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Clearsynth Labs Limited

367

Basic Information

Company Name:Clearsynth Labs Limited

Business Type:Chemical manufacturer

Total NO.Employees:200

Country/Region:India

Certificates: ISO 9001-2008;ISO 14001-2004;OHSAS 18001-2007

Year Established:

Introduction of Clearsynth Labs Limited

Clearsynth is a technology based, research driven enterprise with the World's Largest Inventory of Reference Standards & Research Chemicals. We aim to enable the research community in accelerated discovery via synthesis of complex and difficult to make compounds.

Web: www.clearsynth.com TEL:Worldwide Helpline No. +1-415-685-4395; US & Canada (Toll-free) : +1-800-650-8239; Europe : +44-20-3286-0885; India : +91-22-26355700 Fax: Email:[email protected]

Products of Clearsynth Labs Limited

  • Chemical Name: Fidaxomicin
    CAS No.: 873857-62-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: OPT-80;PAR-101;Dificid;Difi... Quality Control & MSDS Files:
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    Brief introduction:

    Fidaxomicin(OPT-80; PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug; selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.

  • Chemical Name: Pneumocandin B0
    CAS No.: 135575-42-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N-((2R,6S,9S,11R,12R,14aS,1... Quality Control & MSDS Files:
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    Brief introduction:

    Pneumocandin B0(L-688786), a key intermediate in the synthesis of the antifungal agent, Cancidas, has led to the identification of several materials with potential for improved performance.

  • Chemical Name: SN 2
    CAS No.: 823218-99-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: SN2;SN-2; 3-mesityl-3a,4,5,... Quality Control & MSDS Files:
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    Brief introduction:

    SN 2 is a novel and potent small molecule activator of TRPML3 with EC50 of 1.13 uM. IC50 value: 1.13 uM (EC50) Target: TRPML3 activator Compounds SF21, SF-41, and SN-2 elicited a much more rapid increase than the other compounds, with SF-33 and SF 51 displaying the slowest kinetics.

  • Chemical Name: BTS
    CAS No.: 1576-37-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N-Benzyl-p-toluenesulfonami... Quality Control & MSDS Files:
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    Brief introduction:

    BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility.

  • Chemical Name: Helioxanthin derivative 5-4-2
    CAS No.: 203935-39-1 Purity: Appearances:
    Brand: Synonyms: Helioxanthin 5-4-2; 10-(ben... Quality Control & MSDS Files:
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    Brief introduction:

    Helioxanthin derivative 5-4-2 is an analogue of helioxanthin, exhibites significant in vitro anti-HBV activity with EC50 of 0.08 uM in HepG2.2.15 cells. IC50 value: 0.08 uM (EC50) [1][2] Target: Anti-HBV Helioxanthin derivative 5-4-2 had potent anti-HBV activities in HepG2.2.15 cells, with the EC50s of 1 and 0.08 microM, respectively.

  • Chemical Name: Helioxanthin
    CAS No.: 18920-47-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: ACH-126447;ACH 126447;ACH12... Quality Control & MSDS Files:
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    Brief introduction:

    Helioxanthin(ACH126447) and its analogues exhibit significant in vitro antiviral activity against hepatitis B virus (HBV, EC50=1 uM) and flavivirus. IC50 value: 1/3/2 uM (EC50, HBV/HCV/HSV-1) [1] Target: Anti-HBV;Anti flavivirus in vitro: Helioxanthin and its analogues decreased cellular RNA levels of HBV and antigen expression as w...

  • Chemical Name: 7-Epi-docetaxel
    CAS No.: 153381-68-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (2aR,4R,4aS,6R,9R,11S,12R,1... Quality Control & MSDS Files:
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    Brief introduction:

    7-Epi-10-oxo-docetaxel (Docetaxel Impurity C; 7-Epitaxotere) is a impurity of docetaxel.

  • Chemical Name: 10-Oxo Docetaxel
    CAS No.: 167074-97-7 Purity: Appearances:
    Brand: Synonyms: (2aR,4S,4aS,9R,11S,12R,12aR... Quality Control & MSDS Files:
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    Brief introduction:

    10-Oxo Docetaxel(Docetaxel Impurity) is a novel taxoid having remarkable anti-tumor properties and a Docetaxel intermediate.

  • Chemical Name: AVX 13616
    CAS No.: 900814-48-4 Purity: Appearances:
    Brand: Synonyms: AVX13616;AVX-13616; isopent... Quality Control & MSDS Files:
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    AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens. IC50 value: 2-4 ug/ml (MICs) Target: antibacterial agent AVX13616 was as active as mupirocin in a nasal decolonization model but required only a single application.

  • Chemical Name: Sevelamer (hydrochloride)
    CAS No.: 152751-57-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 2-Propen-1-amine polymer wi... Quality Control & MSDS Files:
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    Brief introduction:

    Sevelamer Hcl is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.

  • Chemical Name: Satraplatin
    CAS No.: 129580-63-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Bis(acetato-O)amminedichlor... Quality Control & MSDS Files:
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    Brief introduction:

    Satraplatin(BMS182751; BMY45594; JM216) is a platinum-based antineoplastic agent that is under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. IC50 value: Target: DNA alkylator/crosslinker Satraplatin is the first orally active platinum-based chemotherapeutic drug.

  • Chemical Name: GBR 12935
    CAS No.: 76778-22-8 Purity: Appearances:
    Brand: Synonyms: GBR12935;GBR-12935; 1-(2-(b... Quality Control & MSDS Files:
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    Brief introduction:

    GBR 12935 is a potent, and selective dopamine reuptake inhibitor. IC50 value: Target: dopamine reuptake inhibitor in vitro: The calculated Kd of [3H]GBR-12935 binding to CYP2D6 was 42.2 nM, indicating that GBR-12935 has a high affinity for CYP2D6.

  • Chemical Name: GBR 12935 (dihydrochloride)
    CAS No.: 67469-81-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: GBR12935 dihydrochloride;GB... Quality Control & MSDS Files:
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    GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor. IC50 value: Target: dopamine reuptake inhibitor in vitro: The calculated Kd of [3H]GBR-12935 binding to CYP2D6 was 42.2 nM, indicating that GBR-12935 has a high affinity for CYP2D6.

  • Chemical Name: RTA-408
    CAS No.: 1474034-05-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Omaveloxolone Quality Control & MSDS Files:
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    Brief introduction:

    RTA-408 is an antioxidant inflammation modulator (AIM), which activates <b>Nrf2</b> and suppresses nitric oxide (NO).

  • Chemical Name: DAB
    CAS No.: 7411-49-6 Purity: Appearances: light grey Solid
    Brand: Synonyms: 3,3'-Diaminobenzidine tetra... Quality Control & MSDS Files:
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    Brief introduction:

    3,3'-Diaminobenzidine(DAB) is an organic compound that is both chemically and thermodynamically stable; DAB has been used in immunohistochemical staining of nucleic acids and proteins.

  • Chemical Name: Difluprednate
    CAS No.: 23674-86-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Durezol; (6S,8S,9R,10S,11S,... Quality Control & MSDS Files:
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    Brief introduction:

    Difluprednate(Durezol) is a corticosteroid, approved difluprednate for the treatment of post-operative ocular inflammation and pain. IC50 value: Target: Difluprednate ophthalmic emulsion 0.05% is also being studied in other ocular inflammatory diseases, including a U.S.

  • Chemical Name: Savolitinib
    CAS No.: 1313725-88-0 Purity: Appearances: light yellow to khaki Solid
    Brand: Synonyms: Volitinib;HMPL-504;AZD-6094 Quality Control & MSDS Files:
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    Brief introduction:

    Savolitinib (volitinib, AZD6094, HMPL-504) is a novel, potent, and selective <b>MET</b> inhibitor currently in clinical development in various indications, including PRCC. The <b>IC50</b> values of this compound for c-Met and p-Met are 5 nM and 3 nM, respectively. It shows exquisite selectivity for c-Met over 274 kinase.

  • Chemical Name: Amlodipine (maleate)
    CAS No.: 88150-47-4 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Quality Control & MSDS Files:
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  • Chemical Name: Heparin
    CAS No.: 9005-49-6 Purity: Appearances: white
    Brand: Synonyms: 6-((5-acetamido-4,6-dihydro... Quality Control & MSDS Files:
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    Brief introduction:

    Heparin, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.