and for other uses.

Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring via a β-N9-glycosidic bond.