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Chemical Name:
Ropinirole (hydrochloride)
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CAS No.:
91374-20-8
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Appearances: Light yellow to yellow Solid |
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Synonyms: SKF101468 hydrochloride;SKF... |
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Brief introduction:
Ropinirole hydrochloride(SKF101468 hydrochloride) a selective dopamine D2 receptor inhibitor with IC50 of 29 nM.
Target: Dopamine D2 Receptor
Ropinirole (50 mg/kg, i.p.) causes biphasic spontaneous locomotor activity in mice.
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Chemical Name:
Desonide
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CAS No.:
638-94-8
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: (11b,16a)-11,21-Dihydroxy-1... |
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Brief introduction:
Desonide is a nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Target: Glucocorticoid Receptor
Desonide is a low-potency topical corticosteroid that has been used for decades in the treatment of steroid-responsive dermatoses [1].
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Chemical Name:
Bendamustine (hydrochloride)
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CAS No.:
3543-75-7
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: 1-Methyl-5-bis(2-chloroethy... |
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Brief introduction:
Bendamustine Hcl(SDX105; EP-3101) is a DNA-damaging agent with IC50 of 50 μM.
Target: Others
Approved: March 2008
Treatment with Bendamustine results in a 60% to 80% down-regulation of the mRNA expression of all three of these genes [polo-like kinase 1 (PLK-1), Aurora Kinase A, and cyclin B1] in SU-DHL-9 cells.
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Chemical Name:
2,4-Thiazolidinedione
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CAS No.:
2295-31-0
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Synonyms: Thiazolidine-2,4-dione; thi... |
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Chemical Name:
Budesonide
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CAS No.:
51333-22-3
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: 16,17-Butylidenebis(oxy)-11... |
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Brief introduction:
Budesonide is a glucocorticoid used in the management of asthma.
Target: Glucocorticoid Receptor
Budesonide is a glucocorticoid used in the management of asthma, the treatment of various skin disorders, and allergic rhinitis.
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Chemical Name:
Milrinone
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CAS No.:
78415-72-2
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: Corotrope;Primacor IV;Win 4... |
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Brief introduction:
Milrinone(Win 47203) is a PDE3 inhibitor that increases intracellular cyclic adenosine monophosphate resulting in improved ventricular function and vasodilation.
IC50 Value: 2 mM( inhibiting human platelet aggregation) [3]
Target: PDE3
in vitro: Milrinone inhibited PDE4 in addition to PDE3 activity.
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Chemical Name:
Sarpogrelate (hydrochloride)
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CAS No.:
135159-51-2
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Purity: |
Appearances: White to off-white Solid |
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Synonyms: (+/-)-2-(Dimethylamino)-1-{... |
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Brief introduction:
Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.
Target: 5-HT2 Recepter
Sarpogrelate is a drug which acts as an antagonist at the 5HT2A and 5-HT2B receptors.
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Chemical Name:
Palonosetron (Hydrochloride)
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CAS No.:
135729-62-3
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Purity: |
Appearances: White to off-white solid |
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Synonyms: (3aS)-2-(3S)-1-Azabicyclo[2... |
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Brief introduction:
Palonosetron Hcl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
IC50 Value:
Target: 5-HT Receptor
Palonosetron is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course ...
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Chemical Name:
4,4'-Dimethyl-2,2'-bipyridine
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CAS No.:
1134-35-6
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Synonyms: 2,2'-Bi(γ-picoline); 4,4'-D... |
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Chemical Name:
4,4'-Dichloro-2,2'-bipyridine
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CAS No.:
1762-41-0
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Synonyms: 4,4'-dichloro-2,2'-bipyridine |
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